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- W4214840285 endingPage "270" @default.
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- W4214840285 abstract "Microbial resistance to current antibiotics therapies is a major cause of implant failure and adverse clinical outcomes in orthopaedic surgery. Recent developments in advanced antimicrobial nanotechnologies provide numerous opportunities to effective remove resistant bacteria and prevent resistance from occurring through unique mechanisms. With tunable physicochemical properties, nanomaterials can be designed to be bactericidal, antifouling, immunomodulating, and capable of delivering antibacterial compounds to the infection region with spatiotemporal accuracy. Despite its substantial advancement, an important, but under-explored area, is potential microbial resistance to nanomaterials and how this can impact the clinical use of antimicrobial nanotechnologies. This review aims to provide a better understanding of nanomaterial-associated microbial resistance to accelerate bench-to-bedside translations of emerging nanotechnologies for effective control of implant associated infections." @default.
- W4214840285 created "2022-03-05" @default.
- W4214840285 creator A5002247965 @default.
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- W4214840285 creator A5037964704 @default.
- W4214840285 creator A5069261598 @default.
- W4214840285 date "2022-10-01" @default.
- W4214840285 modified "2023-09-30" @default.
- W4214840285 title "Microbial resistance to nanotechnologies: An important but understudied consideration using antimicrobial nanotechnologies in orthopaedic implants" @default.
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