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- W4220683782 abstract "An atom-economical direct synthesis of carbazoles having aryl and aryl ketone groups has been achieved through Pd(II)-catalyzed cascade reactions between 1-(indol-2-yl)but-3-yn-1-ols and aldehydes. The reaction proceeds through alkyne-carbonyl metathesis, an uncommon pathway using palladium catalysts, and constitutes a fast intermolecular assembly through four carbon-carbon bond formations in one pot. Absence of the aldehyde substrate resulted in the formation of C4-aryl-substituted carbazoles. The reaction is amenable to the synthesis of biscarbazole derivatives." @default.
- W4220683782 created "2022-04-03" @default.
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- W4220683782 date "2022-03-07" @default.
- W4220683782 modified "2023-10-14" @default.
- W4220683782 title "Palladium-Catalyzed Benzannulations of 1-(Indol-2-yl)but-3-yn-1-ols: Easy Access to Functionalized Carbazoles" @default.
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- W4220683782 doi "https://doi.org/10.1021/acs.orglett.2c00182" @default.
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