Matches in SemOpenAlex for { <https://semopenalex.org/work/W4214713042> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W4214713042 endingPage "26" @default.
- W4214713042 startingPage "19" @default.
- W4214713042 abstract "Objective: To determine the efficacy of letrozole in suppressing estradiol levels during ovarian stimulation in cancer patients. Methods: A retrospective chart review of cancer patients undergoing ovarian stimulation for fertility preservation between 2014-2019 at a private university-affiliated fertility clinic in Canada was conducted. Ovarian stimulation was completed with no letrozole (Group A, n = 10), and adjuvant daily letrozole use at 5.0 (Group B, n = 34) or 7.5 mg (Group C, n = 61). The primary outcomes were peak estradiol levels and oocyte yield. ANOVA with a post hoc two-tailed t-test assuming equal variance was utilized as a statistical method. Result(s): Patient age and AFC count were not different between groups. The yield of mature eggs was not different at each letrozole dose; 9.2 ± 6.0, 13.9 ± 6.5 and 12.7 ± 7.2 for Groups A to C respectively (p = 0.18). Mean estradiol levels(pmol/L) were reduced in a dose-dependent manner; 7432 ± 4553 for Group A, 2072 ± 1656 for Group B, and 1445 ±1238 for Group C (A vs. C, p vs. C, p Conclusion(s): The use of letrozole during ovarian stimulation for oocyte and embryo cryopreservation in cancer patients can maintain physiologic estradiol levels, while ensuring satisfactory oocyte and embryo yield. Letrozole can, therefore, minimize the theoretical risk of stimulating residual and metastatic diseases, while still optimizing future fertility outcomes." @default.
- W4214713042 created "2022-03-02" @default.
- W4214713042 creator A5045923579 @default.
- W4214713042 creator A5055361525 @default.
- W4214713042 date "2022-01-01" @default.
- W4214713042 modified "2023-10-18" @default.
- W4214713042 title "A Retrospective Study on the Use of High-Dose Letrozole while Undergoing Ovarian Stimulation for Oocyte and Embryo Cryopreservation in Cancer Patients" @default.
- W4214713042 cites W1271389891 @default.
- W4214713042 cites W1928619520 @default.
- W4214713042 cites W1966623655 @default.
- W4214713042 cites W1988822590 @default.
- W4214713042 cites W1994303381 @default.
- W4214713042 cites W1995249735 @default.
- W4214713042 cites W1999183598 @default.
- W4214713042 cites W2021291529 @default.
- W4214713042 cites W2047130151 @default.
- W4214713042 cites W2067248802 @default.
- W4214713042 cites W2074979671 @default.
- W4214713042 cites W2080221226 @default.
- W4214713042 cites W2100196672 @default.
- W4214713042 cites W2101881391 @default.
- W4214713042 cites W2112907191 @default.
- W4214713042 cites W2127006753 @default.
- W4214713042 cites W2132173246 @default.
- W4214713042 cites W2137136818 @default.
- W4214713042 cites W2138674040 @default.
- W4214713042 cites W2146519887 @default.
- W4214713042 cites W2161454439 @default.
- W4214713042 cites W2168363199 @default.
- W4214713042 cites W2237181971 @default.
- W4214713042 cites W2510160379 @default.
- W4214713042 cites W2906845633 @default.
- W4214713042 cites W776503986 @default.
- W4214713042 doi "https://doi.org/10.4236/arsci.2022.101003" @default.
- W4214713042 hasPublicationYear "2022" @default.
- W4214713042 type Work @default.
- W4214713042 citedByCount "0" @default.
- W4214713042 crossrefType "journal-article" @default.
- W4214713042 hasAuthorship W4214713042A5045923579 @default.
- W4214713042 hasAuthorship W4214713042A5055361525 @default.
- W4214713042 hasBestOaLocation W42147130421 @default.
- W4214713042 hasConcept C121608353 @default.
- W4214713042 hasConcept C126322002 @default.
- W4214713042 hasConcept C143998085 @default.
- W4214713042 hasConcept C16685009 @default.
- W4214713042 hasConcept C196843134 @default.
- W4214713042 hasConcept C2776690073 @default.
- W4214713042 hasConcept C2777176818 @default.
- W4214713042 hasConcept C2777904497 @default.
- W4214713042 hasConcept C2778459216 @default.
- W4214713042 hasConcept C2778812593 @default.
- W4214713042 hasConcept C2908647359 @default.
- W4214713042 hasConcept C29456083 @default.
- W4214713042 hasConcept C518429986 @default.
- W4214713042 hasConcept C530470458 @default.
- W4214713042 hasConcept C71924100 @default.
- W4214713042 hasConcept C86803240 @default.
- W4214713042 hasConcept C95444343 @default.
- W4214713042 hasConcept C99454951 @default.
- W4214713042 hasConceptScore W4214713042C121608353 @default.
- W4214713042 hasConceptScore W4214713042C126322002 @default.
- W4214713042 hasConceptScore W4214713042C143998085 @default.
- W4214713042 hasConceptScore W4214713042C16685009 @default.
- W4214713042 hasConceptScore W4214713042C196843134 @default.
- W4214713042 hasConceptScore W4214713042C2776690073 @default.
- W4214713042 hasConceptScore W4214713042C2777176818 @default.
- W4214713042 hasConceptScore W4214713042C2777904497 @default.
- W4214713042 hasConceptScore W4214713042C2778459216 @default.
- W4214713042 hasConceptScore W4214713042C2778812593 @default.
- W4214713042 hasConceptScore W4214713042C2908647359 @default.
- W4214713042 hasConceptScore W4214713042C29456083 @default.
- W4214713042 hasConceptScore W4214713042C518429986 @default.
- W4214713042 hasConceptScore W4214713042C530470458 @default.
- W4214713042 hasConceptScore W4214713042C71924100 @default.
- W4214713042 hasConceptScore W4214713042C86803240 @default.
- W4214713042 hasConceptScore W4214713042C95444343 @default.
- W4214713042 hasConceptScore W4214713042C99454951 @default.
- W4214713042 hasIssue "01" @default.
- W4214713042 hasLocation W42147130421 @default.
- W4214713042 hasOpenAccess W4214713042 @default.
- W4214713042 hasPrimaryLocation W42147130421 @default.
- W4214713042 hasRelatedWork W1968357194 @default.
- W4214713042 hasRelatedWork W1991609875 @default.
- W4214713042 hasRelatedWork W2130798788 @default.
- W4214713042 hasRelatedWork W2146511467 @default.
- W4214713042 hasRelatedWork W2168025893 @default.
- W4214713042 hasRelatedWork W2243526015 @default.
- W4214713042 hasRelatedWork W2761860113 @default.
- W4214713042 hasRelatedWork W2916345045 @default.
- W4214713042 hasRelatedWork W2924128835 @default.
- W4214713042 hasRelatedWork W3198772393 @default.
- W4214713042 hasVolume "10" @default.
- W4214713042 isParatext "false" @default.
- W4214713042 isRetracted "false" @default.
- W4214713042 workType "article" @default.