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- W4214953646 abstract "Brain edema - a frequently fatal pathological state in which brain volume increases resulting in intracranial pressure elevation - can result from almost any insult to the brain, including traumatic brain injury. For many years, the objective of experimental studies was to find a method to prevent the development of brain edema at the onset. From this perspective, the use of methylprednisolone (MP) appears promising. High molecular MP (MW>50 kDa) can be incorporated into the brain - in the conditions of the experimental model - either by osmotic blood-brain barrier disruption (BBBd) or during the induction of cellular edema by water intoxication (WI) - a condition that increases the BBB permeability. The time window for administration of the MP should be at the earliest stages of edema. The neuroprotective effect of MP on the permeability of cytoplasmatic membranes of neuronal populations was proved. MP was administrated in three alternative ways: intraperitoneally during the induction of cytotoxic edema or immediately after finishing cytotoxic edema induction in a dose of 100 mg/kg b.w.; into the internal carotid artery within 2 h after finishing cytotoxic edema induction in a dose of 50 mg/kg b.w.; into internal carotid artery 10 min after edema induction by BBBd in a dose of 50 mg/kg b.w." @default.
- W4214953646 created "2022-03-05" @default.
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- W4214953646 date "2021-12-31" @default.
- W4214953646 modified "2023-10-03" @default.
- W4214953646 title "Effect of Methylprednisolone on Experimental Brain Edema in Rats – Own Experience Reviewed" @default.
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- W4214953646 cites W1813630596 @default.
- W4214953646 cites W1852301381 @default.
- W4214953646 cites W193249883 @default.
- W4214953646 cites W195792463 @default.
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- W4214953646 cites W1984158584 @default.
- W4214953646 cites W1989348564 @default.
- W4214953646 cites W1996449070 @default.
- W4214953646 cites W1998620774 @default.
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- W4214953646 cites W2021789707 @default.
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- W4214953646 cites W2339287211 @default.
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- W4214953646 cites W2797732082 @default.
- W4214953646 cites W2886166995 @default.
- W4214953646 cites W2970455534 @default.
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- W4214953646 doi "https://doi.org/10.33549/physiolres.934818" @default.
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