FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220688751> ?p ?o ?g. }

• W4220688751 abstract "This study was conducted to evaluate the safety and efficacy of human peripheral blood CD34 positive (CD34+) cells transplanted into a murine chronic stroke model to obtain pre-clinical proof of concept, prior to clinical testing. Granulocyte colony stimulating factor (G-CSF) mobilized human CD34+ cells [1 × 104 cells in 50 μl phosphate-buffered saline (PBS)] were intravenously (iv) or intra-carotid arterially (ia) transplanted 4 weeks after the induction of stroke (chronic stage), and neurological function was evaluated. In this study, severe combined immune deficiency (SCID) mice were used to prevent excessive immune response after cell therapy. Two weeks post cell therapy, the ia CD34+ cells group demonstrated a significant improvement in neurological functions compared to the PBS control. The therapeutic effect was maintained 8 weeks after the treatment. Even after a single administration, ia transplantation of CD34+ cells had a significant therapeutic effect on chronic stroke. Based on the result of this pre-clinical proof of concept study, a future clinical trial of autologous peripheral blood CD34+ cells administration in the intra-carotid artery for chronic stroke patients is planned." @default.
• W4220688751 created "2022-04-03" @default.
• W4220688751 creator A5001677404 @default.
• W4220688751 creator A5011841792 @default.
• W4220688751 creator A5028365663 @default.
• W4220688751 creator A5030815223 @default.
• W4220688751 creator A5044882193 @default.
• W4220688751 creator A5055950674 @default.
• W4220688751 creator A5058056087 @default.
• W4220688751 creator A5063056494 @default.
• W4220688751 creator A5070584814 @default.
• W4220688751 creator A5075928055 @default.
• W4220688751 creator A5089399767 @default.
• W4220688751 date "2022-03-11" @default.
• W4220688751 modified "2023-10-14" @default.
• W4220688751 title "Pre-Clinical Proof of Concept: Intra-Carotid Injection of Autologous CD34-Positive Cells for Chronic Ischemic Stroke" @default.
• W4220688751 cites W2023447789 @default.
• W4220688751 cites W2053704719 @default.
• W4220688751 cites W2078947521 @default.
• W4220688751 cites W2095679806 @default.
• W4220688751 cites W2115399569 @default.
• W4220688751 cites W2145864353 @default.
• W4220688751 cites W2153531211 @default.
• W4220688751 cites W2157478807 @default.
• W4220688751 cites W2237017481 @default.
• W4220688751 cites W2340522258 @default.
• W4220688751 cites W2744822237 @default.
• W4220688751 cites W2886623777 @default.
• W4220688751 cites W2897734936 @default.
• W4220688751 cites W2902081282 @default.
• W4220688751 cites W2916940543 @default.
• W4220688751 cites W2946508262 @default.
• W4220688751 cites W2972895781 @default.
• W4220688751 cites W2982104105 @default.
• W4220688751 cites W3009037219 @default.
• W4220688751 cites W3022519346 @default.
• W4220688751 cites W3080599144 @default.
• W4220688751 cites W3108297901 @default.
• W4220688751 cites W3150640494 @default.
• W4220688751 cites W4254329016 @default.
• W4220688751 doi "https://doi.org/10.3389/fmed.2022.681316" @default.
• W4220688751 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35360717" @default.
• W4220688751 hasPublicationYear "2022" @default.
• W4220688751 type Work @default.
• W4220688751 citedByCount "2" @default.
• W4220688751 countsByYear W42206887512022 @default.
• W4220688751 countsByYear W42206887512023 @default.
• W4220688751 crossrefType "journal-article" @default.
• W4220688751 hasAuthorship W4220688751A5001677404 @default.
• W4220688751 hasAuthorship W4220688751A5011841792 @default.
• W4220688751 hasAuthorship W4220688751A5028365663 @default.
• W4220688751 hasAuthorship W4220688751A5030815223 @default.
• W4220688751 hasAuthorship W4220688751A5044882193 @default.
• W4220688751 hasAuthorship W4220688751A5055950674 @default.
• W4220688751 hasAuthorship W4220688751A5058056087 @default.
• W4220688751 hasAuthorship W4220688751A5063056494 @default.
• W4220688751 hasAuthorship W4220688751A5070584814 @default.
• W4220688751 hasAuthorship W4220688751A5075928055 @default.
• W4220688751 hasAuthorship W4220688751A5089399767 @default.
• W4220688751 hasBestOaLocation W42206887511 @default.
• W4220688751 hasConcept C10205521 @default.
• W4220688751 hasConcept C126322002 @default.
• W4220688751 hasConcept C127413603 @default.
• W4220688751 hasConcept C1862650 @default.
• W4220688751 hasConcept C203014093 @default.
• W4220688751 hasConcept C2776694085 @default.
• W4220688751 hasConcept C2777767877 @default.
• W4220688751 hasConcept C2778818304 @default.
• W4220688751 hasConcept C2780645631 @default.
• W4220688751 hasConcept C28328180 @default.
• W4220688751 hasConcept C2911091166 @default.
• W4220688751 hasConcept C3018579778 @default.
• W4220688751 hasConcept C535046627 @default.
• W4220688751 hasConcept C54355233 @default.
• W4220688751 hasConcept C71924100 @default.
• W4220688751 hasConcept C78519656 @default.
• W4220688751 hasConcept C86803240 @default.
• W4220688751 hasConcept C8891405 @default.
• W4220688751 hasConceptScore W4220688751C10205521 @default.
• W4220688751 hasConceptScore W4220688751C126322002 @default.
• W4220688751 hasConceptScore W4220688751C127413603 @default.
• W4220688751 hasConceptScore W4220688751C1862650 @default.
• W4220688751 hasConceptScore W4220688751C203014093 @default.
• W4220688751 hasConceptScore W4220688751C2776694085 @default.
• W4220688751 hasConceptScore W4220688751C2777767877 @default.
• W4220688751 hasConceptScore W4220688751C2778818304 @default.
• W4220688751 hasConceptScore W4220688751C2780645631 @default.
• W4220688751 hasConceptScore W4220688751C28328180 @default.
• W4220688751 hasConceptScore W4220688751C2911091166 @default.
• W4220688751 hasConceptScore W4220688751C3018579778 @default.
• W4220688751 hasConceptScore W4220688751C535046627 @default.
• W4220688751 hasConceptScore W4220688751C54355233 @default.
• W4220688751 hasConceptScore W4220688751C71924100 @default.
• W4220688751 hasConceptScore W4220688751C78519656 @default.
• W4220688751 hasConceptScore W4220688751C86803240 @default.
• W4220688751 hasConceptScore W4220688751C8891405 @default.
• W4220688751 hasLocation W42206887511 @default.
• W4220688751 hasLocation W42206887512 @default.
• W4220688751 hasLocation W42206887513 @default.
• W4220688751 hasLocation W42206887514 @default.

• next