FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220785500> ?p ?o ?g. }

• W4220785500 endingPage "1171" @default.
• W4220785500 startingPage "1155" @default.
• W4220785500 abstract "Intrinsically disordered proteins are frequently involved in important regulatory processes in the cell thanks to their ability to bind several different targets performing sometimes even opposite functions. The PentUnFOLD algorithm is a physicochemical method that is based on new propensity scales for disordered, nonstable and stable elements of secondary structure and on the counting of stabilizing and destabilizing intraprotein contacts. Unlike other methods, it works with a PDB file, and it can determine not only those fragments of alpha helices, beta strands, and random coils that can turn into disordered state (the “dark” side of the disorder), but also nonstable regions of alpha helices and beta strands which are able to turn into random coils (the “light” side), and vice versa (H ↔ C, E ↔ C). The scales have been obtained from structural data on disordered regions from the middle parts of amino acid sequences only, and not on their expectedly disordered N- and C-termini. Among other tendencies we have found that regions of both alpha helices and beta strands that can turn into the disordered state are relatively enriched in residues of Ala, Met, Asp, and Lys, while regions of both alpha helices and beta strands that can turn into random coil are relatively enriched in hydrophilic residues, and Cys, Pro, and Gly. Moreover, PentUnFOLD has the option to determine the effect of secondary structure transitions on the stability of a given region of a protein. The PentUnFOLD algorithm is freely available at http://3.17.12.213/pent-un-fold and http://chemres.bsmu.by/PentUnFOLD.htm ." @default.
• W4220785500 created "2022-04-03" @default.
• W4220785500 creator A5000933985 @default.
• W4220785500 creator A5001020310 @default.
• W4220785500 creator A5035069757 @default.
• W4220785500 creator A5037610499 @default.
• W4220785500 creator A5057599022 @default.
• W4220785500 date "2022-03-16" @default.
• W4220785500 modified "2023-09-27" @default.
• W4220785500 title "The PentUnFOLD algorithm as a tool to distinguish the dark and the light sides of the structural instability of proteins" @default.
• W4220785500 cites W1691219312 @default.
• W4220785500 cites W1763894483 @default.
• W4220785500 cites W1792685479 @default.
• W4220785500 cites W184073726 @default.
• W4220785500 cites W1968682237 @default.
• W4220785500 cites W1989511016 @default.
• W4220785500 cites W2006192061 @default.
• W4220785500 cites W2008708467 @default.
• W4220785500 cites W2014776147 @default.
• W4220785500 cites W2016170088 @default.
• W4220785500 cites W2023487073 @default.
• W4220785500 cites W2025816743 @default.
• W4220785500 cites W2030776726 @default.
• W4220785500 cites W2037076861 @default.
• W4220785500 cites W2049476357 @default.
• W4220785500 cites W2049934777 @default.
• W4220785500 cites W2051119339 @default.
• W4220785500 cites W2052894646 @default.
• W4220785500 cites W2053820259 @default.
• W4220785500 cites W2055193239 @default.
• W4220785500 cites W2055630932 @default.
• W4220785500 cites W2058279732 @default.
• W4220785500 cites W2060592742 @default.
• W4220785500 cites W2069479748 @default.
• W4220785500 cites W2073792698 @default.
• W4220785500 cites W2086189298 @default.
• W4220785500 cites W2090630809 @default.
• W4220785500 cites W2097891553 @default.
• W4220785500 cites W2102818658 @default.
• W4220785500 cites W2104412724 @default.
• W4220785500 cites W2110869427 @default.
• W4220785500 cites W2114823344 @default.
• W4220785500 cites W2118608964 @default.
• W4220785500 cites W2120767856 @default.
• W4220785500 cites W2126064524 @default.
• W4220785500 cites W2126719129 @default.
• W4220785500 cites W2131965976 @default.
• W4220785500 cites W2132720084 @default.
• W4220785500 cites W2149653886 @default.
• W4220785500 cites W2156407548 @default.
• W4220785500 cites W2162980545 @default.
• W4220785500 cites W2167061681 @default.
• W4220785500 cites W2168970921 @default.
• W4220785500 cites W2170563234 @default.
• W4220785500 cites W2292990827 @default.
• W4220785500 cites W2463988437 @default.
• W4220785500 cites W2535071049 @default.
• W4220785500 cites W2547198137 @default.
• W4220785500 cites W2571643507 @default.
• W4220785500 cites W2604186692 @default.
• W4220785500 cites W2912753500 @default.
• W4220785500 cites W2950334910 @default.
• W4220785500 cites W2980746976 @default.
• W4220785500 cites W2982547327 @default.
• W4220785500 cites W2996457856 @default.
• W4220785500 cites W3011698511 @default.
• W4220785500 cites W3042910057 @default.
• W4220785500 cites W3156051371 @default.
• W4220785500 cites W3184265853 @default.
• W4220785500 cites W4234635809 @default.
• W4220785500 cites W4240929891 @default.
• W4220785500 doi "https://doi.org/10.1007/s00726-022-03153-5" @default.
• W4220785500 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35294674" @default.
• W4220785500 hasPublicationYear "2022" @default.
• W4220785500 type Work @default.
• W4220785500 citedByCount "2" @default.
• W4220785500 countsByYear W42207855002022 @default.
• W4220785500 countsByYear W42207855002023 @default.
• W4220785500 crossrefType "journal-article" @default.
• W4220785500 hasAuthorship W4220785500A5000933985 @default.
• W4220785500 hasAuthorship W4220785500A5001020310 @default.
• W4220785500 hasAuthorship W4220785500A5035069757 @default.
• W4220785500 hasAuthorship W4220785500A5037610499 @default.
• W4220785500 hasAuthorship W4220785500A5057599022 @default.
• W4220785500 hasBestOaLocation W42207855001 @default.
• W4220785500 hasConcept C11413529 @default.
• W4220785500 hasConcept C119145174 @default.
• W4220785500 hasConcept C121332964 @default.
• W4220785500 hasConcept C184538305 @default.
• W4220785500 hasConcept C185592680 @default.
• W4220785500 hasConcept C2778815515 @default.
• W4220785500 hasConcept C2988375501 @default.
• W4220785500 hasConcept C34349673 @default.
• W4220785500 hasConcept C41008148 @default.
• W4220785500 hasConcept C46141821 @default.
• W4220785500 hasConcept C47701112 @default.
• W4220785500 hasConcept C55493867 @default.
• W4220785500 hasConcept C62614982 @default.

• next