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- W4220690850 abstract "In their natural habitats, populations of organisms are faced with different levels of chronic low-intensity radiation, causing a wide range of radiobiological effects (from radiosensitivity to radioadaptive response and hormesis). In this study, specimens of Drosophila melanogaster were selected from territories of the Chernobyl nuclear power plant with different levels of radioactive contamination. The isogenic stocks derived from these specimens represent the genetic systems of current populations and make it possible to study radioresistance and its mechanisms in future generations under controlled laboratory conditions. Previous studies have shown that transgenerational radiation effects at the level of lethal mutations and survival rate are unstable and depend not only on the level of chronic low-intensity irradiation, but also on other factors. A single acute irradiation exposure of offspring whose parents inhabited a site with a higher level of chronic irradiation made it possible to reveal pronounced radioresistant features in the offspring. And the offspring whose parents were exposed to radiation levels close to the natural radiation background, on the contrary, acquired radiosensitive features. Their response to acute exposure includes a high-frequency of lethal mutations and a short lifespan. The differential response to different levels of chronic parental exposure is caused by differences in the activities of certain transposons that destabilize the genome. Our data contribute to the understanding of genetic and epigenetic mechanisms (via transposon activity) of the effect of parental radiation exposure on the health and adaptive potential of populations affected by the technogenically increased radiation background." @default.
- W4220690850 created "2022-04-03" @default.
- W4220690850 creator A5049013305 @default.
- W4220690850 date "2022-02-01" @default.
- W4220690850 modified "2023-10-14" @default.
- W4220690850 title "Radiobiological features in offspring of natural populations of <scp><i>Drosophila melanogaster</i></scp> after Chernobyl accident" @default.
- W4220690850 cites W1482190741 @default.
- W4220690850 cites W1551573586 @default.
- W4220690850 cites W1599743869 @default.
- W4220690850 cites W1669658037 @default.
- W4220690850 cites W1916834316 @default.
- W4220690850 cites W1966413695 @default.
- W4220690850 cites W1975749767 @default.
- W4220690850 cites W1981913814 @default.
- W4220690850 cites W1983259076 @default.
- W4220690850 cites W1986588907 @default.
- W4220690850 cites W1989416640 @default.
- W4220690850 cites W1990654003 @default.
- W4220690850 cites W1995878525 @default.
- W4220690850 cites W1997280012 @default.
- W4220690850 cites W1999027330 @default.
- W4220690850 cites W1999572884 @default.
- W4220690850 cites W2006290617 @default.
- W4220690850 cites W2009478087 @default.
- W4220690850 cites W2030301369 @default.
- W4220690850 cites W2034158880 @default.
- W4220690850 cites W2037570580 @default.
- W4220690850 cites W2038720758 @default.
- W4220690850 cites W2043500928 @default.
- W4220690850 cites W2044505200 @default.
- W4220690850 cites W2044848085 @default.
- W4220690850 cites W2047313692 @default.
- W4220690850 cites W2051217983 @default.
- W4220690850 cites W2055913006 @default.
- W4220690850 cites W2057634033 @default.
- W4220690850 cites W2060911965 @default.
- W4220690850 cites W2066118199 @default.
- W4220690850 cites W2068909630 @default.
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- W4220690850 cites W2081403346 @default.
- W4220690850 cites W2088425357 @default.
- W4220690850 cites W2088717715 @default.
- W4220690850 cites W2095826979 @default.
- W4220690850 cites W2096196036 @default.
- W4220690850 cites W2097623820 @default.
- W4220690850 cites W2099658075 @default.
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- W4220690850 cites W2130451741 @default.
- W4220690850 cites W2146353326 @default.
- W4220690850 cites W2152222992 @default.
- W4220690850 cites W2153089127 @default.
- W4220690850 cites W2153991109 @default.
- W4220690850 cites W2162511779 @default.
- W4220690850 cites W2165512466 @default.
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- W4220690850 cites W2515386838 @default.
- W4220690850 cites W2530257681 @default.
- W4220690850 cites W2580016785 @default.
- W4220690850 cites W2740357871 @default.
- W4220690850 cites W2770829471 @default.
- W4220690850 cites W2789114815 @default.
- W4220690850 cites W2902145196 @default.
- W4220690850 cites W2905410339 @default.
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- W4220690850 cites W3008299879 @default.
- W4220690850 cites W3033621848 @default.
- W4220690850 cites W3108810221 @default.
- W4220690850 cites W3109421109 @default.
- W4220690850 cites W3133393321 @default.
- W4220690850 cites W3134808840 @default.
- W4220690850 cites W3135614337 @default.
- W4220690850 cites W3152595350 @default.
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- W4220690850 doi "https://doi.org/10.1002/em.22476" @default.
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