FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4214899593> ?p ?o ?g. }

• W4214899593 endingPage "53" @default.
• W4214899593 startingPage "46" @default.
• W4214899593 abstract "This synthesis of the literature on radiotherapy for lung cancer is based on 80 scientific articles, including 2 meta-analyses, 29 randomized studies, 19 prospective studies, and 21 retrospective studies. These studies involve 28172 patients. Basic treatment for limited-stage small cell lung cancer (SCLC), is chemotherapy. Addition of radiotherapy to the primary tumor and mediastinum reduces local recurrence, prolongs long-term survival, and is often indicated. Current, and future, studies can be expected to show successive improvements in results for SCLC by optimizing the combination of radiotherapy and chemotherapy. Should these treatments be given simultaneously or sequentially, and in which order? Which fractionation is best? Probably, no change in resource requirements for radiotherapy will be necessary, with the possible exception of changes in fractionation. Surgery constitutes primary treatment for nonsmall cell lung cancer (NSCLC) stages I and II. Radiotherapy may provide an alternative for patients who are inoperable for medical reasons. The value of radiotherapy following radical surgery for NSCLC remains to be shown. It is not indicated based on current knowledge. For NSCLC stage III, radiotherapy shrinks tumors and prolongs survival at 2 and 3 years. Whether it influences long-term survival after 5 years has not been shown. Considering the side effects of treatment, one must question whether limited improvements in survival motivate routine radiotherapy in these patients. Earlier attempts to add chemotherapy to radiotherapy to improve treatment results of NSCLC have not yielded convincing results. Several studies are currently on-going. Prophylactic cranial irradiation (PCI) greatly reduces the risk for brain metastases from SCLC. However, it has little influence on survival. Many treatment centers give PCI to SCLC patients who have achieved complete remission. This practice may be questioned since PCI is associated with serious complications. PCI is not indicated in patients with NSCLC. In SCLC, where the disease is extensive, only palliative radiotherapy is appropriate. Radiotherapy is an important treatment alternative in special palliative situations involving severe cough, severe bleeding, pain, pulmonary obstructions, and vena cava superior syndrome. In these situations, good results may be achieved with few fractions." @default.
• W4214899593 created "2022-03-05" @default.
• W4214899593 creator A5010199908 @default.
• W4214899593 date "1996-01-01" @default.
• W4214899593 modified "2023-09-25" @default.
• W4214899593 title "Lung Cancer" @default.
• W4214899593 cites W1605816160 @default.
• W4214899593 cites W1780841930 @default.
• W4214899593 cites W1835668326 @default.
• W4214899593 cites W1885320430 @default.
• W4214899593 cites W1905406155 @default.
• W4214899593 cites W1923792259 @default.
• W4214899593 cites W1935482218 @default.
• W4214899593 cites W1964402113 @default.
• W4214899593 cites W1966715368 @default.
• W4214899593 cites W1967655634 @default.
• W4214899593 cites W1969375032 @default.
• W4214899593 cites W1971476246 @default.
• W4214899593 cites W1981900821 @default.
• W4214899593 cites W1982203825 @default.
• W4214899593 cites W1984809018 @default.
• W4214899593 cites W1987028470 @default.
• W4214899593 cites W1988114301 @default.
• W4214899593 cites W1989210471 @default.
• W4214899593 cites W1989315499 @default.
• W4214899593 cites W1995606594 @default.
• W4214899593 cites W1995713828 @default.
• W4214899593 cites W1996105760 @default.
• W4214899593 cites W1996771444 @default.
• W4214899593 cites W2002089674 @default.
• W4214899593 cites W2006079563 @default.
• W4214899593 cites W2009755026 @default.
• W4214899593 cites W2010947937 @default.
• W4214899593 cites W2013808387 @default.
• W4214899593 cites W2017042556 @default.
• W4214899593 cites W2023192467 @default.
• W4214899593 cites W2023639623 @default.
• W4214899593 cites W2026019445 @default.
• W4214899593 cites W2027673513 @default.
• W4214899593 cites W2027744582 @default.
• W4214899593 cites W2031555443 @default.
• W4214899593 cites W2034440694 @default.
• W4214899593 cites W2042642004 @default.
• W4214899593 cites W2047895797 @default.
• W4214899593 cites W2050333974 @default.
• W4214899593 cites W2051767374 @default.
• W4214899593 cites W2056012403 @default.
• W4214899593 cites W2056049978 @default.
• W4214899593 cites W2060079855 @default.
• W4214899593 cites W2060711937 @default.
• W4214899593 cites W2062248834 @default.
• W4214899593 cites W2062257550 @default.
• W4214899593 cites W2064680538 @default.
• W4214899593 cites W2070000342 @default.
• W4214899593 cites W2070571726 @default.
• W4214899593 cites W2074212676 @default.
• W4214899593 cites W2077210792 @default.
• W4214899593 cites W2078916780 @default.
• W4214899593 cites W2085055339 @default.
• W4214899593 cites W2091693402 @default.
• W4214899593 cites W2092769396 @default.
• W4214899593 cites W2102062651 @default.
• W4214899593 cites W2103926757 @default.
• W4214899593 cites W2109855318 @default.
• W4214899593 cites W2115768999 @default.
• W4214899593 cites W2121624379 @default.
• W4214899593 cites W2133956068 @default.
• W4214899593 cites W2136964691 @default.
• W4214899593 cites W2142764975 @default.
• W4214899593 cites W2149195901 @default.
• W4214899593 cites W2155709777 @default.
• W4214899593 cites W2256738179 @default.
• W4214899593 cites W2258518953 @default.
• W4214899593 cites W2289340589 @default.
• W4214899593 cites W2317448174 @default.
• W4214899593 cites W2337907029 @default.
• W4214899593 cites W2341745217 @default.
• W4214899593 cites W2345887986 @default.
• W4214899593 cites W2413920060 @default.
• W4214899593 cites W4235606409 @default.
• W4214899593 cites W4244503053 @default.
• W4214899593 doi "https://doi.org/10.3109/02841869609101662" @default.
• W4214899593 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9154094" @default.
• W4214899593 hasPublicationYear "1996" @default.
• W4214899593 type Work @default.
• W4214899593 citedByCount "1" @default.
• W4214899593 crossrefType "journal-article" @default.
• W4214899593 hasAuthorship W4214899593A5010199908 @default.
• W4214899593 hasBestOaLocation W42148995931 @default.
• W4214899593 hasConcept C121608353 @default.
• W4214899593 hasConcept C126322002 @default.
• W4214899593 hasConcept C141071460 @default.
• W4214899593 hasConcept C143998085 @default.
• W4214899593 hasConcept C146357865 @default.
• W4214899593 hasConcept C151730666 @default.
• W4214899593 hasConcept C2776256026 @default.
• W4214899593 hasConcept C2776694085 @default.
• W4214899593 hasConcept C2779126056 @default.

• next