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- W4220789615 abstract "Vasculogenesis is the de novo formation of vessels that establishes the vasculature. It specifically refers the production of new blood and lymphatic vessels via the recruitment of bone-marrow-derived progenitor cells that have an endothelial differentiation capacity (i.e., endothelial progenitor cells; EPCs). This chapter focuses on the roles of bone-marrow-derived EPCs in postnatal vasculogenesis and addresses the phenotypical identification of EPCs and their signaling pathways. It provides a brief introduction to the key signaling molecules that are essential for endothelial cell function and vasculogenesis. In the veterinary field, lessons learned from the differentiation of EPCs in vitro may be extended to studies on domestic and other species, providing a novel and better strategy to research vascular disorders, such as malignant vascular tumors (e.g., hemangiosarcoma) and cardiovascular diseases. Furthermore, the development of specific reagents for animal species and experimental applications could lead to a sophisticated assessment of the functions of EPCs." @default.
- W4220789615 created "2022-04-03" @default.
- W4220789615 creator A5050160834 @default.
- W4220789615 date "2022-03-04" @default.
- W4220789615 modified "2023-09-27" @default.
- W4220789615 title "Vasculogenesis and Endothelial Cell Production" @default.
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- W4220789615 doi "https://doi.org/10.1002/9781119500537.ch5" @default.
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