Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220794310> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W4220794310 endingPage "101252" @default.
- W4220794310 startingPage "101252" @default.
- W4220794310 abstract "BAX activation techniques are crucial to studying the intrinsic pathway of apoptosis— thousands of pro-apoptotic signals converge on BAX activation. Current methodologies are predominantly limited to membrane permeabilization studies, which assess endpoint functionality of oligomeric BAX, but overlook early activation steps of cytosolic BAX. Here we detail FLAMBE: a fluorescence polarization ligand assay for monitoring BAX early-activation in solution. We also describe a dual-metric parameterization strategy for distillation of kinetic data and comparative analyses when studying candidate ligands. For complete details on the use and execution of this protocol, please refer to Gelles et al. (2022)." @default.
- W4220794310 created "2022-04-03" @default.
- W4220794310 creator A5016580341 @default.
- W4220794310 creator A5045371325 @default.
- W4220794310 creator A5061440261 @default.
- W4220794310 date "2022-06-01" @default.
- W4220794310 modified "2023-10-18" @default.
- W4220794310 title "FLAMBE: A kinetic fluorescence polarization assay to study activation of monomeric BAX" @default.
- W4220794310 cites W1980099111 @default.
- W4220794310 cites W2002934131 @default.
- W4220794310 cites W2012076962 @default.
- W4220794310 cites W2032049833 @default.
- W4220794310 cites W2142713529 @default.
- W4220794310 cites W2165179086 @default.
- W4220794310 cites W2734442873 @default.
- W4220794310 cites W2913919474 @default.
- W4220794310 cites W4220753809 @default.
- W4220794310 cites W80462140 @default.
- W4220794310 doi "https://doi.org/10.1016/j.xpro.2022.101252" @default.
- W4220794310 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35313708" @default.
- W4220794310 hasPublicationYear "2022" @default.
- W4220794310 type Work @default.
- W4220794310 citedByCount "1" @default.
- W4220794310 countsByYear W42207943102022 @default.
- W4220794310 crossrefType "journal-article" @default.
- W4220794310 hasAuthorship W4220794310A5016580341 @default.
- W4220794310 hasAuthorship W4220794310A5045371325 @default.
- W4220794310 hasAuthorship W4220794310A5061440261 @default.
- W4220794310 hasBestOaLocation W42207943101 @default.
- W4220794310 hasConcept C111357860 @default.
- W4220794310 hasConcept C121332964 @default.
- W4220794310 hasConcept C12554922 @default.
- W4220794310 hasConcept C148898269 @default.
- W4220794310 hasConcept C181199279 @default.
- W4220794310 hasConcept C185592680 @default.
- W4220794310 hasConcept C186060115 @default.
- W4220794310 hasConcept C190283241 @default.
- W4220794310 hasConcept C41625074 @default.
- W4220794310 hasConcept C55493867 @default.
- W4220794310 hasConcept C62520636 @default.
- W4220794310 hasConcept C86803240 @default.
- W4220794310 hasConcept C91881484 @default.
- W4220794310 hasConcept C98539663 @default.
- W4220794310 hasConceptScore W4220794310C111357860 @default.
- W4220794310 hasConceptScore W4220794310C121332964 @default.
- W4220794310 hasConceptScore W4220794310C12554922 @default.
- W4220794310 hasConceptScore W4220794310C148898269 @default.
- W4220794310 hasConceptScore W4220794310C181199279 @default.
- W4220794310 hasConceptScore W4220794310C185592680 @default.
- W4220794310 hasConceptScore W4220794310C186060115 @default.
- W4220794310 hasConceptScore W4220794310C190283241 @default.
- W4220794310 hasConceptScore W4220794310C41625074 @default.
- W4220794310 hasConceptScore W4220794310C55493867 @default.
- W4220794310 hasConceptScore W4220794310C62520636 @default.
- W4220794310 hasConceptScore W4220794310C86803240 @default.
- W4220794310 hasConceptScore W4220794310C91881484 @default.
- W4220794310 hasConceptScore W4220794310C98539663 @default.
- W4220794310 hasIssue "2" @default.
- W4220794310 hasLocation W42207943101 @default.
- W4220794310 hasLocation W42207943102 @default.
- W4220794310 hasLocation W42207943103 @default.
- W4220794310 hasLocation W42207943104 @default.
- W4220794310 hasOpenAccess W4220794310 @default.
- W4220794310 hasPrimaryLocation W42207943101 @default.
- W4220794310 hasRelatedWork W2048400417 @default.
- W4220794310 hasRelatedWork W2050538415 @default.
- W4220794310 hasRelatedWork W2079739404 @default.
- W4220794310 hasRelatedWork W2088431388 @default.
- W4220794310 hasRelatedWork W2140725547 @default.
- W4220794310 hasRelatedWork W2801454733 @default.
- W4220794310 hasRelatedWork W2952110918 @default.
- W4220794310 hasRelatedWork W2977330715 @default.
- W4220794310 hasRelatedWork W3138279926 @default.
- W4220794310 hasRelatedWork W4297810403 @default.
- W4220794310 hasVolume "3" @default.
- W4220794310 isParatext "false" @default.
- W4220794310 isRetracted "false" @default.
- W4220794310 workType "article" @default.