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- W4214832024 abstract "Abstract Specific interactions between receptors on cell surfaces are essential for living organisms to sense and adapt to their environment. For example, CD16A (Feγ receptor IIIA) signals a variety of immune functions upon binding of immunoglobulin (Ig) G. While receptor-ligand binding has been extensively studied in chemical terms, only until very recently has direct measurement of individual bond forces become possible. Evans et al. [1] pioneered the use of the micropipet technique to measure detachment forces between two red blood cells (RBC) crosslinked by antibodies. While these authors achieved the sensitivity necessary to detect individual bonds (in piconewton range), the forces they measured appeared to be those of uprooting the molecules from the cell membrane (cohesive detachment mode) instead of dissociating the antibody-antigen bonds (adhesive detachment mode)." @default.
- W4214832024 created "2022-03-05" @default.
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- W4214832024 date "1997-11-16" @default.
- W4214832024 modified "2023-09-29" @default.
- W4214832024 title "Dissociation of Individual Molecular Bonds Under Force" @default.
- W4214832024 doi "https://doi.org/10.1115/imece1997-0286" @default.
- W4214832024 hasPublicationYear "1997" @default.
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