Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220740991> ?p ?o ?g. }
- W4220740991 endingPage "127" @default.
- W4220740991 startingPage "117" @default.
- W4220740991 abstract "Messenger RNA (mRNA) has recently made important progress in clinical implementation, offering a promising therapeutic option for infectious disease and cancer. However, the nature of mRNA molecules rendered them poorly bioavailable and unstable in vivo, impeding their further clinical application. Therefore, safe and efficient delivery of mRNA therapeutics to the target site is crucial for their successful translation into the clinical setting. Various vectors have been explored for mRNA delivery. Among them, polyesters and their analogs, a family of biodegradable polymers, have exhibited great potential for mRNA delivery. In this short review, the authors briefly introduce mRNA therapeutics, their therapeutic applications and delivery challenges. The authors then presented the typical examples of polyester materials for mRNA delivery to highlight the current progress and discuss the challenges for the rational design of polyester based mRNA delivery vectors. The authors hope to provide a new insight for the design of biodegradable vectors for nucleic acids delivery, thereby promoting their further clinic translation." @default.
- W4220740991 created "2022-04-03" @default.
- W4220740991 creator A5009658608 @default.
- W4220740991 creator A5027307547 @default.
- W4220740991 creator A5033030924 @default.
- W4220740991 creator A5077737058 @default.
- W4220740991 date "2022-03-11" @default.
- W4220740991 modified "2023-10-14" @default.
- W4220740991 title "Polyester materials for mRNA delivery" @default.
- W4220740991 cites W1963706689 @default.
- W4220740991 cites W1966865009 @default.
- W4220740991 cites W2004180909 @default.
- W4220740991 cites W2014495927 @default.
- W4220740991 cites W2014509855 @default.
- W4220740991 cites W2039357236 @default.
- W4220740991 cites W2039551908 @default.
- W4220740991 cites W2043026814 @default.
- W4220740991 cites W2077364459 @default.
- W4220740991 cites W2091548845 @default.
- W4220740991 cites W2102797150 @default.
- W4220740991 cites W2106014350 @default.
- W4220740991 cites W2122562716 @default.
- W4220740991 cites W2208560199 @default.
- W4220740991 cites W2525553968 @default.
- W4220740991 cites W2570278065 @default.
- W4220740991 cites W2573033399 @default.
- W4220740991 cites W2754401101 @default.
- W4220740991 cites W2770318482 @default.
- W4220740991 cites W2782708334 @default.
- W4220740991 cites W2801310804 @default.
- W4220740991 cites W2804073175 @default.
- W4220740991 cites W2808372952 @default.
- W4220740991 cites W2809044246 @default.
- W4220740991 cites W2889908254 @default.
- W4220740991 cites W2891634798 @default.
- W4220740991 cites W2893538598 @default.
- W4220740991 cites W2905923727 @default.
- W4220740991 cites W2907167357 @default.
- W4220740991 cites W2916319300 @default.
- W4220740991 cites W2945045272 @default.
- W4220740991 cites W3004131145 @default.
- W4220740991 cites W3007447370 @default.
- W4220740991 cites W3035225041 @default.
- W4220740991 cites W3043327933 @default.
- W4220740991 cites W3044226803 @default.
- W4220740991 cites W3118959850 @default.
- W4220740991 cites W3121264726 @default.
- W4220740991 cites W3122312485 @default.
- W4220740991 cites W3130729977 @default.
- W4220740991 cites W3138779485 @default.
- W4220740991 cites W3155812023 @default.
- W4220740991 cites W3158625784 @default.
- W4220740991 cites W3173264505 @default.
- W4220740991 cites W3177445623 @default.
- W4220740991 cites W3184644021 @default.
- W4220740991 cites W3188940990 @default.
- W4220740991 cites W3193427089 @default.
- W4220740991 cites W3195360371 @default.
- W4220740991 cites W3196420132 @default.
- W4220740991 cites W3198244112 @default.
- W4220740991 cites W4200069835 @default.
- W4220740991 cites W4200475508 @default.
- W4220740991 doi "https://doi.org/10.37349/etat.2022.00075" @default.
- W4220740991 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36046844" @default.
- W4220740991 hasPublicationYear "2022" @default.
- W4220740991 type Work @default.
- W4220740991 citedByCount "1" @default.
- W4220740991 countsByYear W42207409912022 @default.
- W4220740991 crossrefType "journal-article" @default.
- W4220740991 hasAuthorship W4220740991A5009658608 @default.
- W4220740991 hasAuthorship W4220740991A5027307547 @default.
- W4220740991 hasAuthorship W4220740991A5033030924 @default.
- W4220740991 hasAuthorship W4220740991A5077737058 @default.
- W4220740991 hasBestOaLocation W42207409911 @default.
- W4220740991 hasConcept C104317684 @default.
- W4220740991 hasConcept C105580179 @default.
- W4220740991 hasConcept C119394753 @default.
- W4220740991 hasConcept C149364088 @default.
- W4220740991 hasConcept C150903083 @default.
- W4220740991 hasConcept C171250308 @default.
- W4220740991 hasConcept C178790620 @default.
- W4220740991 hasConcept C185592680 @default.
- W4220740991 hasConcept C192562407 @default.
- W4220740991 hasConcept C207001950 @default.
- W4220740991 hasConcept C24107716 @default.
- W4220740991 hasConcept C2983812674 @default.
- W4220740991 hasConcept C55493867 @default.
- W4220740991 hasConcept C67705224 @default.
- W4220740991 hasConcept C70721500 @default.
- W4220740991 hasConcept C86803240 @default.
- W4220740991 hasConcept C98274493 @default.
- W4220740991 hasConceptScore W4220740991C104317684 @default.
- W4220740991 hasConceptScore W4220740991C105580179 @default.
- W4220740991 hasConceptScore W4220740991C119394753 @default.
- W4220740991 hasConceptScore W4220740991C149364088 @default.
- W4220740991 hasConceptScore W4220740991C150903083 @default.
- W4220740991 hasConceptScore W4220740991C171250308 @default.
- W4220740991 hasConceptScore W4220740991C178790620 @default.