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- W4220755845 abstract "We present a comprehensive study of a water-soluble substance from the class of triazine derivatives alkylating agents. The performed physicochemical investigations of this cytostatic drug’s aqueous solutions include the measurements of density, viscosity, speed of sound, refraction index, stability, solubility, distribution between water and octan-1-ol, as well as electronic structure calculations and molecular dynamics modelling. Biologically, the substance was investigated for its cytotoxicity as well as in vitro (on Capan-2 and SK-MEL-1 cell lines) and in vivo (transplantable Ehrlich ascites carcinoma model) therapeutic activity." @default.
- W4220755845 created "2022-04-03" @default.
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- W4220755845 date "2022-06-01" @default.
- W4220755845 modified "2023-10-17" @default.
- W4220755845 title "A cytostatic drug from the class of triazine derivatives: Its properties in aqueous solutions, cytotoxicity, and therapeutic activity" @default.
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- W4220755845 doi "https://doi.org/10.1016/j.molliq.2022.119043" @default.
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