Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220657582> ?p ?o ?g. }
- W4220657582 endingPage "55" @default.
- W4220657582 startingPage "46" @default.
- W4220657582 abstract "Viral vectors are of great clinical interest due to their high efficiency, which allows them to find practical applications in gene therapy. The review presents current research data on various fish species as potential models for the use of viral vectors. During the study of high-performance adenoviral vectors data on the stable expression of transgenes in the body of Danio rerio and other fish species was obtained. The features of the use of adeno-associated vectors in the study of transneuronal transfer of the glucuronidase protein in the projection neurons of the ventral tegmental area and striatum to treat metabolic insufficiency in case of mucopolysaccharidosis VII are considered. Taking into consideration the wide set of genetically modified Danio rerio strains, ethical aspects, and the acceptability of applying this model in neurogenic studies, it is clear that Danio rerio, as well as other fish species, can be used as an alternative for early preclinical evaluation of the efficiency of viral vectors." @default.
- W4220657582 created "2022-04-03" @default.
- W4220657582 creator A5022548458 @default.
- W4220657582 creator A5027651568 @default.
- W4220657582 creator A5051710909 @default.
- W4220657582 date "2022-03-26" @default.
- W4220657582 modified "2023-10-18" @default.
- W4220657582 title "Viral Vectors in Transgenic Research: Prospects for the Treatment of CNS Diseases and Gene Therapy" @default.
- W4220657582 cites W1185489258 @default.
- W4220657582 cites W1487003008 @default.
- W4220657582 cites W1601499949 @default.
- W4220657582 cites W1964861983 @default.
- W4220657582 cites W1969869269 @default.
- W4220657582 cites W1970285081 @default.
- W4220657582 cites W1971093507 @default.
- W4220657582 cites W1972789608 @default.
- W4220657582 cites W1980911233 @default.
- W4220657582 cites W1981239255 @default.
- W4220657582 cites W1983272530 @default.
- W4220657582 cites W1983285107 @default.
- W4220657582 cites W1984686388 @default.
- W4220657582 cites W1992972394 @default.
- W4220657582 cites W1996706043 @default.
- W4220657582 cites W1999982139 @default.
- W4220657582 cites W2003456064 @default.
- W4220657582 cites W2007821283 @default.
- W4220657582 cites W2009243115 @default.
- W4220657582 cites W2010506122 @default.
- W4220657582 cites W2015527284 @default.
- W4220657582 cites W2028068426 @default.
- W4220657582 cites W2028266585 @default.
- W4220657582 cites W2028571259 @default.
- W4220657582 cites W2035509972 @default.
- W4220657582 cites W2036265998 @default.
- W4220657582 cites W2041233786 @default.
- W4220657582 cites W2045385008 @default.
- W4220657582 cites W2045396403 @default.
- W4220657582 cites W2046081005 @default.
- W4220657582 cites W2048630989 @default.
- W4220657582 cites W2049779694 @default.
- W4220657582 cites W2051669119 @default.
- W4220657582 cites W2056849756 @default.
- W4220657582 cites W2059495112 @default.
- W4220657582 cites W2062440078 @default.
- W4220657582 cites W2063494976 @default.
- W4220657582 cites W2077586500 @default.
- W4220657582 cites W2092888368 @default.
- W4220657582 cites W2100391279 @default.
- W4220657582 cites W2101875696 @default.
- W4220657582 cites W2115147872 @default.
- W4220657582 cites W2129833491 @default.
- W4220657582 cites W2140985136 @default.
- W4220657582 cites W2141744996 @default.
- W4220657582 cites W2156487862 @default.
- W4220657582 cites W2165935023 @default.
- W4220657582 cites W2167575455 @default.
- W4220657582 cites W2208820319 @default.
- W4220657582 cites W2344409603 @default.
- W4220657582 cites W2405000978 @default.
- W4220657582 cites W2795984251 @default.
- W4220657582 cites W2799957635 @default.
- W4220657582 cites W2804535713 @default.
- W4220657582 cites W2887489666 @default.
- W4220657582 cites W2990071291 @default.
- W4220657582 cites W2990954496 @default.
- W4220657582 cites W2996350930 @default.
- W4220657582 cites W3006379979 @default.
- W4220657582 cites W3026056056 @default.
- W4220657582 cites W3118722267 @default.
- W4220657582 cites W3157290163 @default.
- W4220657582 cites W3185858999 @default.
- W4220657582 cites W3195963988 @default.
- W4220657582 cites W3214649305 @default.
- W4220657582 cites W4200227590 @default.
- W4220657582 cites W4210504863 @default.
- W4220657582 cites W574030711 @default.
- W4220657582 doi "https://doi.org/10.34215/1609-1175-2022-1-46-55" @default.
- W4220657582 hasPublicationYear "2022" @default.
- W4220657582 type Work @default.
- W4220657582 citedByCount "0" @default.
- W4220657582 crossrefType "journal-article" @default.
- W4220657582 hasAuthorship W4220657582A5022548458 @default.
- W4220657582 hasAuthorship W4220657582A5027651568 @default.
- W4220657582 hasAuthorship W4220657582A5051710909 @default.
- W4220657582 hasBestOaLocation W42206575821 @default.
- W4220657582 hasConcept C102230213 @default.
- W4220657582 hasConcept C104317684 @default.
- W4220657582 hasConcept C111599444 @default.
- W4220657582 hasConcept C159047783 @default.
- W4220657582 hasConcept C169760540 @default.
- W4220657582 hasConcept C2776878037 @default.
- W4220657582 hasConcept C2780384893 @default.
- W4220657582 hasConcept C32470452 @default.
- W4220657582 hasConcept C40767141 @default.
- W4220657582 hasConcept C54355233 @default.
- W4220657582 hasConcept C60644358 @default.
- W4220657582 hasConcept C70721500 @default.
- W4220657582 hasConcept C86803240 @default.