FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220801634> ?p ?o ?g. }

• W4220801634 abstract "Cell-to-cell communication within the heterogeneous solid tumor environment plays a significant role in the uncontrolled metastasis of cancer. To inhibit the metastasis and growth of cancer cells, various chemically designed and biologically derived nanosized biomaterials have been applied for targeted cancer therapeutics applications. Over the years, bioinspired soft nanovesicles have gained tremendous attention for targeted cancer therapeutics due to their easy binding with tumor microenvironment, natural targeting ability, bio-responsive nature, better biocompatibility, high cargo capacity for multiple therapeutics agents, and long circulation time. These cell-derived nanovesicles guard their loaded cargo molecules from immune clearance and make them site-selective to cancer cells due to their natural binding and delivery abilities. Furthermore, bioinspired soft nanovesicles prevent cell-to-cell communication and secretion of cancer cell markers by delivering the therapeutics agents predominantly. Cell-derived vesicles, namely, exosomes, extracellular vesicles, and so forth have been recognized as versatile carriers for therapeutic biomolecules. However, low product yield, poor reproducibility, and uncontrolled particle size distribution have remained as major challenges of these soft nanovesicles. Furthermore, the surface biomarkers and molecular contents of these vesicles change with respect to the stage of disease and types. Here in this review, we have discussed numerous examples of bioinspired soft vesicles for targeted imaging and cancer therapeutic applications with their advantages and limitations. Importance of bioengineered soft nanovesicles for localized therapies with their clinical relevance has also been addressed in this article. Overall, cell-derived nanovesicles could be considered as clinically relevant platforms for cancer therapeutics. This article is categorized under: Biology-Inspired Nanomaterials > Nucleic Acid-Based Structures Therapeutic Approaches and Drug Discovery > Nanomedicine for Oncologic Disease." @default.
• W4220801634 created "2022-04-03" @default.
• W4220801634 creator A5054197081 @default.
• W4220801634 creator A5058199128 @default.
• W4220801634 date "2022-03-22" @default.
• W4220801634 modified "2023-10-16" @default.
• W4220801634 title "Bioinspired soft nanovesicles for site‐selective cancer imaging and targeted therapies" @default.
• W4220801634 cites W1980052502 @default.
• W4220801634 cites W1984557698 @default.
• W4220801634 cites W1987604193 @default.
• W4220801634 cites W2002019410 @default.
• W4220801634 cites W2015013205 @default.
• W4220801634 cites W2016285930 @default.
• W4220801634 cites W2030701238 @default.
• W4220801634 cites W2034774921 @default.
• W4220801634 cites W2045574035 @default.
• W4220801634 cites W2054410308 @default.
• W4220801634 cites W2054847598 @default.
• W4220801634 cites W2059767791 @default.
• W4220801634 cites W2066843867 @default.
• W4220801634 cites W2075668934 @default.
• W4220801634 cites W2083241168 @default.
• W4220801634 cites W2087487150 @default.
• W4220801634 cites W2093013992 @default.
• W4220801634 cites W2097343453 @default.
• W4220801634 cites W2133897272 @default.
• W4220801634 cites W2153294383 @default.
• W4220801634 cites W2157139123 @default.
• W4220801634 cites W2166846320 @default.
• W4220801634 cites W2167844952 @default.
• W4220801634 cites W2176301470 @default.
• W4220801634 cites W2194502287 @default.
• W4220801634 cites W2205539453 @default.
• W4220801634 cites W2239440945 @default.
• W4220801634 cites W2283764701 @default.
• W4220801634 cites W2290419157 @default.
• W4220801634 cites W2291842431 @default.
• W4220801634 cites W2295224762 @default.
• W4220801634 cites W2300671107 @default.
• W4220801634 cites W2309770165 @default.
• W4220801634 cites W2337502608 @default.
• W4220801634 cites W2491353610 @default.
• W4220801634 cites W2493414058 @default.
• W4220801634 cites W2522754433 @default.
• W4220801634 cites W2554773181 @default.
• W4220801634 cites W2556664795 @default.
• W4220801634 cites W2567639438 @default.
• W4220801634 cites W2569144642 @default.
• W4220801634 cites W2569453488 @default.
• W4220801634 cites W2585509655 @default.
• W4220801634 cites W2587710699 @default.
• W4220801634 cites W2588173448 @default.
• W4220801634 cites W2588703017 @default.
• W4220801634 cites W2592666178 @default.
• W4220801634 cites W2593910260 @default.
• W4220801634 cites W2599276599 @default.
• W4220801634 cites W2605172395 @default.
• W4220801634 cites W2617507069 @default.
• W4220801634 cites W2622414879 @default.
• W4220801634 cites W2670652826 @default.
• W4220801634 cites W2727426256 @default.
• W4220801634 cites W2728985030 @default.
• W4220801634 cites W2735818385 @default.
• W4220801634 cites W2742498892 @default.
• W4220801634 cites W2745137260 @default.
• W4220801634 cites W2745610816 @default.
• W4220801634 cites W2753961578 @default.
• W4220801634 cites W2754938970 @default.
• W4220801634 cites W2757807906 @default.
• W4220801634 cites W2765148841 @default.
• W4220801634 cites W2767708997 @default.
• W4220801634 cites W2769263776 @default.
• W4220801634 cites W2779044993 @default.
• W4220801634 cites W2782420369 @default.
• W4220801634 cites W2783823932 @default.
• W4220801634 cites W2783878221 @default.
• W4220801634 cites W2783883933 @default.
• W4220801634 cites W2783970300 @default.
• W4220801634 cites W2786202610 @default.
• W4220801634 cites W2787077101 @default.
• W4220801634 cites W2787356256 @default.
• W4220801634 cites W2788820366 @default.
• W4220801634 cites W2789520246 @default.
• W4220801634 cites W2791490604 @default.
• W4220801634 cites W2793798811 @default.
• W4220801634 cites W2795072156 @default.
• W4220801634 cites W2795139701 @default.
• W4220801634 cites W2796631501 @default.
• W4220801634 cites W2800127497 @default.
• W4220801634 cites W2804826922 @default.
• W4220801634 cites W2807567618 @default.
• W4220801634 cites W2808745288 @default.
• W4220801634 cites W2808830750 @default.
• W4220801634 cites W2809359228 @default.
• W4220801634 cites W2810059531 @default.
• W4220801634 cites W2847081133 @default.
• W4220801634 cites W2886481736 @default.
• W4220801634 cites W2889201386 @default.
• W4220801634 cites W2891141728 @default.
• W4220801634 cites W2891730151 @default.

• next