Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220738314> ?p ?o ?g. }
- W4220738314 endingPage "1976" @default.
- W4220738314 startingPage "1964" @default.
- W4220738314 abstract "The metabolic potential of the sulfate-reducing bacterium Desulfosarcina sp. strain BuS5, currently the only pure culture able to oxidize the volatile alkanes propane and butane without oxygen, was investigated via genomics, proteomics and physiology assays. Complete genome sequencing revealed that strain BuS5 encodes a single alkyl-succinate synthase, an enzyme which apparently initiates oxidation of both propane and butane. The formed alkyl-succinates are oxidized to CO2 via beta oxidation and the oxidative Wood-Ljungdahl pathways as shown by proteogenomics analyses. Strain BuS5 conserves energy via the canonical sulfate reduction pathway and electron bifurcation. An ability to utilize long-chain fatty acids, mannose and oligopeptides, suggested by automated annotation pipelines, was not supported by physiology assays and in-depth analyses of the corresponding genetic systems. Consistently, comparative genomics revealed a streamlined BuS5 genome with a remarkable paucity of catabolic modules. These results establish strain BuS5 as an exceptional metabolic specialist, able to grow only with propane and butane, for which we propose the name Desulfosarcina aeriophaga BuS5. This highly restrictive lifestyle, most likely the result of habitat-driven evolutionary gene loss, may provide D. aeriophaga BuS5 a competitive edge in sediments impacted by natural gas seeps. Etymology: Desulfosarcina aeriophaga, aério (Greek): gas; phágos (Greek): eater; D. aeriophaga: a gas eating or gas feeding Desulfosarcina." @default.
- W4220738314 created "2022-04-03" @default.
- W4220738314 creator A5001556566 @default.
- W4220738314 creator A5029012645 @default.
- W4220738314 creator A5047264689 @default.
- W4220738314 creator A5049497236 @default.
- W4220738314 creator A5054349171 @default.
- W4220738314 creator A5058663342 @default.
- W4220738314 creator A5064091369 @default.
- W4220738314 date "2022-03-07" @default.
- W4220738314 modified "2023-10-15" @default.
- W4220738314 title "Genome and proteome analyses show the gaseous alkane degrader <i>Desulfosarcina</i> sp. strain <scp>BuS5</scp> as an extreme metabolic specialist" @default.
- W4220738314 cites W1483400313 @default.
- W4220738314 cites W1542216447 @default.
- W4220738314 cites W1567991226 @default.
- W4220738314 cites W1768003754 @default.
- W4220738314 cites W1919969142 @default.
- W4220738314 cites W1965488364 @default.
- W4220738314 cites W1968978338 @default.
- W4220738314 cites W1976317980 @default.
- W4220738314 cites W1979939707 @default.
- W4220738314 cites W1981658991 @default.
- W4220738314 cites W1990334594 @default.
- W4220738314 cites W1996423252 @default.
- W4220738314 cites W2001834053 @default.
- W4220738314 cites W2007541497 @default.
- W4220738314 cites W2012402138 @default.
- W4220738314 cites W2014080563 @default.
- W4220738314 cites W2027133863 @default.
- W4220738314 cites W2036752092 @default.
- W4220738314 cites W2037798583 @default.
- W4220738314 cites W2044266543 @default.
- W4220738314 cites W2045843097 @default.
- W4220738314 cites W2050687478 @default.
- W4220738314 cites W2051266642 @default.
- W4220738314 cites W2065566884 @default.
- W4220738314 cites W2079217126 @default.
- W4220738314 cites W2081607933 @default.
- W4220738314 cites W2084464247 @default.
- W4220738314 cites W2087923912 @default.
- W4220738314 cites W2095641347 @default.
- W4220738314 cites W2097198628 @default.
- W4220738314 cites W2102104442 @default.
- W4220738314 cites W2102652793 @default.
- W4220738314 cites W2115888213 @default.
- W4220738314 cites W2119903045 @default.
- W4220738314 cites W2122550654 @default.
- W4220738314 cites W2124432551 @default.
- W4220738314 cites W2124862585 @default.
- W4220738314 cites W2130105490 @default.
- W4220738314 cites W2134420054 @default.
- W4220738314 cites W2138537589 @default.
- W4220738314 cites W2140953593 @default.
- W4220738314 cites W2141052558 @default.
- W4220738314 cites W2142678478 @default.
- W4220738314 cites W2143162014 @default.
- W4220738314 cites W2143485490 @default.
- W4220738314 cites W2147352039 @default.
- W4220738314 cites W2147838577 @default.
- W4220738314 cites W2155130127 @default.
- W4220738314 cites W2155302505 @default.
- W4220738314 cites W2159268740 @default.
- W4220738314 cites W2159609616 @default.
- W4220738314 cites W2160378127 @default.
- W4220738314 cites W2162879785 @default.
- W4220738314 cites W2163503178 @default.
- W4220738314 cites W2171179107 @default.
- W4220738314 cites W2171770091 @default.
- W4220738314 cites W2215148870 @default.
- W4220738314 cites W2294705018 @default.
- W4220738314 cites W2340816894 @default.
- W4220738314 cites W2530145839 @default.
- W4220738314 cites W2556499687 @default.
- W4220738314 cites W2559588208 @default.
- W4220738314 cites W2726257503 @default.
- W4220738314 cites W2748451004 @default.
- W4220738314 cites W2766358903 @default.
- W4220738314 cites W2803245377 @default.
- W4220738314 cites W2804023169 @default.
- W4220738314 cites W2806928302 @default.
- W4220738314 cites W2807812207 @default.
- W4220738314 cites W2809137787 @default.
- W4220738314 cites W2887454799 @default.
- W4220738314 cites W2900629010 @default.
- W4220738314 cites W2922604047 @default.
- W4220738314 cites W2925028102 @default.
- W4220738314 cites W2939753925 @default.
- W4220738314 cites W2941342985 @default.
- W4220738314 cites W2947169917 @default.
- W4220738314 cites W2952167528 @default.
- W4220738314 cites W2986925300 @default.
- W4220738314 cites W2999440043 @default.
- W4220738314 cites W3016503030 @default.
- W4220738314 cites W3037178070 @default.
- W4220738314 cites W3095583226 @default.
- W4220738314 cites W3136918052 @default.
- W4220738314 cites W3213112570 @default.
- W4220738314 cites W4205550164 @default.