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• W4214892203 abstract "SignificanceThe dynamics of deleterious variation under contrasting demographic scenarios remain poorly understood in spite of their relevance in evolutionary and conservation terms. Here we apply a genomic approach to study differences in the burden of deleterious alleles between the endangered Iberian lynx (Lynx pardinus) and the widespread Eurasian lynx (Lynx lynx). Our analysis unveils a significantly lower deleterious burden in the former species that should be ascribed to genetic purging, that is, to the increased opportunities of selection against recessive homozygotes due to the inbreeding caused by its smaller population size, as illustrated by our analytical predictions. This research provides theoretical and empirical evidence on the evolutionary relevance of genetic purging under certain demographic conditions." @default.
• W4214892203 created "2022-03-05" @default.
• W4214892203 creator A5001851127 @default.
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• W4214892203 creator A5086220297 @default.
• W4214892203 date "2022-03-01" @default.
• W4214892203 modified "2023-10-09" @default.
• W4214892203 title "Purging of deleterious burden in the endangered Iberian lynx" @default.
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