FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220792453> ?p ?o ?g. }

• W4220792453 endingPage "100250" @default.
• W4220792453 startingPage "100250" @default.
• W4220792453 abstract "We have previously shown that schizophrenia (SCZ) participants with high community functioning demonstrate better verbal working memory (vWM) performance relative to those with low community functioning. In the present study, we investigated whether neuroanatomical differences in regions supporting vWM also exist between schizophrenia groups that vary on community functioning. Utilizing magnetic resonance imaging, shape features of deep-brain nuclei known to be involved in vWM were calculated in samples of high functioning (HF-SCZ, n = 23) and low functioning schizophrenia participants (LF-SCZ, n = 18), as well as in a group of healthy control participants (CON, n = 45). Large deformation diffeomorphic metric mapping was employed to characterize surface anatomy of the caudate nucleus, globus pallidus, hippocampus, and thalamus. Statistical analyses involved linear mixed-effects models and vertex-wise contrast mapping to assess between-group differences in structural shape features, and Pearson correlations to evaluate relationships between shape metrics and vWM performance. We found significant between-group main effects in deep-brain surface anatomy across all structures. Post-hoc comparisons revealed HF-SCZ and LF-SCZ groups significantly differed on both caudate and hippocampal shape, however, significant correlations with vWM were only observed in hippocampal shape for both SCZ groups. Specifically, more abnormal hippocampal deformation was associated with lower vWM suggesting hippocampal shape is both a neural substrate for vWM deficits and a potential biomarker to predict or monitor the efficacy of cognitive rehabilitation. These findings add to a growing body of literature related to functional outcomes in schizophrenia by demonstrating unique shape patterns across the spectrum of community functioning in SCZ." @default.
• W4220792453 created "2022-04-03" @default.
• W4220792453 creator A5023552016 @default.
• W4220792453 creator A5029205656 @default.
• W4220792453 creator A5032066361 @default.
• W4220792453 creator A5062155936 @default.
• W4220792453 creator A5072481624 @default.
• W4220792453 creator A5073216396 @default.
• W4220792453 date "2022-09-01" @default.
• W4220792453 modified "2023-10-14" @default.
• W4220792453 title "Shape features of working memory-related deep-brain regions differentiate high and low community functioning in schizophrenia" @default.
• W4220792453 cites W1503893179 @default.
• W4220792453 cites W1876943069 @default.
• W4220792453 cites W1957981791 @default.
• W4220792453 cites W1965146525 @default.
• W4220792453 cites W1965924747 @default.
• W4220792453 cites W1981493935 @default.
• W4220792453 cites W1985720446 @default.
• W4220792453 cites W1985802733 @default.
• W4220792453 cites W1991441060 @default.
• W4220792453 cites W2001783963 @default.
• W4220792453 cites W2015779008 @default.
• W4220792453 cites W2026405123 @default.
• W4220792453 cites W2028311481 @default.
• W4220792453 cites W2043564452 @default.
• W4220792453 cites W2045533646 @default.
• W4220792453 cites W2050462207 @default.
• W4220792453 cites W2052459710 @default.
• W4220792453 cites W2085390488 @default.
• W4220792453 cites W2085894775 @default.
• W4220792453 cites W2093625493 @default.
• W4220792453 cites W2094767250 @default.
• W4220792453 cites W2111525009 @default.
• W4220792453 cites W2111763773 @default.
• W4220792453 cites W2112518510 @default.
• W4220792453 cites W2118096594 @default.
• W4220792453 cites W2119503480 @default.
• W4220792453 cites W2122086417 @default.
• W4220792453 cites W2122267892 @default.
• W4220792453 cites W2129558945 @default.
• W4220792453 cites W2134229863 @default.
• W4220792453 cites W2137547644 @default.
• W4220792453 cites W2152391756 @default.
• W4220792453 cites W2156123885 @default.
• W4220792453 cites W2162080735 @default.
• W4220792453 cites W2170883616 @default.
• W4220792453 cites W2276269666 @default.
• W4220792453 cites W2409167388 @default.
• W4220792453 cites W2509424180 @default.
• W4220792453 cites W2528213969 @default.
• W4220792453 cites W2588930864 @default.
• W4220792453 cites W2620708955 @default.
• W4220792453 cites W2898233222 @default.
• W4220792453 cites W2947670548 @default.
• W4220792453 cites W2949236733 @default.
• W4220792453 cites W3042148770 @default.
• W4220792453 cites W3142506171 @default.
• W4220792453 cites W3192591882 @default.
• W4220792453 cites W3195396774 @default.
• W4220792453 cites W3196689162 @default.
• W4220792453 cites W37330363 @default.
• W4220792453 doi "https://doi.org/10.1016/j.scog.2022.100250" @default.
• W4220792453 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35368990" @default.
• W4220792453 hasPublicationYear "2022" @default.
• W4220792453 type Work @default.
• W4220792453 citedByCount "1" @default.
• W4220792453 countsByYear W42207924532023 @default.
• W4220792453 crossrefType "journal-article" @default.
• W4220792453 hasAuthorship W4220792453A5023552016 @default.
• W4220792453 hasAuthorship W4220792453A5029205656 @default.
• W4220792453 hasAuthorship W4220792453A5032066361 @default.
• W4220792453 hasAuthorship W4220792453A5062155936 @default.
• W4220792453 hasAuthorship W4220792453A5072481624 @default.
• W4220792453 hasAuthorship W4220792453A5073216396 @default.
• W4220792453 hasBestOaLocation W42207924531 @default.
• W4220792453 hasConcept C118552586 @default.
• W4220792453 hasConcept C148762608 @default.
• W4220792453 hasConcept C15744967 @default.
• W4220792453 hasConcept C169760540 @default.
• W4220792453 hasConcept C169900460 @default.
• W4220792453 hasConcept C21963081 @default.
• W4220792453 hasConcept C2776412080 @default.
• W4220792453 hasConcept C2778187257 @default.
• W4220792453 hasConcept C2780278869 @default.
• W4220792453 hasConcept C2781423529 @default.
• W4220792453 hasConcept C529278444 @default.
• W4220792453 hasConcept C58693492 @default.
• W4220792453 hasConceptScore W4220792453C118552586 @default.
• W4220792453 hasConceptScore W4220792453C148762608 @default.
• W4220792453 hasConceptScore W4220792453C15744967 @default.
• W4220792453 hasConceptScore W4220792453C169760540 @default.
• W4220792453 hasConceptScore W4220792453C169900460 @default.
• W4220792453 hasConceptScore W4220792453C21963081 @default.
• W4220792453 hasConceptScore W4220792453C2776412080 @default.
• W4220792453 hasConceptScore W4220792453C2778187257 @default.
• W4220792453 hasConceptScore W4220792453C2780278869 @default.
• W4220792453 hasConceptScore W4220792453C2781423529 @default.
• W4220792453 hasConceptScore W4220792453C529278444 @default.

• next