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- W4220793480 abstract "HPV-associated oropharyngeal cancer (OPC) has one of the most rapidly rising incidences of any cancer in high-income countries. HPV vaccination is being tested to prevent HPV-associated OPC.To determine the effect of Human Papilloma Virus (HPV) vaccination on the prevention of OPC in adults worldwide.Scoping review conducted using PRISMA-ScR Checklist.An electronic literature search identified relevant records. Titles and abstracts were screened to assess eligibility by two researchers, and data from relevant full-text articles were extracted and synthesised.Three-hundred-and-forty-three studies were identified, with eleven articles meeting the inclusion criteria. The most common study design was cross-sectional (n = 7), the most common location was the US (n = 6) and data collection periods spanned 2004 to 2020. One article found unvaccinated participants had a 19 times increased risk of developing OPC compared with those who had been vaccinated against HPV. The remaining papers showed that prevalence of HPV-vaccine-type oral infection was significantly lower in vaccinated participants than unvaccinated participants, with a reduction of oral HPV detection ranging from 72% to 93%. This reduction varied by sex.There is evidence to suggest that HPV vaccination reduces oral HPV infection and decreases the incidence of HPV-associated OPC. There is substantial need for further research which directly examines the relationship between HPV vaccination status and subsequent OPC development." @default.
- W4220793480 created "2022-04-03" @default.
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- W4220793480 date "2022-03-01" @default.
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- W4220793480 title "The impact of HPV vaccination on the prevention of oropharyngeal cancer: A scoping review." @default.
- W4220793480 doi "https://doi.org/10.1922/cdh_00072kaczmarczyk08" @default.
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