Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220795003> ?p ?o ?g. }
- W4220795003 endingPage "184" @default.
- W4220795003 startingPage "176" @default.
- W4220795003 abstract "Background: Late-life depression (LLD) is one of the most common psychiatric disorders. However, LLD is often undetected or inadequately treated by clinicians. This review summarizes the recent research on pharmacotherapy for LLD, updates information on monotherapy using recommended antidepressants, and discusses the clinical features and diagnostic criteria for LLD.Current Concepts: The diagnostic criteria for depression in both elderly and young adults are identical. Clinical features of the elderly with depression more likely include more comorbid medical conditions and cognitive impairment than those of young adults. Depression in the elderly tends to have a more chronic course with frequent recurrences or relapses.Discussion and Conclusion: The current pharmacological treatment guidelines for LLD recommend the use of selective serotonin reuptake inhibitor (SSRI), serotonin-norepinephrine reuptake inhibitor, bupropion, mirtazapine, and vortioxetine as first-line medications. SSRIs, among them, are recommended first because they present fewer serious adverse effects and more clinical evidence than those of other antidepressants. Before starting antidepressant treatment for LLD, clinicians should consider patients’ comorbid medical conditions, drug interactions, possible adverse effects of antidepressants, and polypharmacy. The starting dose of antidepressants for elderly patients should be half of that prescribed for young adults to minimize the adverse effects; however, most elderly patients need the same antidepressant doses as that prescribed for young patients. After remission, a 1-year maintenance treatment is required to prevent recurrence or relapse of LLD." @default.
- W4220795003 created "2022-04-03" @default.
- W4220795003 creator A5047917981 @default.
- W4220795003 date "2022-03-10" @default.
- W4220795003 modified "2023-09-30" @default.
- W4220795003 title "Pharmacotherapy for late-life depression" @default.
- W4220795003 cites W1524088676 @default.
- W4220795003 cites W1819417743 @default.
- W4220795003 cites W1896306650 @default.
- W4220795003 cites W1969010569 @default.
- W4220795003 cites W1971088228 @default.
- W4220795003 cites W1980927992 @default.
- W4220795003 cites W1983082039 @default.
- W4220795003 cites W1987544980 @default.
- W4220795003 cites W2000818103 @default.
- W4220795003 cites W2014132062 @default.
- W4220795003 cites W2026961472 @default.
- W4220795003 cites W2043842622 @default.
- W4220795003 cites W2044095917 @default.
- W4220795003 cites W2049571898 @default.
- W4220795003 cites W2076277579 @default.
- W4220795003 cites W2079276291 @default.
- W4220795003 cites W2085709863 @default.
- W4220795003 cites W2102480288 @default.
- W4220795003 cites W2106332661 @default.
- W4220795003 cites W2118984041 @default.
- W4220795003 cites W2142827889 @default.
- W4220795003 cites W2155959499 @default.
- W4220795003 cites W2167534443 @default.
- W4220795003 cites W2171199381 @default.
- W4220795003 cites W2182675463 @default.
- W4220795003 cites W2489205254 @default.
- W4220795003 cites W2519531315 @default.
- W4220795003 cites W2538980438 @default.
- W4220795003 cites W2549071761 @default.
- W4220795003 cites W2576752247 @default.
- W4220795003 cites W2736307756 @default.
- W4220795003 cites W2795969245 @default.
- W4220795003 cites W2802098170 @default.
- W4220795003 cites W2902802331 @default.
- W4220795003 cites W2964643970 @default.
- W4220795003 cites W3158733857 @default.
- W4220795003 cites W4229883581 @default.
- W4220795003 cites W4253991700 @default.
- W4220795003 cites W4256632795 @default.
- W4220795003 doi "https://doi.org/10.5124/jkma.2022.65.3.176" @default.
- W4220795003 hasPublicationYear "2022" @default.
- W4220795003 type Work @default.
- W4220795003 citedByCount "0" @default.
- W4220795003 crossrefType "journal-article" @default.
- W4220795003 hasAuthorship W4220795003A5047917981 @default.
- W4220795003 hasBestOaLocation W42207950031 @default.
- W4220795003 hasConcept C118552586 @default.
- W4220795003 hasConcept C126322002 @default.
- W4220795003 hasConcept C139719470 @default.
- W4220795003 hasConcept C142724271 @default.
- W4220795003 hasConcept C162324750 @default.
- W4220795003 hasConcept C169900460 @default.
- W4220795003 hasConcept C197934379 @default.
- W4220795003 hasConcept C2776867660 @default.
- W4220795003 hasConcept C2777843972 @default.
- W4220795003 hasConcept C2778034309 @default.
- W4220795003 hasConcept C2778375690 @default.
- W4220795003 hasConcept C2779177272 @default.
- W4220795003 hasConcept C2779583969 @default.
- W4220795003 hasConcept C2779908668 @default.
- W4220795003 hasConcept C2780051608 @default.
- W4220795003 hasConcept C2780092697 @default.
- W4220795003 hasConcept C2780733359 @default.
- W4220795003 hasConcept C2781068410 @default.
- W4220795003 hasConcept C2781357127 @default.
- W4220795003 hasConcept C31487548 @default.
- W4220795003 hasConcept C36434225 @default.
- W4220795003 hasConcept C500440147 @default.
- W4220795003 hasConcept C558461103 @default.
- W4220795003 hasConcept C71924100 @default.
- W4220795003 hasConceptScore W4220795003C118552586 @default.
- W4220795003 hasConceptScore W4220795003C126322002 @default.
- W4220795003 hasConceptScore W4220795003C139719470 @default.
- W4220795003 hasConceptScore W4220795003C142724271 @default.
- W4220795003 hasConceptScore W4220795003C162324750 @default.
- W4220795003 hasConceptScore W4220795003C169900460 @default.
- W4220795003 hasConceptScore W4220795003C197934379 @default.
- W4220795003 hasConceptScore W4220795003C2776867660 @default.
- W4220795003 hasConceptScore W4220795003C2777843972 @default.
- W4220795003 hasConceptScore W4220795003C2778034309 @default.
- W4220795003 hasConceptScore W4220795003C2778375690 @default.
- W4220795003 hasConceptScore W4220795003C2779177272 @default.
- W4220795003 hasConceptScore W4220795003C2779583969 @default.
- W4220795003 hasConceptScore W4220795003C2779908668 @default.
- W4220795003 hasConceptScore W4220795003C2780051608 @default.
- W4220795003 hasConceptScore W4220795003C2780092697 @default.
- W4220795003 hasConceptScore W4220795003C2780733359 @default.
- W4220795003 hasConceptScore W4220795003C2781068410 @default.
- W4220795003 hasConceptScore W4220795003C2781357127 @default.
- W4220795003 hasConceptScore W4220795003C31487548 @default.
- W4220795003 hasConceptScore W4220795003C36434225 @default.
- W4220795003 hasConceptScore W4220795003C500440147 @default.