FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220740923> ?p ?o ?g. }

• W4220740923 endingPage "490" @default.
• W4220740923 startingPage "483" @default.
• W4220740923 abstract "Differentiation protocols are used for induced pluripotent stem cells (iPSCs) in in vitro disease modeling and clinical applications. Transplantation of endothelial cells (ECs) is an important treatment strategy for ischemic diseases. For example, in vitro generated ECs can be used to provide the vascular plexus to regenerate organs such as the liver. Here, we demonstrate that the E-twenty-six (ETS) transcription factor ETV2 alone can directly convert iPSCs into vascular endothelial cells (iPS-ETV2-ECs) with an efficiency of over 90% within 5 d. Although the stable overexpression of ETV2 induced the expression of multiple key factors for endothelial development, the induced ECs were less mature. Furthermore, doxycycline-inducible transient ETV2 expression could upregulate the expression of von Willebrand factor (vWF) in iPS-ETV2-ECs, leading to a mature phenotype. The findings of this study on generation of mature iPS-ETV2-ECs provide further insights into the exploration of cell reprogramming from iPSCs. Here, we provide a new protocol for differentiation of iPSCs, thus providing a new source of ECs for in vitro disease modeling and clinical applications." @default.
• W4220740923 created "2022-04-03" @default.
• W4220740923 creator A5029199190 @default.
• W4220740923 creator A5042675351 @default.
• W4220740923 creator A5079742854 @default.
• W4220740923 creator A5090897268 @default.
• W4220740923 date "2022-04-01" @default.
• W4220740923 modified "2023-10-17" @default.
• W4220740923 title "Transient ETV2 Expression Promotes the Generation of Mature Endothelial Cells from Human Pluripotent Stem Cells" @default.
• W4220740923 cites W1965378998 @default.
• W4220740923 cites W1966018836 @default.
• W4220740923 cites W1976212341 @default.
• W4220740923 cites W1999579644 @default.
• W4220740923 cites W2001726213 @default.
• W4220740923 cites W2004445343 @default.
• W4220740923 cites W2011747072 @default.
• W4220740923 cites W2019724225 @default.
• W4220740923 cites W2021495513 @default.
• W4220740923 cites W2022522122 @default.
• W4220740923 cites W2030406511 @default.
• W4220740923 cites W2030414936 @default.
• W4220740923 cites W2031632681 @default.
• W4220740923 cites W2049466721 @default.
• W4220740923 cites W2053704719 @default.
• W4220740923 cites W2065561114 @default.
• W4220740923 cites W2082664445 @default.
• W4220740923 cites W2111301327 @default.
• W4220740923 cites W2121288046 @default.
• W4220740923 cites W2128876415 @default.
• W4220740923 cites W2129206121 @default.
• W4220740923 cites W2129396577 @default.
• W4220740923 cites W2138977668 @default.
• W4220740923 cites W2142046859 @default.
• W4220740923 cites W2153667577 @default.
• W4220740923 cites W2197971027 @default.
• W4220740923 cites W2253553499 @default.
• W4220740923 cites W2380741403 @default.
• W4220740923 cites W2565065629 @default.
• W4220740923 cites W2593871081 @default.
• W4220740923 cites W2899234772 @default.
• W4220740923 cites W2989951181 @default.
• W4220740923 cites W4249346427 @default.
• W4220740923 cites W84556570 @default.
• W4220740923 doi "https://doi.org/10.1248/bpb.b21-00929" @default.
• W4220740923 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35370273" @default.
• W4220740923 hasPublicationYear "2022" @default.
• W4220740923 type Work @default.
• W4220740923 citedByCount "2" @default.
• W4220740923 countsByYear W42207409232023 @default.
• W4220740923 crossrefType "journal-article" @default.
• W4220740923 hasAuthorship W4220740923A5029199190 @default.
• W4220740923 hasAuthorship W4220740923A5042675351 @default.
• W4220740923 hasAuthorship W4220740923A5079742854 @default.
• W4220740923 hasAuthorship W4220740923A5090897268 @default.
• W4220740923 hasBestOaLocation W42207409231 @default.
• W4220740923 hasConcept C104317684 @default.
• W4220740923 hasConcept C107459253 @default.
• W4220740923 hasConcept C123012128 @default.
• W4220740923 hasConcept C141071460 @default.
• W4220740923 hasConcept C145103041 @default.
• W4220740923 hasConcept C148738053 @default.
• W4220740923 hasConcept C1491633281 @default.
• W4220740923 hasConcept C202751555 @default.
• W4220740923 hasConcept C203014093 @default.
• W4220740923 hasConcept C2911091166 @default.
• W4220740923 hasConcept C502942594 @default.
• W4220740923 hasConcept C54355233 @default.
• W4220740923 hasConcept C71924100 @default.
• W4220740923 hasConcept C77255625 @default.
• W4220740923 hasConcept C86339819 @default.
• W4220740923 hasConcept C86803240 @default.
• W4220740923 hasConcept C95444343 @default.
• W4220740923 hasConceptScore W4220740923C104317684 @default.
• W4220740923 hasConceptScore W4220740923C107459253 @default.
• W4220740923 hasConceptScore W4220740923C123012128 @default.
• W4220740923 hasConceptScore W4220740923C141071460 @default.
• W4220740923 hasConceptScore W4220740923C145103041 @default.
• W4220740923 hasConceptScore W4220740923C148738053 @default.
• W4220740923 hasConceptScore W4220740923C1491633281 @default.
• W4220740923 hasConceptScore W4220740923C202751555 @default.
• W4220740923 hasConceptScore W4220740923C203014093 @default.
• W4220740923 hasConceptScore W4220740923C2911091166 @default.
• W4220740923 hasConceptScore W4220740923C502942594 @default.
• W4220740923 hasConceptScore W4220740923C54355233 @default.
• W4220740923 hasConceptScore W4220740923C71924100 @default.
• W4220740923 hasConceptScore W4220740923C77255625 @default.
• W4220740923 hasConceptScore W4220740923C86339819 @default.
• W4220740923 hasConceptScore W4220740923C86803240 @default.
• W4220740923 hasConceptScore W4220740923C95444343 @default.
• W4220740923 hasIssue "4" @default.
• W4220740923 hasLocation W42207409231 @default.
• W4220740923 hasLocation W42207409232 @default.
• W4220740923 hasOpenAccess W4220740923 @default.
• W4220740923 hasPrimaryLocation W42207409231 @default.
• W4220740923 hasRelatedWork W2021894633 @default.
• W4220740923 hasRelatedWork W2047597126 @default.
• W4220740923 hasRelatedWork W2058458809 @default.
• W4220740923 hasRelatedWork W2212856550 @default.

• next