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• W4220796688 abstract "Amide proton transfer (APT) imaging, a variant of chemical exchange saturation transfer MRI, has shown promise in detecting ischemic tissue acidosis following impaired aerobic metabolism in animal models and in human stroke patients due to the sensitivity of the amide proton exchange rate to changes in pH within the physiological range. Recent studies have demonstrated the possibility of using APT-MRI to detect acidosis of the ischemic penumbra, enabling the assessment of stroke severity and risk of progression, monitoring of treatment progress, and prognostication of clinical outcome. This paper reviews current APT imaging methods actively used in ischemic stroke research and explores the clinical aspects of ischemic stroke and future applications for these methods." @default.
• W4220796688 created "2022-04-03" @default.
• W4220796688 creator A5001596439 @default.
• W4220796688 creator A5016748099 @default.
• W4220796688 creator A5062031603 @default.
• W4220796688 creator A5071996865 @default.
• W4220796688 creator A5078041599 @default.
• W4220796688 date "2022-04-10" @default.
• W4220796688 modified "2023-10-12" @default.
• W4220796688 title "Amide proton transfer imaging in stroke" @default.
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