Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220785506> ?p ?o ?g. }
- W4220785506 abstract "Prokaryotic genomes are replete with mobile genetic elements (MGE) that span a continuum of replication autonomy. On numerous occasions during microbial evolution, diverse MGE lose their autonomy altogether but, rather than being quickly purged from the host genome, assume a new function that benefits the host, rendering the immobilized MGE subject to purifying selection, and resulting in its vertical inheritance. This mini-review highlights the diversity of the repurposed (exapted) MGE as well as the plethora of cellular functions that they perform. The principal contribution of the exaptation of MGE and their components is to the prokaryotic functional systems involved in biological conflicts, and in particular, defense against viruses and other MGE. This evolutionary entanglement between MGE and defense systems appears to stem both from mechanistic similarities and from similar evolutionary predicaments whereby both MGEs and defense systems tend to incur fitness costs to the hosts and thereby evolve mechanisms for survival including horizontal mobility, causing host addiction, and exaptation for functions beneficial to the host. The examples discussed demonstrate that the identity of an MGE, overall mobility and relationship with the host cell (mutualistic, symbiotic, commensal, or parasitic) are all factors that affect exaptation." @default.
- W4220785506 created "2022-04-03" @default.
- W4220785506 creator A5035240489 @default.
- W4220785506 creator A5064925165 @default.
- W4220785506 date "2022-03-24" @default.
- W4220785506 modified "2023-10-04" @default.
- W4220785506 title "Recruitment of Mobile Genetic Elements for Diverse Cellular Functions in Prokaryotes" @default.
- W4220785506 cites W1514080071 @default.
- W4220785506 cites W1532814292 @default.
- W4220785506 cites W1583860065 @default.
- W4220785506 cites W1585879834 @default.
- W4220785506 cites W1744825685 @default.
- W4220785506 cites W1756965619 @default.
- W4220785506 cites W1778805103 @default.
- W4220785506 cites W1860449000 @default.
- W4220785506 cites W1860484030 @default.
- W4220785506 cites W1902154476 @default.
- W4220785506 cites W1916363404 @default.
- W4220785506 cites W1921607560 @default.
- W4220785506 cites W1945645700 @default.
- W4220785506 cites W1967886452 @default.
- W4220785506 cites W1971912164 @default.
- W4220785506 cites W1975679166 @default.
- W4220785506 cites W1976555793 @default.
- W4220785506 cites W1977640433 @default.
- W4220785506 cites W1979069244 @default.
- W4220785506 cites W1984626450 @default.
- W4220785506 cites W1988370253 @default.
- W4220785506 cites W1991358243 @default.
- W4220785506 cites W1994028292 @default.
- W4220785506 cites W1994782280 @default.
- W4220785506 cites W1996035684 @default.
- W4220785506 cites W1996131911 @default.
- W4220785506 cites W1996463917 @default.
- W4220785506 cites W1998231027 @default.
- W4220785506 cites W2003660859 @default.
- W4220785506 cites W2003875234 @default.
- W4220785506 cites W2011700794 @default.
- W4220785506 cites W2012866652 @default.
- W4220785506 cites W2013829822 @default.
- W4220785506 cites W2019653420 @default.
- W4220785506 cites W2023505705 @default.
- W4220785506 cites W2025447131 @default.
- W4220785506 cites W2026277222 @default.
- W4220785506 cites W2027831845 @default.
- W4220785506 cites W2030745567 @default.
- W4220785506 cites W2032293502 @default.
- W4220785506 cites W2040074940 @default.
- W4220785506 cites W2040836575 @default.
- W4220785506 cites W2044022101 @default.
- W4220785506 cites W2044915317 @default.
- W4220785506 cites W2047794361 @default.
- W4220785506 cites W2050078498 @default.
- W4220785506 cites W2052781554 @default.
- W4220785506 cites W2054268736 @default.
- W4220785506 cites W2054811359 @default.
- W4220785506 cites W2055252390 @default.
- W4220785506 cites W2056025495 @default.
- W4220785506 cites W2056443861 @default.
- W4220785506 cites W2056649927 @default.
- W4220785506 cites W2057754366 @default.
- W4220785506 cites W2070036439 @default.
- W4220785506 cites W2071444861 @default.
- W4220785506 cites W2071603133 @default.
- W4220785506 cites W2072353637 @default.
- W4220785506 cites W2072812437 @default.
- W4220785506 cites W2075827435 @default.
- W4220785506 cites W2080380632 @default.
- W4220785506 cites W2084845069 @default.
- W4220785506 cites W2087089981 @default.
- W4220785506 cites W2089947330 @default.
- W4220785506 cites W2090659087 @default.
- W4220785506 cites W2094308587 @default.
- W4220785506 cites W2095624846 @default.
- W4220785506 cites W2095970339 @default.
- W4220785506 cites W2098558111 @default.
- W4220785506 cites W2098891503 @default.
- W4220785506 cites W2099545371 @default.
- W4220785506 cites W2102964870 @default.
- W4220785506 cites W2105585246 @default.
- W4220785506 cites W2106533942 @default.
- W4220785506 cites W2107109782 @default.
- W4220785506 cites W2107986672 @default.
- W4220785506 cites W2110399041 @default.
- W4220785506 cites W2114637595 @default.
- W4220785506 cites W2115575411 @default.
- W4220785506 cites W2121166240 @default.
- W4220785506 cites W2124215787 @default.
- W4220785506 cites W2126806448 @default.
- W4220785506 cites W2127096778 @default.
- W4220785506 cites W2127288348 @default.
- W4220785506 cites W2138811562 @default.
- W4220785506 cites W2139095560 @default.
- W4220785506 cites W2139958262 @default.
- W4220785506 cites W2145522206 @default.
- W4220785506 cites W2150296575 @default.
- W4220785506 cites W2150808625 @default.
- W4220785506 cites W2155993242 @default.
- W4220785506 cites W2160347838 @default.
- W4220785506 cites W2160521062 @default.