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• W4220713099 abstract "Abstract To provide novel data on surfactant levels in adult COVID-19 patients, we collected bronchoalveolar lavage fluid less than 72 h after intubation and used Fourier Transform Infrared Spectroscopy to measure levels of dipalmitoylphosphatidylcholine (DPPC). A total of eleven COVID-19 patients with moderate-to-severe ARDS (CARDS) and 15 healthy controls were included. CARDS patients had lower DPPC levels than healthy controls. Moreover, a principal component analysis was able to separate patient groups into distinguishable subgroups. Our findings indicate markedly impaired pulmonary surfactant levels in COVID-19 patients, justifying further studies and clinical trials of exogenous surfactant." @default.
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• W4220713099 date "2022-03-08" @default.
• W4220713099 modified "2023-10-01" @default.
• W4220713099 title "Reduced levels of pulmonary surfactant in COVID-19 ARDS" @default.
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• W4220713099 doi "https://doi.org/10.1038/s41598-022-07944-4" @default.
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