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• W4214945622 abstract "This chapter is part 1 of a two-part text. It focuses on the measurement of autonomic neuropathy, specifically Diabetic Autonomic Neuropathy. Presented in this chapter is a brief history of autonomic neuropathy and its measurements, some definitions, and a description of Parasympathetic and Sympathetic (P&S) testing. It ends with a discussion and clinical data demonstrating the progression, or natural history, of P&S dysfunction to help understand the need for P&S measurement, monitoring, and therapy even earlier than currently accepted. In part 2, the vicious cycle of cause and effect of oxidative stress and Diabetes is explored to understand therapy, including supplemental and lifestyle modifications, in addition to pharmaceuticals. Throughout the part, the morbidity and mortality risks of Diabetes and associated oxidative stress are highlighted with therapy recommended to balance the P&S and antioxidant–oxidant relationships. In conclusion, balance, as measured for the individual patient at that time in their life, is a key: antioxidant–oxidant (including sugar and insulin) at the cellular level, P&S at the system level, and psychosocial and physiological stresses and therapy at the whole-body level. Proper balance leads to an improved Quality of Life." @default.
• W4214945622 created "2022-03-05" @default.
• W4214945622 creator A5044289661 @default.
• W4214945622 date "2022-01-01" @default.
• W4214945622 modified "2023-09-25" @default.
• W4214945622 title "Diabetic autonomic neuropathy, measurement and management; part 1: measurement" @default.
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• W4214945622 doi "https://doi.org/10.1016/b978-0-12-820669-0.00007-4" @default.
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