Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220764156> ?p ?o ?g. }
- W4220764156 endingPage "109158182110664" @default.
- W4220764156 startingPage "109158182110664" @default.
- W4220764156 abstract "From a micro to macro scale of biological organization, macromolecular diversity and biological heterogeneity are fundamental properties of biological systems. Heterogeneity may result from genetic, epigenetic, and non-genetic characteristics (e.g., tissue microenvironment). Macromolecular diversity and biological heterogeneity are tolerated as long as the sustenance and propagation of life are not disrupted. They also provide the raw materials for microevolutionary changes that may help organisms adapt to new selection pressures arising from the environment. Sequence evolution, functional divergence, and positive selection of gene and promoter dosage play a major role in the evolution of life's diversity including complex metabolic networks, which is ultimately reflected in changes in the allele frequency over time. Robustness in evolvable biological systems is conferred by functional redundancy that is often created by macromolecular diversity and biological heterogeneity. The ability to investigate biological macromolecules at an increasingly finer level has uncovered a wealth of information in this regard. Therefore, the dynamics of biological complexity should be taken into consideration in biomedical research." @default.
- W4220764156 created "2022-04-03" @default.
- W4220764156 creator A5002807665 @default.
- W4220764156 date "2022-03-21" @default.
- W4220764156 modified "2023-09-25" @default.
- W4220764156 title "Toxicological Implications of Biological Heterogeneity" @default.
- W4220764156 cites W1493474080 @default.
- W4220764156 cites W1507609158 @default.
- W4220764156 cites W1546341583 @default.
- W4220764156 cites W1577729601 @default.
- W4220764156 cites W1638450793 @default.
- W4220764156 cites W1766115599 @default.
- W4220764156 cites W1927239524 @default.
- W4220764156 cites W1982251587 @default.
- W4220764156 cites W1993305178 @default.
- W4220764156 cites W2003274125 @default.
- W4220764156 cites W2008825099 @default.
- W4220764156 cites W2014901209 @default.
- W4220764156 cites W2015709643 @default.
- W4220764156 cites W2027816595 @default.
- W4220764156 cites W2038720497 @default.
- W4220764156 cites W2040628852 @default.
- W4220764156 cites W2052331647 @default.
- W4220764156 cites W2052733258 @default.
- W4220764156 cites W2058864686 @default.
- W4220764156 cites W2064743109 @default.
- W4220764156 cites W2065743337 @default.
- W4220764156 cites W2066511429 @default.
- W4220764156 cites W2085936836 @default.
- W4220764156 cites W2089819802 @default.
- W4220764156 cites W2094148055 @default.
- W4220764156 cites W2098265683 @default.
- W4220764156 cites W2099279699 @default.
- W4220764156 cites W2104549677 @default.
- W4220764156 cites W2105990431 @default.
- W4220764156 cites W2124397449 @default.
- W4220764156 cites W2144172546 @default.
- W4220764156 cites W2144690533 @default.
- W4220764156 cites W2158955275 @default.
- W4220764156 cites W2161910692 @default.
- W4220764156 cites W2162926738 @default.
- W4220764156 cites W2187996097 @default.
- W4220764156 cites W2316224242 @default.
- W4220764156 cites W2499905653 @default.
- W4220764156 cites W2592482187 @default.
- W4220764156 cites W2616652505 @default.
- W4220764156 cites W2765515403 @default.
- W4220764156 cites W2784049056 @default.
- W4220764156 cites W2799812275 @default.
- W4220764156 cites W2885864932 @default.
- W4220764156 cites W2891740518 @default.
- W4220764156 cites W2898863922 @default.
- W4220764156 cites W2913617193 @default.
- W4220764156 cites W2921437380 @default.
- W4220764156 cites W2923030606 @default.
- W4220764156 cites W2955065634 @default.
- W4220764156 cites W2966445275 @default.
- W4220764156 cites W2966506307 @default.
- W4220764156 cites W2977328755 @default.
- W4220764156 cites W3012107004 @default.
- W4220764156 cites W3025360502 @default.
- W4220764156 cites W3046490424 @default.
- W4220764156 cites W3082513061 @default.
- W4220764156 cites W3083874241 @default.
- W4220764156 cites W3083880952 @default.
- W4220764156 cites W3094851849 @default.
- W4220764156 cites W3131612759 @default.
- W4220764156 cites W3200404764 @default.
- W4220764156 cites W4238746614 @default.
- W4220764156 doi "https://doi.org/10.1177/10915818211066492" @default.
- W4220764156 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35311363" @default.
- W4220764156 hasPublicationYear "2022" @default.
- W4220764156 type Work @default.
- W4220764156 citedByCount "1" @default.
- W4220764156 countsByYear W42207641562023 @default.
- W4220764156 crossrefType "journal-article" @default.
- W4220764156 hasAuthorship W4220764156A5002807665 @default.
- W4220764156 hasConcept C104317684 @default.
- W4220764156 hasConcept C154945302 @default.
- W4220764156 hasConcept C18903297 @default.
- W4220764156 hasConcept C201797286 @default.
- W4220764156 hasConcept C2776351498 @default.
- W4220764156 hasConcept C28225019 @default.
- W4220764156 hasConcept C41008148 @default.
- W4220764156 hasConcept C41091548 @default.
- W4220764156 hasConcept C54355233 @default.
- W4220764156 hasConcept C70721500 @default.
- W4220764156 hasConcept C78458016 @default.
- W4220764156 hasConcept C81917197 @default.
- W4220764156 hasConcept C86803240 @default.
- W4220764156 hasConceptScore W4220764156C104317684 @default.
- W4220764156 hasConceptScore W4220764156C154945302 @default.
- W4220764156 hasConceptScore W4220764156C18903297 @default.
- W4220764156 hasConceptScore W4220764156C201797286 @default.
- W4220764156 hasConceptScore W4220764156C2776351498 @default.
- W4220764156 hasConceptScore W4220764156C28225019 @default.
- W4220764156 hasConceptScore W4220764156C41008148 @default.
- W4220764156 hasConceptScore W4220764156C41091548 @default.