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- W4220786372 abstract "Non-alcoholic fatty liver disease (NAFLD) remains a common disease with a significant health and economic burden worldwide. The gut microbiota (GM) and bile acids (BAs), which play important roles in the gut-liver axis, have been confirmed to jointly participate in the development of NAFLD. GM not only regulate bile acids' synthesis, transport, and reabsorption by regulating other metabolites (such as trimetlyl amine oxide, butyrate), but also regulate dehydrogenation, dehydroxylation and desulfurization of bile acids. Meanwhile, disordered bile acids influence the gut microbiota mainly through promoting the bacterial death and lowering the microbial diversity. Although weight loss and lifestyle changes are effective in the treatment of NAFLD, the acceptability and compliance of patients are poor. Recently, increasing natural plants and their active ingredients have been proved to alleviate NAFLD by modulating the joint action of gut microbiota and bile acids, and considered to be promising potential candidates. In this review, we discuss the efficacy of natural plants in treating NAFLD in the context of their regulation of the complex interplay between the gut microbiota and bile acids, the crosstalk of which has been shown to significantly promote the progression of NAFLD. Herein, we summarize the prior work on this topic and further suggest future research directions in the field." @default.
- W4220786372 created "2022-04-03" @default.
- W4220786372 creator A5001173965 @default.
- W4220786372 creator A5021695326 @default.
- W4220786372 creator A5043234647 @default.
- W4220786372 creator A5046937939 @default.
- W4220786372 creator A5047124158 @default.
- W4220786372 date "2022-03-09" @default.
- W4220786372 modified "2023-10-18" @default.
- W4220786372 title "Therapeutic Potential of Natural Plants Against Non-Alcoholic Fatty Liver Disease: Targeting the Interplay Between Gut Microbiota and Bile Acids" @default.
- W4220786372 cites W1656419014 @default.
- W4220786372 cites W1974616640 @default.
- W4220786372 cites W2011009707 @default.
- W4220786372 cites W2035336470 @default.
- W4220786372 cites W2056385643 @default.
- W4220786372 cites W2071273298 @default.
- W4220786372 cites W2073332363 @default.
- W4220786372 cites W2078034893 @default.
- W4220786372 cites W2079166934 @default.
- W4220786372 cites W2079588482 @default.
- W4220786372 cites W2091106363 @default.
- W4220786372 cites W2119331100 @default.
- W4220786372 cites W2123561714 @default.
- W4220786372 cites W2134897177 @default.
- W4220786372 cites W2144178804 @default.
- W4220786372 cites W2147259528 @default.
- W4220786372 cites W2150345900 @default.
- W4220786372 cites W2169330513 @default.
- W4220786372 cites W2180141563 @default.
- W4220786372 cites W2409571319 @default.
- W4220786372 cites W2418984266 @default.
- W4220786372 cites W2430468952 @default.
- W4220786372 cites W2468692184 @default.
- W4220786372 cites W2500423279 @default.
- W4220786372 cites W2519008943 @default.
- W4220786372 cites W2530047389 @default.
- W4220786372 cites W2554714705 @default.
- W4220786372 cites W2588130051 @default.
- W4220786372 cites W2598671553 @default.
- W4220786372 cites W2605955022 @default.
- W4220786372 cites W2616178818 @default.
- W4220786372 cites W2733879401 @default.
- W4220786372 cites W2737365800 @default.
- W4220786372 cites W2752959950 @default.
- W4220786372 cites W2754032461 @default.
- W4220786372 cites W2758092834 @default.
- W4220786372 cites W2761145411 @default.
- W4220786372 cites W2762689525 @default.
- W4220786372 cites W2792178736 @default.
- W4220786372 cites W2797884982 @default.
- W4220786372 cites W2810423511 @default.
- W4220786372 cites W2888639734 @default.
- W4220786372 cites W2894120184 @default.
- W4220786372 cites W2895385168 @default.
- W4220786372 cites W2897500043 @default.
- W4220786372 cites W2899720772 @default.
- W4220786372 cites W2904286439 @default.
- W4220786372 cites W2907493655 @default.
- W4220786372 cites W2910086017 @default.
- W4220786372 cites W2910151637 @default.
- W4220786372 cites W2912022821 @default.
- W4220786372 cites W2912816189 @default.
- W4220786372 cites W2926774250 @default.
- W4220786372 cites W2944625943 @default.
- W4220786372 cites W2946264652 @default.
- W4220786372 cites W2952656298 @default.
- W4220786372 cites W2955075898 @default.
- W4220786372 cites W2971631459 @default.
- W4220786372 cites W2978907259 @default.
- W4220786372 cites W2979675761 @default.
- W4220786372 cites W2982127187 @default.
- W4220786372 cites W2982531730 @default.
- W4220786372 cites W2989301567 @default.
- W4220786372 cites W2996083034 @default.
- W4220786372 cites W2996185021 @default.
- W4220786372 cites W2998921778 @default.
- W4220786372 cites W3002784583 @default.
- W4220786372 cites W3004812588 @default.
- W4220786372 cites W3007020911 @default.
- W4220786372 cites W3008199108 @default.
- W4220786372 cites W3009231580 @default.
- W4220786372 cites W3009620456 @default.
- W4220786372 cites W3014133656 @default.
- W4220786372 cites W3033244660 @default.
- W4220786372 cites W3037735066 @default.
- W4220786372 cites W3084282448 @default.
- W4220786372 cites W3087011675 @default.
- W4220786372 cites W3090680729 @default.
- W4220786372 cites W3107083588 @default.
- W4220786372 cites W3115308183 @default.
- W4220786372 cites W3116303244 @default.
- W4220786372 cites W3119476067 @default.
- W4220786372 cites W3124894549 @default.
- W4220786372 cites W3154897461 @default.
- W4220786372 cites W3176216378 @default.
- W4220786372 cites W3198648630 @default.
- W4220786372 cites W3200322695 @default.
- W4220786372 cites W3217525028 @default.
- W4220786372 doi "https://doi.org/10.3389/fcimb.2022.854879" @default.
- W4220786372 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35356532" @default.