FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220698103> ?p ?o ?g. }

• W4220698103 abstract "Abstract Background Studies have shown that the optimal ischemia time (IT) threshold in pediatric heart transplantation (PHT) is up to 4 h, independent of other donor organ factors. The purpose of this study was to examine the relationship between IT and donor left ventricular ejection fraction (LVEF) and study their impact on PHT outcomes. Methods This is a retrospective cohort study of PHT (<18 years) identified in UNOS between January 2000 and March 2020. Post‐transplantation survival analysis of patients receiving donor hearts with IT<4, 4–6, and >6 h was performed using Kaplan–Meier curves. Cohort was divided according to donor LVEF median value, and survival was analyzed. Cox regression was performed. Results Median LVEF was 65% in the study cohort (6669 PHT). Overall, IT>6 h was associated with worse survival compared to <4 h regardless of donor LVEF. For allografts with LVEF < 65%, IT = 4–6 h was associated with worse survival compared with IT < 4 h ( p = .006) but had similar survival compared with IT > 6 h ( p = .315). For allografts with LVEF ≥ 65%, IT = 4–6 h had similar survival compared with <4 h ( p = .175) but improved survival compared with >6 h ( p = .003). After adjusting for donor and recipient variables, Cox regression showed that IT = 4–6 h was not associated with increased mortality for LVEF ≥ 65%. Conclusions The IT threshold of 4 h does not apply to all allografts. Recipients of hearts with LVEF≥65% can tolerate an IT up to 6 h without any detriment to survival. Routine acceptance of these donor hearts could mitigate longer waiting times and poor donor availability for many candidates." @default.
• W4220698103 created "2022-04-03" @default.
• W4220698103 creator A5018234203 @default.
• W4220698103 creator A5033519558 @default.
• W4220698103 creator A5035051474 @default.
• W4220698103 creator A5051977288 @default.
• W4220698103 creator A5053834656 @default.
• W4220698103 creator A5059247501 @default.
• W4220698103 creator A5061534057 @default.
• W4220698103 creator A5066799448 @default.
• W4220698103 creator A5070095313 @default.
• W4220698103 date "2022-03-08" @default.
• W4220698103 modified "2023-09-28" @default.
• W4220698103 title "Effect of ischemic time on pediatric heart transplantation outcomes: is it the same for all allografts?" @default.
• W4220698103 cites W1900499171 @default.
• W4220698103 cites W1981117979 @default.
• W4220698103 cites W2035508098 @default.
• W4220698103 cites W2116110519 @default.
• W4220698103 cites W2737796950 @default.
• W4220698103 cites W2755038465 @default.
• W4220698103 cites W2946305744 @default.
• W4220698103 cites W2967129829 @default.
• W4220698103 cites W2974237588 @default.
• W4220698103 cites W2993032871 @default.
• W4220698103 cites W3012773207 @default.
• W4220698103 cites W3043983343 @default.
• W4220698103 cites W3100542771 @default.
• W4220698103 cites W3110066057 @default.
• W4220698103 cites W3139181243 @default.
• W4220698103 cites W4235149067 @default.
• W4220698103 doi "https://doi.org/10.1111/petr.14259" @default.
• W4220698103 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35258159" @default.
• W4220698103 hasPublicationYear "2022" @default.
• W4220698103 type Work @default.
• W4220698103 citedByCount "1" @default.
• W4220698103 countsByYear W42206981032023 @default.
• W4220698103 crossrefType "journal-article" @default.
• W4220698103 hasAuthorship W4220698103A5018234203 @default.
• W4220698103 hasAuthorship W4220698103A5033519558 @default.
• W4220698103 hasAuthorship W4220698103A5035051474 @default.
• W4220698103 hasAuthorship W4220698103A5051977288 @default.
• W4220698103 hasAuthorship W4220698103A5053834656 @default.
• W4220698103 hasAuthorship W4220698103A5059247501 @default.
• W4220698103 hasAuthorship W4220698103A5061534057 @default.
• W4220698103 hasAuthorship W4220698103A5066799448 @default.
• W4220698103 hasAuthorship W4220698103A5070095313 @default.
• W4220698103 hasBestOaLocation W42206981032 @default.
• W4220698103 hasConcept C10515644 @default.
• W4220698103 hasConcept C126322002 @default.
• W4220698103 hasConcept C141071460 @default.
• W4220698103 hasConcept C164705383 @default.
• W4220698103 hasConcept C167135981 @default.
• W4220698103 hasConcept C201903717 @default.
• W4220698103 hasConcept C2778198053 @default.
• W4220698103 hasConcept C2778849806 @default.
• W4220698103 hasConcept C2911091166 @default.
• W4220698103 hasConcept C50382708 @default.
• W4220698103 hasConcept C71924100 @default.
• W4220698103 hasConcept C72563966 @default.
• W4220698103 hasConcept C78085059 @default.
• W4220698103 hasConceptScore W4220698103C10515644 @default.
• W4220698103 hasConceptScore W4220698103C126322002 @default.
• W4220698103 hasConceptScore W4220698103C141071460 @default.
• W4220698103 hasConceptScore W4220698103C164705383 @default.
• W4220698103 hasConceptScore W4220698103C167135981 @default.
• W4220698103 hasConceptScore W4220698103C201903717 @default.
• W4220698103 hasConceptScore W4220698103C2778198053 @default.
• W4220698103 hasConceptScore W4220698103C2778849806 @default.
• W4220698103 hasConceptScore W4220698103C2911091166 @default.
• W4220698103 hasConceptScore W4220698103C50382708 @default.
• W4220698103 hasConceptScore W4220698103C71924100 @default.
• W4220698103 hasConceptScore W4220698103C72563966 @default.
• W4220698103 hasConceptScore W4220698103C78085059 @default.
• W4220698103 hasFunder F4320332161 @default.
• W4220698103 hasIssue "4" @default.
• W4220698103 hasLocation W42206981031 @default.
• W4220698103 hasLocation W42206981032 @default.
• W4220698103 hasLocation W42206981033 @default.
• W4220698103 hasOpenAccess W4220698103 @default.
• W4220698103 hasPrimaryLocation W42206981031 @default.
• W4220698103 hasRelatedWork W131145841 @default.
• W4220698103 hasRelatedWork W1971557041 @default.
• W4220698103 hasRelatedWork W2012624239 @default.
• W4220698103 hasRelatedWork W2345822668 @default.
• W4220698103 hasRelatedWork W2896288599 @default.
• W4220698103 hasRelatedWork W3110151069 @default.
• W4220698103 hasRelatedWork W3193919628 @default.
• W4220698103 hasRelatedWork W3197836132 @default.
• W4220698103 hasRelatedWork W4210782677 @default.
• W4220698103 hasRelatedWork W4220698103 @default.
• W4220698103 hasVolume "26" @default.
• W4220698103 isParatext "false" @default.
• W4220698103 isRetracted "false" @default.
• W4220698103 workType "article" @default.