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- W4214923111 abstract "Introduction: Inverted papillomas (IPs) are rare, benign, sinonasal tumors with the ability to undergo malignant transformation. While rare, they are the most common type of papilloma within the sinonasal cavity and represent up to 5% of primary nasal cavity tumors. There have been many studies attempting to define a causal link between HPV and malignant transformation of IPs with mixed results. Additionally, these tumors have a high recurrence rate, and their malignant transformation potential has spurred significant investigation into their etiology, disease course, and treatment. Prior meta-analyses of HPV-mediated transformation of IPs have suggested a nearly 50% prevalence of HPV in IPSCC and strong bias toward the high-risk virus types, HPV16 and HPV18, in IP malignant transformation. In this study, we have identified a large, retrospective cohort of benign IPs, IP-SCC, and control sinonasal polyp tissues that have been tested for high-risk HPV types to determine the prevalence in both benign and malignant IPs." @default.
- W4214923111 created "2022-03-05" @default.
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- W4214923111 date "2022-02-01" @default.
- W4214923111 modified "2023-09-30" @default.
- W4214923111 title "The Role of Integration and HPV Status in Malignant Transformation of Inverted Papillomas" @default.
- W4214923111 doi "https://doi.org/10.1055/s-0042-1743610" @default.
- W4214923111 hasPublicationYear "2022" @default.
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