Matches in SemOpenAlex for { <https://semopenalex.org/work/W4214808224> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W4214808224 endingPage "1517" @default.
- W4214808224 startingPage "1517" @default.
- W4214808224 abstract "<ns4:p>Schistosomiasis remains one of the neglected tropical diseases (NTDs) impacting millions of people around the world. The World Health Organization (WHO) recently proposed a goal of elimination as a public health problem (EPHP) for schistosomiasis to be reached by 2030. Current WHO treatment guidelines for achieving EPHP focus on targeting school-aged children. The NTD Modelling Consortium has developed mathematical models to study schistosomiasis transmission dynamics and the impact of control measures. Our modelling insights on <ns4:italic>Schistosoma mansoni</ns4:italic> have shown that EPHP is likely to be attainable in low to moderate prevalence settings using the current guidelines. However, as prevalence rises within higher settings, EPHP is less likely to be achieved unless both school-aged children and adults are treated (with coverage levels increasing with the adult burden of infection). We highlight the challenges that are faced by treatment programmes, such as non-adherence to treatment and resurgence, which can hinder progress towards achieving and maintaining EPHP. Additionally, even though EPHP may be reached, prevalence can still be high due to persisting infections. Therefore, without elimination of transmission, treatment will likely have to continue to maintain EPHP. Further modelling work is being carried out, including extending our results to <ns4:italic>S. haematobium</ns4:italic>. By providing these modelling insights, we aim to inform discussions on the goals and treatment guidelines for schistosomiasis.</ns4:p>" @default.
- W4214808224 created "2022-03-05" @default.
- W4214808224 creator A5060628785 @default.
- W4214808224 date "2019-08-16" @default.
- W4214808224 modified "2023-10-18" @default.
- W4214808224 title "Insights from quantitative and mathematical modelling on the proposed WHO 2030 goal for schistosomiasis" @default.
- W4214808224 cites W1893264040 @default.
- W4214808224 cites W2129877365 @default.
- W4214808224 cites W2263290155 @default.
- W4214808224 cites W2497850966 @default.
- W4214808224 cites W2521509276 @default.
- W4214808224 cites W2587608881 @default.
- W4214808224 cites W2592296374 @default.
- W4214808224 cites W2594334664 @default.
- W4214808224 cites W2608735690 @default.
- W4214808224 cites W2620104537 @default.
- W4214808224 cites W2770987871 @default.
- W4214808224 cites W2773139889 @default.
- W4214808224 cites W2805165299 @default.
- W4214808224 cites W2895261683 @default.
- W4214808224 cites W2895421104 @default.
- W4214808224 cites W2902854501 @default.
- W4214808224 cites W2905431838 @default.
- W4214808224 cites W2912115762 @default.
- W4214808224 doi "https://doi.org/10.12688/gatesopenres.13052.1" @default.
- W4214808224 hasPublicationYear "2019" @default.
- W4214808224 type Work @default.
- W4214808224 citedByCount "8" @default.
- W4214808224 countsByYear W42148082242019 @default.
- W4214808224 countsByYear W42148082242020 @default.
- W4214808224 countsByYear W42148082242021 @default.
- W4214808224 countsByYear W42148082242022 @default.
- W4214808224 crossrefType "journal-article" @default.
- W4214808224 hasAuthorship W4214808224A5060628785 @default.
- W4214808224 hasBestOaLocation W42148082241 @default.
- W4214808224 hasConcept C138816342 @default.
- W4214808224 hasConcept C142724271 @default.
- W4214808224 hasConcept C165901193 @default.
- W4214808224 hasConcept C203014093 @default.
- W4214808224 hasConcept C2776225656 @default.
- W4214808224 hasConcept C2776246342 @default.
- W4214808224 hasConcept C2776863245 @default.
- W4214808224 hasConcept C2777445151 @default.
- W4214808224 hasConcept C2778491710 @default.
- W4214808224 hasConcept C41008148 @default.
- W4214808224 hasConcept C71924100 @default.
- W4214808224 hasConcept C761482 @default.
- W4214808224 hasConcept C76155785 @default.
- W4214808224 hasConcept C99454951 @default.
- W4214808224 hasConceptScore W4214808224C138816342 @default.
- W4214808224 hasConceptScore W4214808224C142724271 @default.
- W4214808224 hasConceptScore W4214808224C165901193 @default.
- W4214808224 hasConceptScore W4214808224C203014093 @default.
- W4214808224 hasConceptScore W4214808224C2776225656 @default.
- W4214808224 hasConceptScore W4214808224C2776246342 @default.
- W4214808224 hasConceptScore W4214808224C2776863245 @default.
- W4214808224 hasConceptScore W4214808224C2777445151 @default.
- W4214808224 hasConceptScore W4214808224C2778491710 @default.
- W4214808224 hasConceptScore W4214808224C41008148 @default.
- W4214808224 hasConceptScore W4214808224C71924100 @default.
- W4214808224 hasConceptScore W4214808224C761482 @default.
- W4214808224 hasConceptScore W4214808224C76155785 @default.
- W4214808224 hasConceptScore W4214808224C99454951 @default.
- W4214808224 hasFunder F4320306137 @default.
- W4214808224 hasFunder F4320319996 @default.
- W4214808224 hasFunder F4320334626 @default.
- W4214808224 hasLocation W42148082241 @default.
- W4214808224 hasLocation W42148082242 @default.
- W4214808224 hasLocation W42148082243 @default.
- W4214808224 hasLocation W42148082244 @default.
- W4214808224 hasOpenAccess W4214808224 @default.
- W4214808224 hasPrimaryLocation W42148082241 @default.
- W4214808224 hasRelatedWork W1993622747 @default.
- W4214808224 hasRelatedWork W2124827571 @default.
- W4214808224 hasRelatedWork W2247435327 @default.
- W4214808224 hasRelatedWork W2417101304 @default.
- W4214808224 hasRelatedWork W2579007295 @default.
- W4214808224 hasRelatedWork W2742977816 @default.
- W4214808224 hasRelatedWork W2888193100 @default.
- W4214808224 hasRelatedWork W3155948553 @default.
- W4214808224 hasRelatedWork W4235353599 @default.
- W4214808224 hasRelatedWork W4291674835 @default.
- W4214808224 hasVolume "3" @default.
- W4214808224 isParatext "false" @default.
- W4214808224 isRetracted "false" @default.
- W4214808224 workType "article" @default.