FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4214866809> ?p ?o ?g. }

• W4214866809 abstract "Abstract Hippocampal-dependent memory is thought to be supported by distinct connectivity states, with strong input to the hippocampus benefitting encoding and weak input benefitting retrieval. Previous research in rodents suggests that the hippocampal theta oscillation orchestrates the transition between these states, with opposite phase angles predicting minimal versus maximal input. We investigated whether this phase dependence exists in humans using network-targeted intracranial stimulation. Intracranial local field potentials were recorded from individuals with epilepsy undergoing medically necessary stereotactic electroencephalographic recording. In each subject, biphasic bipolar direct electrical stimulation was delivered to lateral temporal sites with demonstrated connectivity to hippocampus. Lateral temporal stimulation evoked ipsilateral hippocampal potentials with distinct early and late components. Using evoked component amplitude to measure functional connectivity, we assessed whether the phase of hippocampal theta predicted relatively high versus low connectivity. We observed an increase in the continuous phase-amplitude relationship selective to the early and late components of the response evoked by lateral temporal stimulation. The maximal difference in these evoked component amplitudes occurred across 180 degrees of separation in the hippocampal theta rhythm; i.e., the greatest difference in component amplitude was observed when stimulation was delivered at theta peak versus trough. The pattern of theta phase dependence observed for hippocampus was not identified for control locations. These findings demonstrate that hippocampal receptivity to input varies with theta phase, suggesting that theta phase reflects connectivity states of human hippocampal networks. These findings confirm a putative mechanism by which neural oscillations modulate human hippocampal function." @default.
• W4214866809 created "2022-03-05" @default.
• W4214866809 creator A5012136362 @default.
• W4214866809 creator A5014242555 @default.
• W4214866809 creator A5031820536 @default.
• W4214866809 creator A5046631225 @default.
• W4214866809 date "2022-03-02" @default.
• W4214866809 modified "2023-09-26" @default.
• W4214866809 title "Human hippocampal responses to network intracranial stimulation vary with theta phase" @default.
• W4214866809 cites W1583309920 @default.
• W4214866809 cites W1653233231 @default.
• W4214866809 cites W1658884838 @default.
• W4214866809 cites W1659775087 @default.
• W4214866809 cites W1751585141 @default.
• W4214866809 cites W1969724616 @default.
• W4214866809 cites W1972095263 @default.
• W4214866809 cites W1973669054 @default.
• W4214866809 cites W1975095146 @default.
• W4214866809 cites W1977635108 @default.
• W4214866809 cites W1981411762 @default.
• W4214866809 cites W1983600855 @default.
• W4214866809 cites W1983813797 @default.
• W4214866809 cites W1985318799 @default.
• W4214866809 cites W1985960141 @default.
• W4214866809 cites W2009397486 @default.
• W4214866809 cites W2011481459 @default.
• W4214866809 cites W2015029893 @default.
• W4214866809 cites W2018964056 @default.
• W4214866809 cites W2020972983 @default.
• W4214866809 cites W2025180344 @default.
• W4214866809 cites W2029083932 @default.
• W4214866809 cites W2045498423 @default.
• W4214866809 cites W2049948139 @default.
• W4214866809 cites W2051508348 @default.
• W4214866809 cites W2062103513 @default.
• W4214866809 cites W2064409479 @default.
• W4214866809 cites W2064790617 @default.
• W4214866809 cites W2065096279 @default.
• W4214866809 cites W2071899885 @default.
• W4214866809 cites W2073461351 @default.
• W4214866809 cites W2074895886 @default.
• W4214866809 cites W2079129033 @default.
• W4214866809 cites W2085417748 @default.
• W4214866809 cites W2096316691 @default.
• W4214866809 cites W2096970998 @default.
• W4214866809 cites W2098022376 @default.
• W4214866809 cites W2104731571 @default.
• W4214866809 cites W2105496689 @default.
• W4214866809 cites W2106089606 @default.
• W4214866809 cites W2114151590 @default.
• W4214866809 cites W2123983635 @default.
• W4214866809 cites W2128595101 @default.
• W4214866809 cites W2136574536 @default.
• W4214866809 cites W2146303499 @default.
• W4214866809 cites W2150825673 @default.
• W4214866809 cites W2152372327 @default.
• W4214866809 cites W2152779992 @default.
• W4214866809 cites W2160967456 @default.
• W4214866809 cites W2161908852 @default.
• W4214866809 cites W2163909553 @default.
• W4214866809 cites W2253700311 @default.
• W4214866809 cites W2321260333 @default.
• W4214866809 cites W2344052780 @default.
• W4214866809 cites W2504912000 @default.
• W4214866809 cites W2886040293 @default.
• W4214866809 cites W2987927657 @default.
• W4214866809 cites W3013437496 @default.
• W4214866809 cites W4230920194 @default.
• W4214866809 doi "https://doi.org/10.1101/2022.02.28.482345" @default.
• W4214866809 hasPublicationYear "2022" @default.
• W4214866809 type Work @default.
• W4214866809 citedByCount "0" @default.
• W4214866809 crossrefType "posted-content" @default.
• W4214866809 hasAuthorship W4214866809A5012136362 @default.
• W4214866809 hasAuthorship W4214866809A5014242555 @default.
• W4214866809 hasAuthorship W4214866809A5031820536 @default.
• W4214866809 hasAuthorship W4214866809A5046631225 @default.
• W4214866809 hasBestOaLocation W42148668091 @default.
• W4214866809 hasConcept C117838684 @default.
• W4214866809 hasConcept C121332964 @default.
• W4214866809 hasConcept C148762608 @default.
• W4214866809 hasConcept C15744967 @default.
• W4214866809 hasConcept C169760540 @default.
• W4214866809 hasConcept C180205008 @default.
• W4214866809 hasConcept C24998067 @default.
• W4214866809 hasConcept C2781161787 @default.
• W4214866809 hasConcept C522805319 @default.
• W4214866809 hasConcept C62520636 @default.
• W4214866809 hasConcept C84644016 @default.
• W4214866809 hasConceptScore W4214866809C117838684 @default.
• W4214866809 hasConceptScore W4214866809C121332964 @default.
• W4214866809 hasConceptScore W4214866809C148762608 @default.
• W4214866809 hasConceptScore W4214866809C15744967 @default.
• W4214866809 hasConceptScore W4214866809C169760540 @default.
• W4214866809 hasConceptScore W4214866809C180205008 @default.
• W4214866809 hasConceptScore W4214866809C24998067 @default.
• W4214866809 hasConceptScore W4214866809C2781161787 @default.
• W4214866809 hasConceptScore W4214866809C522805319 @default.
• W4214866809 hasConceptScore W4214866809C62520636 @default.
• W4214866809 hasConceptScore W4214866809C84644016 @default.

• next