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- W4220803257 endingPage "100253" @default.
- W4220803257 startingPage "100253" @default.
- W4220803257 abstract ": The extracts of Garcinia mangostana (L) pericarp contain high concentration of prenylated xanthones such as α-, β- and γ-mangostin and related molecules. These extracts possess wide range of biological properties including anticancer, anti-inflammatory, anti-proliferative, antioxidant and pro-apoptotic activities. Till date, α-, β- and γ-mangostin have been extensively studied due to its applications in nutritional supplements, herbal cosmetics and pharmaceutical preparations, but only a few attempts were being made to explore the synthetic utility of these abundantly distributed xanthones. : The data were obtained from several database such as Scopus, Pubmed and Sciencefinder. : This review provides an overview of the synthesis and ethnomedicinal uses of major xanthones, including α, β, andγ-mangostin, gartanin, and tovophyllin B, isolated and identified from the pericarp of the species G. mangostana. The biological and synthetic applications of the compounds obtained after the chemical modification of core xanthone skeleton of major mangostin compounds are also presented in this review. Currently available α-mangostin containing food products, their clinical, pharmacokinetic and safety studies are described. : The main focus of the review is the use of naturally occurring α-, β- and γ-mangostin and their derivatives, as promising scaffolds for new drug discovery." @default.
- W4220803257 created "2022-04-03" @default.
- W4220803257 creator A5003429116 @default.
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- W4220803257 creator A5031937045 @default.
- W4220803257 creator A5035239347 @default.
- W4220803257 creator A5035750388 @default.
- W4220803257 date "2022-05-01" @default.
- W4220803257 modified "2023-10-13" @default.
- W4220803257 title "A Review on Synthetic and Pharmacological Potential of Compounds Isolated from Garcinia mangostana Linn" @default.
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