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- W4214877531 abstract "In this study, a nanocomposite scaffold composed of mesoporous bioactive glass/bacterial cellulose (MBG/BC) has been synthesized using an in situ membrane-liquid interface culture. In the resulting MBG/BC nanocomposites, MBG is homogeneously distributed in the three-dimensional BC matrix. In vitro mineralization experiments revealed that incorporating MBG into BC scaffolds enhanced their bioactivity. Subsequently, human bone marrow stromal cells (hMBSCs) were seeded onto MBG/BC scaffolds, and the effect of MBG on biocompatibility and bone regeneration was evaluated by analyzing the cell morphology, measuring cell viability, alkaline phosphatase (ALP) activity, and osteogenic-related gene expression. The results showed that MBG/BC nanocomposite scaffolds exhibited an increase in hMBSC proliferation, ALP activity, and osteogenic-related gene expression compared to bare BC scaffolds. We believe that the scalable and simple green method can be used in fabricating other BC-based nanocomposite scaffolds, and that the MBG/BC scaffolds are considered a promising candidate for treatment of bone defects." @default.
- W4214877531 created "2022-03-05" @default.
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- W4214877531 date "2022-06-01" @default.
- W4214877531 modified "2023-10-18" @default.
- W4214877531 title "Mesoporous bioactive glass/bacterial cellulose composite scaffolds for bone support materials" @default.
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- W4214877531 doi "https://doi.org/10.1016/j.colsurfa.2022.128693" @default.
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