Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220746876> ?p ?o ?g. }
- W4220746876 endingPage "1316" @default.
- W4220746876 startingPage "1307" @default.
- W4220746876 abstract "Abstract The role of the graft-to-recipient weight ratio (GRWR) in adult liver transplantation (LT) has been poorly investigated so far. The aim is to evaluate the contribution of the GRWR to the well-recognized early allograft dysfunction (EAD) model (i.e., Olthoff model) for the prediction of 90-day graft loss after LT in adults. Three hundred thirty-one consecutive adult patients undergoing LT between 2009 and 2018 at Tor Vergata and Sapienza University in Rome, Italy, served as the Training-Set. The Validation-Set included 123 LTs performed at the Erasmus Medical Center, Rotterdam, the Netherlands. The mEAD model for 90-day graft loss included the following variables: GRWR $$le $$ <mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML> <mml:mo>≤</mml:mo> </mml:math> 1.57 = 2.5, GRWR $$ge $$ <mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML> <mml:mo>≥</mml:mo> </mml:math> 2.13 = 2.5, total bilirubin ≥ 10.0 mg/dL = 2.0, INR ≥ 1.60 = 2.3, and aminotransferase > 2000 IU/L = 2.2. The mEAD model showed an AUC = 0.74 (95%CI = 0.66–0.82; p < 0.001) and AUC = 0.68 (95%CI = 0.58–0.88; p = 0.01) in the Training-Set and Validation-Set, respectively, outperforming conventional EAD in both cohorts (Training-Set: AUC = 0.64, 95%CI = 0.57–0.72; p = 0.001; Validation-Set: AUC = 0.52, 95%CI = 0.35–0.69, p = 0.87). Incorporation of graft weight in a composite multivariate model allowed for better prediction of patients who presented an aminotransferase peak > 2000 IU/L after LT (OR = 2.39, 95%CI = 1.47–3.93, p = 0.0005). The GRWR is important in determining early graft loss after adult LT, and the mEAD model is a useful predictive tool in this perspective, which may assist in improving the graft allocation process." @default.
- W4220746876 created "2022-04-03" @default.
- W4220746876 creator A5012591564 @default.
- W4220746876 creator A5028478773 @default.
- W4220746876 creator A5045633187 @default.
- W4220746876 creator A5050013350 @default.
- W4220746876 creator A5051707461 @default.
- W4220746876 creator A5053205095 @default.
- W4220746876 creator A5053326233 @default.
- W4220746876 creator A5073104114 @default.
- W4220746876 creator A5089127523 @default.
- W4220746876 creator A5090734452 @default.
- W4220746876 date "2022-03-19" @default.
- W4220746876 modified "2023-10-02" @default.
- W4220746876 title "Graft weight integration in the early allograft dysfunction formula improves the prediction of early graft loss after liver transplantation" @default.
- W4220746876 cites W1592290913 @default.
- W4220746876 cites W1677967067 @default.
- W4220746876 cites W1886458881 @default.
- W4220746876 cites W1971441603 @default.
- W4220746876 cites W1973985885 @default.
- W4220746876 cites W1979066818 @default.
- W4220746876 cites W1985306106 @default.
- W4220746876 cites W1987458636 @default.
- W4220746876 cites W1997409606 @default.
- W4220746876 cites W2000568847 @default.
- W4220746876 cites W2017332381 @default.
- W4220746876 cites W2017557941 @default.
- W4220746876 cites W2031915073 @default.
- W4220746876 cites W2038687250 @default.
- W4220746876 cites W2061388593 @default.
- W4220746876 cites W2068866544 @default.
- W4220746876 cites W2074847887 @default.
- W4220746876 cites W2077650783 @default.
- W4220746876 cites W2132504508 @default.
- W4220746876 cites W2167937719 @default.
- W4220746876 cites W2282179082 @default.
- W4220746876 cites W2328176404 @default.
- W4220746876 cites W2330261575 @default.
- W4220746876 cites W2559517375 @default.
- W4220746876 cites W2589460853 @default.
- W4220746876 cites W2738875400 @default.
- W4220746876 cites W2797665619 @default.
- W4220746876 cites W2884346103 @default.
- W4220746876 cites W2911330337 @default.
- W4220746876 cites W3088696153 @default.
- W4220746876 cites W3095615729 @default.
- W4220746876 cites W3127728035 @default.
- W4220746876 cites W3129886283 @default.
- W4220746876 doi "https://doi.org/10.1007/s13304-022-01270-0" @default.
- W4220746876 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35306614" @default.
- W4220746876 hasPublicationYear "2022" @default.
- W4220746876 type Work @default.
- W4220746876 citedByCount "1" @default.
- W4220746876 countsByYear W42207468762023 @default.
- W4220746876 crossrefType "journal-article" @default.
- W4220746876 hasAuthorship W4220746876A5012591564 @default.
- W4220746876 hasAuthorship W4220746876A5028478773 @default.
- W4220746876 hasAuthorship W4220746876A5045633187 @default.
- W4220746876 hasAuthorship W4220746876A5050013350 @default.
- W4220746876 hasAuthorship W4220746876A5051707461 @default.
- W4220746876 hasAuthorship W4220746876A5053205095 @default.
- W4220746876 hasAuthorship W4220746876A5053326233 @default.
- W4220746876 hasAuthorship W4220746876A5073104114 @default.
- W4220746876 hasAuthorship W4220746876A5089127523 @default.
- W4220746876 hasAuthorship W4220746876A5090734452 @default.
- W4220746876 hasBestOaLocation W42207468761 @default.
- W4220746876 hasConcept C11413529 @default.
- W4220746876 hasConcept C126322002 @default.
- W4220746876 hasConcept C126894567 @default.
- W4220746876 hasConcept C141071460 @default.
- W4220746876 hasConcept C142362112 @default.
- W4220746876 hasConcept C2779157386 @default.
- W4220746876 hasConcept C2779609443 @default.
- W4220746876 hasConcept C2911091166 @default.
- W4220746876 hasConcept C33923547 @default.
- W4220746876 hasConcept C52069626 @default.
- W4220746876 hasConcept C52119013 @default.
- W4220746876 hasConcept C71924100 @default.
- W4220746876 hasConceptScore W4220746876C11413529 @default.
- W4220746876 hasConceptScore W4220746876C126322002 @default.
- W4220746876 hasConceptScore W4220746876C126894567 @default.
- W4220746876 hasConceptScore W4220746876C141071460 @default.
- W4220746876 hasConceptScore W4220746876C142362112 @default.
- W4220746876 hasConceptScore W4220746876C2779157386 @default.
- W4220746876 hasConceptScore W4220746876C2779609443 @default.
- W4220746876 hasConceptScore W4220746876C2911091166 @default.
- W4220746876 hasConceptScore W4220746876C33923547 @default.
- W4220746876 hasConceptScore W4220746876C52069626 @default.
- W4220746876 hasConceptScore W4220746876C52119013 @default.
- W4220746876 hasConceptScore W4220746876C71924100 @default.
- W4220746876 hasIssue "4" @default.
- W4220746876 hasLocation W42207468761 @default.
- W4220746876 hasLocation W42207468762 @default.
- W4220746876 hasLocation W42207468763 @default.
- W4220746876 hasLocation W42207468764 @default.
- W4220746876 hasLocation W42207468765 @default.
- W4220746876 hasOpenAccess W4220746876 @default.
- W4220746876 hasPrimaryLocation W42207468761 @default.