Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220705110> ?p ?o ?g. }
- W4220705110 endingPage "100055" @default.
- W4220705110 startingPage "100055" @default.
- W4220705110 abstract "Cellular functions rely on proper actions of organelles such as peroxisomes. These organelles rely on the import of proteins from the cytosol. The peroxisomal import receptor PEX5 takes up target proteins in the cytosol and transports them to the peroxisomal matrix. However, its cytosolic molecular interactions have so far not directly been disclosed. Here, we combined advanced optical microscopy and spectroscopy techniques such as fluorescence correlation spectroscopy and stimulated emission depletion microscopy with biochemical tools to present a detailed characterization of the cytosolic diffusion and interaction dynamics of PEX5. Among other features, we highlight a slow diffusion of PEX5, independent of aggregation or target binding, but associated with cytosolic interaction partners via its N-terminal domain. This sheds new light on the functionality of the receptor in the cytosol as well as highlighting the potential of using complementary microscopy tools to decipher molecular interactions in the cytosol by studying their diffusion dynamics." @default.
- W4220705110 created "2022-04-03" @default.
- W4220705110 creator A5002316926 @default.
- W4220705110 creator A5003273955 @default.
- W4220705110 creator A5004121317 @default.
- W4220705110 creator A5005948924 @default.
- W4220705110 creator A5010243173 @default.
- W4220705110 creator A5012995576 @default.
- W4220705110 creator A5018474916 @default.
- W4220705110 creator A5037710435 @default.
- W4220705110 creator A5046989784 @default.
- W4220705110 creator A5058514738 @default.
- W4220705110 creator A5060590095 @default.
- W4220705110 creator A5067170740 @default.
- W4220705110 creator A5067171744 @default.
- W4220705110 creator A5069417812 @default.
- W4220705110 date "2022-06-01" @default.
- W4220705110 modified "2023-10-17" @default.
- W4220705110 title "Diffusion and interaction dynamics of the cytosolic peroxisomal import receptor PEX5" @default.
- W4220705110 cites W1563083583 @default.
- W4220705110 cites W1665694733 @default.
- W4220705110 cites W1963667377 @default.
- W4220705110 cites W1967503648 @default.
- W4220705110 cites W1970650210 @default.
- W4220705110 cites W1972000963 @default.
- W4220705110 cites W1972234131 @default.
- W4220705110 cites W1972387348 @default.
- W4220705110 cites W1981277012 @default.
- W4220705110 cites W1981916955 @default.
- W4220705110 cites W2003654187 @default.
- W4220705110 cites W2007209781 @default.
- W4220705110 cites W2008453524 @default.
- W4220705110 cites W2009917506 @default.
- W4220705110 cites W2010309369 @default.
- W4220705110 cites W2013990977 @default.
- W4220705110 cites W2017038627 @default.
- W4220705110 cites W2021882008 @default.
- W4220705110 cites W2022393754 @default.
- W4220705110 cites W2023736718 @default.
- W4220705110 cites W2035829259 @default.
- W4220705110 cites W2036035257 @default.
- W4220705110 cites W2046856915 @default.
- W4220705110 cites W2047483253 @default.
- W4220705110 cites W2050410337 @default.
- W4220705110 cites W2059807927 @default.
- W4220705110 cites W2068237765 @default.
- W4220705110 cites W2072145578 @default.
- W4220705110 cites W2079997146 @default.
- W4220705110 cites W2080392944 @default.
- W4220705110 cites W2086782515 @default.
- W4220705110 cites W2092591295 @default.
- W4220705110 cites W2094395140 @default.
- W4220705110 cites W2096046762 @default.
- W4220705110 cites W2097711273 @default.
- W4220705110 cites W2101218774 @default.
- W4220705110 cites W2103186456 @default.
- W4220705110 cites W2103944364 @default.
- W4220705110 cites W2106573607 @default.
- W4220705110 cites W2110427436 @default.
- W4220705110 cites W2112524464 @default.
- W4220705110 cites W2115449551 @default.
- W4220705110 cites W2116382310 @default.
- W4220705110 cites W2126833322 @default.
- W4220705110 cites W2134867392 @default.
- W4220705110 cites W2146795350 @default.
- W4220705110 cites W2164565944 @default.
- W4220705110 cites W2177040883 @default.
- W4220705110 cites W2433308867 @default.
- W4220705110 cites W2461013690 @default.
- W4220705110 cites W2476984584 @default.
- W4220705110 cites W2582285661 @default.
- W4220705110 cites W2605759836 @default.
- W4220705110 cites W2729283896 @default.
- W4220705110 cites W2770289895 @default.
- W4220705110 cites W2789851401 @default.
- W4220705110 cites W2883254430 @default.
- W4220705110 cites W2920613080 @default.
- W4220705110 cites W2965827670 @default.
- W4220705110 cites W3002252366 @default.
- W4220705110 cites W3004007146 @default.
- W4220705110 cites W3045939944 @default.
- W4220705110 cites W3113201765 @default.
- W4220705110 cites W4243791482 @default.
- W4220705110 doi "https://doi.org/10.1016/j.bpr.2022.100055" @default.
- W4220705110 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36299769" @default.
- W4220705110 hasPublicationYear "2022" @default.
- W4220705110 type Work @default.
- W4220705110 citedByCount "3" @default.
- W4220705110 countsByYear W42207051102022 @default.
- W4220705110 countsByYear W42207051102023 @default.
- W4220705110 crossrefType "journal-article" @default.
- W4220705110 hasAuthorship W4220705110A5002316926 @default.
- W4220705110 hasAuthorship W4220705110A5003273955 @default.
- W4220705110 hasAuthorship W4220705110A5004121317 @default.
- W4220705110 hasAuthorship W4220705110A5005948924 @default.
- W4220705110 hasAuthorship W4220705110A5010243173 @default.
- W4220705110 hasAuthorship W4220705110A5012995576 @default.
- W4220705110 hasAuthorship W4220705110A5018474916 @default.