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- W4214885023 abstract "Multivessel coronary artery disease, defined as significant stenosis in two or more major coronary arteries, is associated with high morbidity and mortality. The diagnosis and treatment of multivessel disease have evolved in the PCI era from solely a visual estimation of ischemic risk to a functional evaluation during angiography. This review summarizes the evidence and discusses the commonly used methods of multivessel coronary artery stenosis physiologic assessment.While FFR remains the gold standard in coronary physiologic assessment, several pressure-wire-based non-hyperemic indices of functional stenosis have been developed and validated as well as wire-free angiographically derived quantitative flow ratio. Identifying and treating functionally significant coronary atherosclerotic lesions reduce symptoms and major adverse cardiovascular events. Coronary physiologic assessment in multivessel disease minimizes the observer bias in visual estimates of stenosis, changes clinical management, and improves patient outcomes." @default.
- W4214885023 created "2022-03-05" @default.
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- W4214885023 date "2022-03-02" @default.
- W4214885023 modified "2023-10-05" @default.
- W4214885023 title "Physiologic Lesion Assessment to Optimize Multivessel Disease" @default.
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- W4214885023 doi "https://doi.org/10.1007/s11886-022-01675-8" @default.
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