Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220688003> ?p ?o ?g. }
- W4220688003 abstract "Glioma is the most common primary intracranial malignancy in the central nervous system. At present, the most important treatment option is surgical resection of the tumor combined with radiotherapy and chemotherapy. The principle of operation is to remove the tumor to the maximal extent on the basis of preserving brain function. However, prominent invasive and infiltrative proliferation of glioma tumor cells into the surrounding normal tissues frequently reduces the efficacy of treatment. This in turn worsens the prognosis, because the tumor cannot be completely removed, which can readily relapse. Chemotherapeutic agents when applied individually have demonstrated limited efficacy for the treatment of glioma. However, multiple different chemotherapeutic agents can be used in combination with other treatment modalities to improve the efficacy while circumventing systemic toxicity and drug resistance. Therefore, it is pivotal to unravel the inhibitory mechanism mediated by the different chemotherapeutic drugs on glioma cells in preclinical studies. The aim of the present review is to provide a summary for understanding the effects of different chemotherapeutic drugs in glioma, in addition to providing a reference for the preclinical research into novel chemotherapeutic agents for future clinical application." @default.
- W4220688003 created "2022-04-03" @default.
- W4220688003 creator A5029142865 @default.
- W4220688003 creator A5046597133 @default.
- W4220688003 creator A5054803735 @default.
- W4220688003 creator A5082038664 @default.
- W4220688003 creator A5086528871 @default.
- W4220688003 date "2022-03-30" @default.
- W4220688003 modified "2023-10-17" @default.
- W4220688003 title "Research progress of anti-glioma chemotherapeutic drugs (Review)" @default.
- W4220688003 cites W127705532 @default.
- W4220688003 cites W1841201983 @default.
- W4220688003 cites W1862775231 @default.
- W4220688003 cites W1901198588 @default.
- W4220688003 cites W1929868825 @default.
- W4220688003 cites W1984681580 @default.
- W4220688003 cites W2023928301 @default.
- W4220688003 cites W2026514919 @default.
- W4220688003 cites W2039816707 @default.
- W4220688003 cites W2042791872 @default.
- W4220688003 cites W2056753605 @default.
- W4220688003 cites W2074805250 @default.
- W4220688003 cites W2165451052 @default.
- W4220688003 cites W2172060759 @default.
- W4220688003 cites W2239268806 @default.
- W4220688003 cites W2280810829 @default.
- W4220688003 cites W2366536035 @default.
- W4220688003 cites W2490467724 @default.
- W4220688003 cites W2497577316 @default.
- W4220688003 cites W2531008215 @default.
- W4220688003 cites W2552171764 @default.
- W4220688003 cites W2594600378 @default.
- W4220688003 cites W2594625701 @default.
- W4220688003 cites W2607696196 @default.
- W4220688003 cites W2726265612 @default.
- W4220688003 cites W2740765687 @default.
- W4220688003 cites W2742701905 @default.
- W4220688003 cites W2746650126 @default.
- W4220688003 cites W2748092949 @default.
- W4220688003 cites W2773304535 @default.
- W4220688003 cites W2791657935 @default.
- W4220688003 cites W2801049857 @default.
- W4220688003 cites W2802299363 @default.
- W4220688003 cites W2807364687 @default.
- W4220688003 cites W2807770298 @default.
- W4220688003 cites W2884741638 @default.
- W4220688003 cites W2887387458 @default.
- W4220688003 cites W2896644327 @default.
- W4220688003 cites W2901720250 @default.
- W4220688003 cites W2902935766 @default.
- W4220688003 cites W2905250764 @default.
- W4220688003 cites W2906335608 @default.
- W4220688003 cites W2913046536 @default.
- W4220688003 cites W2914199948 @default.
- W4220688003 cites W2935821110 @default.
- W4220688003 cites W2938881653 @default.
- W4220688003 cites W2949310347 @default.
- W4220688003 cites W2950385063 @default.
- W4220688003 cites W2952362932 @default.
- W4220688003 cites W2954891553 @default.
- W4220688003 cites W2966347243 @default.
- W4220688003 cites W2968681394 @default.
- W4220688003 cites W2968722232 @default.
- W4220688003 cites W2968977249 @default.
- W4220688003 cites W2976309785 @default.
- W4220688003 cites W2978788085 @default.
- W4220688003 cites W2980467549 @default.
- W4220688003 cites W2983762161 @default.
- W4220688003 cites W2985447739 @default.
- W4220688003 cites W2993920415 @default.
- W4220688003 cites W2995725785 @default.
- W4220688003 cites W2996781333 @default.
- W4220688003 cites W2997516063 @default.
- W4220688003 cites W2999983497 @default.
- W4220688003 cites W3001307087 @default.
- W4220688003 cites W3002418857 @default.
- W4220688003 cites W3006718757 @default.
- W4220688003 cites W3010869929 @default.
- W4220688003 cites W3012959001 @default.
- W4220688003 cites W3022369570 @default.
- W4220688003 cites W3022915534 @default.
- W4220688003 cites W3023279101 @default.
- W4220688003 cites W3025211288 @default.
- W4220688003 cites W3031224726 @default.
- W4220688003 cites W3037578672 @default.
- W4220688003 cites W3041247161 @default.
- W4220688003 cites W3041918485 @default.
- W4220688003 cites W3042360629 @default.
- W4220688003 cites W3049669703 @default.
- W4220688003 cites W3079191246 @default.
- W4220688003 cites W3088559224 @default.
- W4220688003 cites W3088606085 @default.
- W4220688003 cites W3092018313 @default.
- W4220688003 cites W3092026074 @default.
- W4220688003 cites W3092435124 @default.
- W4220688003 cites W3095608911 @default.
- W4220688003 cites W3096115139 @default.
- W4220688003 cites W3096521890 @default.
- W4220688003 cites W3098895737 @default.
- W4220688003 cites W3114990296 @default.