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- W4220705945 abstract "HTLV-1 is a retrovirus that has an impact on human health due to its T-lymphocyte tropism. It occurs worldwide, but is more prevalent in tropical regions. Although most infected individuals will remain asymptomatic, the infection may manifest with complications such as uveitis, myelopathy, and leukemia, among others. The diagnosis is achieved by the detection of anti-HTLV antibodies and a confirmatory test (Western Blot or proviral load). Although there is no specific treatment, medical treatments are aimed towards the management of secondary diseases. Three cases are described of pediatric patients diagnosed with HTLV-1 infection and associated autoimmune manifestations. El HTLV-1 es un retrovirus que causa impacto en la salud del ser humano, debido al tropismo para infectar a linfocitos T. Está distribuido mundialmente, pero es más prevalente en regiones tropicales. La mayoría de las personas afectadas permanecen asintomáticas, sin embargo, al manifestarse puede causar complicaciones como uveítis, mielopatía, leucemia, entre otras. Su diagnóstico se hace mediante la determinación de anticuerpos anti-HTLV y prueba confirmatoria (Western Blot o carga proviral). No tiene tratamiento específico, las medidas están dirigidas a la prevención y el manejo de las patologías secundarias. Se describen tres pacientes en edad pediátrica con diagnóstico de infección por HTLV-1 y manifestaciones autoinmunes." @default.
- W4220705945 created "2022-04-03" @default.
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- W4220705945 date "2022-03-01" @default.
- W4220705945 modified "2023-10-14" @default.
- W4220705945 title "Autoimmune manifestations in pediatric patients with human type I T - cell lymphotropic virus (HTLV-1) infection" @default.
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- W4220705945 doi "https://doi.org/10.1016/j.rcreue.2022.02.001" @default.
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