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- W4220793887 abstract "The arms race between fungal pathogens and plant hosts involves recognition of fungal effectors to induce host immunity. Although various fungal effectors have been identified, the effector functions of ribonucleases are largely unknown. Herein, we identified a ribonuclease secreted by Verticillium dahliae (VdRTX1) that translocates into the plant nucleus to modulate immunity. The activity of VdRTX1 causes hypersensitive response (HR)-related cell death in Nicotiana benthamiana and cotton. VdRTX1 possesses a signal peptide but is unlikely to be an apoplastic effector because its nuclear localization in the plant is necessary for cell death induction. Knockout of VdRTX1 significantly enhanced V. dahliae virulence on tobacco while V. dahliae employs the known suppressor VdCBM1 to escape the immunity induced by VdRTX1. VdRTX1 homologs are widely distributed in fungi but transient expression of 24 homologs from other fungi did not yield cell death induction, suggesting that this function is specific to the VdRTX1 in V. dahliae. Expression of site-directed mutants of VdRTX1 in N. benthamiana leaves revealed conserved ligand-binding sites that are important for VdRTX1 function in inducing cell death. Thus, VdRTX1 functions as a unique HR-inducing effector in V. dahliae that contributes to the activation of plant immunity." @default.
- W4220793887 created "2022-04-03" @default.
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- W4220793887 date "2022-04-01" @default.
- W4220793887 modified "2023-10-13" @default.
- W4220793887 title "A secreted ribonuclease effector from <i>Verticillium dahliae</i> localizes in the plant nucleus to modulate host immunity" @default.
- W4220793887 cites W1493980809 @default.
- W4220793887 cites W1968109024 @default.
- W4220793887 cites W1973731551 @default.
- W4220793887 cites W1984444442 @default.
- W4220793887 cites W1995828353 @default.
- W4220793887 cites W2003847336 @default.
- W4220793887 cites W2010854320 @default.
- W4220793887 cites W2013869770 @default.
- W4220793887 cites W2015230642 @default.
- W4220793887 cites W2015624992 @default.
- W4220793887 cites W2017334980 @default.
- W4220793887 cites W2021962147 @default.
- W4220793887 cites W2024495671 @default.
- W4220793887 cites W2025621453 @default.
- W4220793887 cites W2027177819 @default.
- W4220793887 cites W2035940511 @default.
- W4220793887 cites W2044385778 @default.
- W4220793887 cites W2057742915 @default.
- W4220793887 cites W2090677935 @default.
- W4220793887 cites W2093827798 @default.
- W4220793887 cites W2094201044 @default.
- W4220793887 cites W2094458603 @default.
- W4220793887 cites W2097382368 @default.
- W4220793887 cites W2102370923 @default.
- W4220793887 cites W2102967742 @default.
- W4220793887 cites W2106195372 @default.
- W4220793887 cites W2106395760 @default.
- W4220793887 cites W2107277218 @default.
- W4220793887 cites W2114829816 @default.
- W4220793887 cites W2114835024 @default.
- W4220793887 cites W2123810848 @default.
- W4220793887 cites W2124088653 @default.
- W4220793887 cites W2124544231 @default.
- W4220793887 cites W2126408709 @default.
- W4220793887 cites W2137037625 @default.
- W4220793887 cites W2137871007 @default.
- W4220793887 cites W2149288921 @default.
- W4220793887 cites W2151042817 @default.
- W4220793887 cites W2151089908 @default.
- W4220793887 cites W2151138136 @default.
- W4220793887 cites W2151210926 @default.
- W4220793887 cites W2152207030 @default.
- W4220793887 cites W2152272455 @default.
- W4220793887 cites W2152770371 @default.
- W4220793887 cites W2153323182 @default.
- W4220793887 cites W2155156659 @default.
- W4220793887 cites W2156925921 @default.
- W4220793887 cites W2157978879 @default.
- W4220793887 cites W2158173168 @default.
- W4220793887 cites W2158335357 @default.
- W4220793887 cites W2158581601 @default.
- W4220793887 cites W2160782336 @default.
- W4220793887 cites W2162002946 @default.
- W4220793887 cites W2162515800 @default.
- W4220793887 cites W2167253300 @default.
- W4220793887 cites W2167587014 @default.
- W4220793887 cites W2168869451 @default.
- W4220793887 cites W2170636855 @default.
- W4220793887 cites W2171209136 @default.
- W4220793887 cites W2171756111 @default.
- W4220793887 cites W2192080449 @default.
- W4220793887 cites W2311203695 @default.
- W4220793887 cites W2505457969 @default.
- W4220793887 cites W2522639609 @default.
- W4220793887 cites W2546021351 @default.
- W4220793887 cites W2588379742 @default.
- W4220793887 cites W2591266398 @default.
- W4220793887 cites W2598527232 @default.
- W4220793887 cites W2605647237 @default.
- W4220793887 cites W2765610488 @default.
- W4220793887 cites W2766544879 @default.
- W4220793887 cites W2800674123 @default.
- W4220793887 cites W2907499859 @default.
- W4220793887 cites W2921939310 @default.
- W4220793887 cites W2951870836 @default.
- W4220793887 cites W2952816309 @default.
- W4220793887 cites W2954586707 @default.
- W4220793887 cites W2972016620 @default.
- W4220793887 cites W3011674071 @default.
- W4220793887 cites W3093868212 @default.
- W4220793887 cites W3149671239 @default.