Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220785436> ?p ?o ?g. }
- W4220785436 abstract "Healthy mammary gland is essential for milk performance in dairy cows. MicroRNAs (miRNAs) are the key molecules to regulate the steady state of mammary gland in dairy cows. This study investigated the potential role of miR-29c in bovine mammary epithelial cells (bMECs). RNA sequencing (RNA-seq) was used to measure the transcriptome profile of bovine mammary epithelial cells line (MAC-T) transfected with miR-29c inhibitor or negative control (NC) inhibitor, and then differentially expressed genes (DEGs) were screened. The results showed that a total of 42 up-regulated and 27 down-regulated genes were found in the miR-29c inhibitor group compared with the NC inhibitor group. The functional enrichment of the above DEGs indicates that miR-29c is a potential regulator of oxidative stress and inflammatory response in bMECs through multiple genes, such as forkhead box O1 (FOXO1), tumor necrosis factor-alpha (TNF-α), and major histocompatibility complex, class II, DQ alpha 5 (BoLA-DQA5) in the various biological process and signaling pathways of stress-activated mitogen-activated protein kinase (MAPK) cascade, Epstein-Barr virus infection, inflammatory bowel disease, etc. The results imply that miR-29c plays an important role in a steady state of bMECs or cow mammary gland and may be a potential therapeutic target for mastitis in dairy cows." @default.
- W4220785436 created "2022-04-03" @default.
- W4220785436 creator A5014217664 @default.
- W4220785436 creator A5016869122 @default.
- W4220785436 creator A5022217372 @default.
- W4220785436 creator A5035927942 @default.
- W4220785436 creator A5040421931 @default.
- W4220785436 creator A5059439989 @default.
- W4220785436 creator A5068078311 @default.
- W4220785436 creator A5071030373 @default.
- W4220785436 date "2022-04-01" @default.
- W4220785436 modified "2023-09-29" @default.
- W4220785436 title "RNA-Seq Reveals the Role of miR-29c in Regulating Inflammation and Oxidative Stress of Bovine Mammary Epithelial Cells" @default.
- W4220785436 cites W144423133 @default.
- W4220785436 cites W1581610755 @default.
- W4220785436 cites W1820314031 @default.
- W4220785436 cites W1986846519 @default.
- W4220785436 cites W1994758859 @default.
- W4220785436 cites W2004223637 @default.
- W4220785436 cites W2006222057 @default.
- W4220785436 cites W2007542164 @default.
- W4220785436 cites W2036606290 @default.
- W4220785436 cites W2037709602 @default.
- W4220785436 cites W2066113694 @default.
- W4220785436 cites W2092306740 @default.
- W4220785436 cites W2107277218 @default.
- W4220785436 cites W2112189902 @default.
- W4220785436 cites W2126272008 @default.
- W4220785436 cites W2148842621 @default.
- W4220785436 cites W2192080449 @default.
- W4220785436 cites W2219997780 @default.
- W4220785436 cites W2228658966 @default.
- W4220785436 cites W2310203404 @default.
- W4220785436 cites W2513514384 @default.
- W4220785436 cites W2519576150 @default.
- W4220785436 cites W2528491208 @default.
- W4220785436 cites W2728879575 @default.
- W4220785436 cites W2747385354 @default.
- W4220785436 cites W2770988274 @default.
- W4220785436 cites W2793749663 @default.
- W4220785436 cites W2805388105 @default.
- W4220785436 cites W282221905 @default.
- W4220785436 cites W2892177494 @default.
- W4220785436 cites W2896973773 @default.
- W4220785436 cites W2904122309 @default.
- W4220785436 cites W2904870072 @default.
- W4220785436 cites W2910817363 @default.
- W4220785436 cites W2914199723 @default.
- W4220785436 cites W2936167340 @default.
- W4220785436 cites W2945341852 @default.
- W4220785436 cites W2951989942 @default.
- W4220785436 cites W2967550657 @default.
- W4220785436 cites W2973132614 @default.
- W4220785436 cites W2986368462 @default.
- W4220785436 cites W2989061032 @default.
- W4220785436 cites W2989832464 @default.
- W4220785436 cites W2995638049 @default.
- W4220785436 cites W3012129826 @default.
- W4220785436 cites W3013726226 @default.
- W4220785436 cites W3024950597 @default.
- W4220785436 cites W3039811471 @default.
- W4220785436 cites W3046706941 @default.
- W4220785436 cites W3080963650 @default.
- W4220785436 cites W3085236927 @default.
- W4220785436 cites W3090190633 @default.
- W4220785436 cites W3108257732 @default.
- W4220785436 cites W3158319581 @default.
- W4220785436 cites W3161055501 @default.
- W4220785436 cites W3164040204 @default.
- W4220785436 cites W3175752499 @default.
- W4220785436 cites W3176013631 @default.
- W4220785436 cites W3183004073 @default.
- W4220785436 cites W3192166322 @default.
- W4220785436 cites W3207511777 @default.
- W4220785436 cites W3209647649 @default.
- W4220785436 cites W4200262887 @default.
- W4220785436 doi "https://doi.org/10.3389/fvets.2022.865415" @default.
- W4220785436 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35433915" @default.
- W4220785436 hasPublicationYear "2022" @default.
- W4220785436 type Work @default.
- W4220785436 citedByCount "3" @default.
- W4220785436 countsByYear W42207854362022 @default.
- W4220785436 crossrefType "journal-article" @default.
- W4220785436 hasAuthorship W4220785436A5014217664 @default.
- W4220785436 hasAuthorship W4220785436A5016869122 @default.
- W4220785436 hasAuthorship W4220785436A5022217372 @default.
- W4220785436 hasAuthorship W4220785436A5035927942 @default.
- W4220785436 hasAuthorship W4220785436A5040421931 @default.
- W4220785436 hasAuthorship W4220785436A5059439989 @default.
- W4220785436 hasAuthorship W4220785436A5068078311 @default.
- W4220785436 hasAuthorship W4220785436A5071030373 @default.
- W4220785436 hasBestOaLocation W42207854361 @default.
- W4220785436 hasConcept C104317684 @default.
- W4220785436 hasConcept C121608353 @default.
- W4220785436 hasConcept C134018914 @default.
- W4220785436 hasConcept C145059251 @default.
- W4220785436 hasConcept C150194340 @default.
- W4220785436 hasConcept C153911025 @default.
- W4220785436 hasConcept C162317418 @default.
- W4220785436 hasConcept C17991360 @default.