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- W4220720462 abstract "Abstract Dietary polyphenols interact with glucose transporters in the small intestine and modulate glucose uptake after food or beverage consumption. This review assesses the transporter interaction in vitro and how this translates to an effect in healthy volunteers consuming glucose. As examples, the apple polyphenol phlorizin inhibits sodium‐glucose linked transporter‐1; in the intestinal lumen, it is converted to phloretin, a strong inhibitor of glucose transporter‐2 (GLUT2), by the brush border digestive enzyme lactase. Consequently, an apple extract rich in phlorizin attenuates blood glucose and insulin in healthy volunteers after a glucose challenge. On the other hand, the olive phenolic, oleuropein, inhibits GLUT2, but the strength of the inhibition is not enough to modulate blood glucose after a glucose challenge in healthy volunteers. Multiple metabolic effects and oxidative stresses after glucose consumption include insulin, incretin hormones, fatty acids, amino acids, and protein markers. However, apart from acute postprandial effects on glucose, insulin, and some incretin hormones, very little is known about the acute effects of polyphenols on these glucose‐induced secondary effects. In summary, attenuation of the effect of a glucose challenge in vivo is only observed when polyphenols are strong inhibitors of glucose transporters." @default.
- W4220720462 created "2022-04-03" @default.
- W4220720462 creator A5020427938 @default.
- W4220720462 date "2022-04-06" @default.
- W4220720462 modified "2023-10-18" @default.
- W4220720462 title "Effects of Polyphenols on Glucose‐Induced Metabolic Changes in Healthy Human Subjects and on Glucose Transporters" @default.
- W4220720462 cites W1263404949 @default.
- W4220720462 cites W1596027997 @default.
- W4220720462 cites W1704599202 @default.
- W4220720462 cites W1846125448 @default.
- W4220720462 cites W1895964898 @default.
- W4220720462 cites W1911623996 @default.
- W4220720462 cites W1914622032 @default.
- W4220720462 cites W1960608858 @default.
- W4220720462 cites W1965075210 @default.
- W4220720462 cites W1968569204 @default.
- W4220720462 cites W1977106726 @default.
- W4220720462 cites W1987891029 @default.
- W4220720462 cites W1997363455 @default.
- W4220720462 cites W2000118672 @default.
- W4220720462 cites W2004499066 @default.
- W4220720462 cites W2007005354 @default.
- W4220720462 cites W2008095387 @default.
- W4220720462 cites W2011470760 @default.
- W4220720462 cites W2014307058 @default.
- W4220720462 cites W2015977579 @default.
- W4220720462 cites W2016968130 @default.
- W4220720462 cites W2020187222 @default.
- W4220720462 cites W2020590713 @default.
- W4220720462 cites W2023995851 @default.
- W4220720462 cites W2032110401 @default.
- W4220720462 cites W2038343564 @default.
- W4220720462 cites W2043239337 @default.
- W4220720462 cites W2062552036 @default.
- W4220720462 cites W2066129630 @default.
- W4220720462 cites W2066246982 @default.
- W4220720462 cites W2072729323 @default.
- W4220720462 cites W2074399756 @default.
- W4220720462 cites W2109132990 @default.
- W4220720462 cites W2113253151 @default.
- W4220720462 cites W2118683198 @default.
- W4220720462 cites W2120537924 @default.
- W4220720462 cites W2125299541 @default.
- W4220720462 cites W2133604166 @default.
- W4220720462 cites W2133795831 @default.
- W4220720462 cites W2134948484 @default.
- W4220720462 cites W2143699322 @default.
- W4220720462 cites W2146947016 @default.
- W4220720462 cites W2151356634 @default.
- W4220720462 cites W2153030555 @default.
- W4220720462 cites W2159003260 @default.
- W4220720462 cites W2162766318 @default.
- W4220720462 cites W2166283593 @default.
- W4220720462 cites W2168552382 @default.
- W4220720462 cites W2170276146 @default.
- W4220720462 cites W2171071347 @default.
- W4220720462 cites W2223868498 @default.
- W4220720462 cites W2227252279 @default.
- W4220720462 cites W2473615084 @default.
- W4220720462 cites W2524253341 @default.
- W4220720462 cites W2545048640 @default.
- W4220720462 cites W2753396088 @default.
- W4220720462 cites W2761683484 @default.
- W4220720462 cites W2768017343 @default.
- W4220720462 cites W2791975045 @default.
- W4220720462 cites W2792521254 @default.
- W4220720462 cites W2802590465 @default.
- W4220720462 cites W2857010441 @default.
- W4220720462 cites W2890622265 @default.
- W4220720462 cites W2912390090 @default.
- W4220720462 cites W2914095780 @default.
- W4220720462 cites W2920884286 @default.
- W4220720462 cites W2939928664 @default.
- W4220720462 cites W2944345687 @default.
- W4220720462 cites W2968819243 @default.
- W4220720462 cites W2989926507 @default.
- W4220720462 cites W2989943484 @default.
- W4220720462 cites W3006227237 @default.
- W4220720462 cites W3028895871 @default.
- W4220720462 cites W3081351755 @default.
- W4220720462 cites W3087172481 @default.
- W4220720462 cites W3093367767 @default.
- W4220720462 cites W3096033699 @default.
- W4220720462 cites W3120651611 @default.
- W4220720462 cites W3157971819 @default.
- W4220720462 cites W3194044852 @default.
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- W4220720462 doi "https://doi.org/10.1002/mnfr.202101113" @default.
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