FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220804737> ?p ?o ?g. }

• W4220804737 abstract "A major question in clinical science is how to study the natural course of a chronic disease from inception to end, which is challenging because it is impractical to follow patients over decades. Here, we developed BETR (Bayesian entry time realignment), a hierarchical Bayesian method for investigating the long-term natural history of diseases using data from patients followed over short durations. A simulation study shows that BETR outperforms an existing method that ignores patient-level variation in progression rates. BETR, when combined with a common Bayesian model comparison tool, can identify the correct disease progression function nearly 100% of the time, with high accuracy in estimating the individual disease durations and progression rates. Application of BETR in patients with geographic atrophy, a disease with a known natural history model, shows that it can identify the correct disease progression model. Applying BETR in patients with Huntington's disease demonstrates that the progression of motor symptoms follows a second order function over approximately 20 years." @default.
• W4220804737 created "2022-04-03" @default.
• W4220804737 creator A5022127687 @default.
• W4220804737 creator A5034104351 @default.
• W4220804737 creator A5071981247 @default.
• W4220804737 date "2022-03-22" @default.
• W4220804737 modified "2023-09-25" @default.
• W4220804737 title "A hierarchical Bayesian entry time realignment method to study the long-term natural history of diseases" @default.
• W4220804737 cites W1500026344 @default.
• W4220804737 cites W1518897246 @default.
• W4220804737 cites W1934543195 @default.
• W4220804737 cites W1970134158 @default.
• W4220804737 cites W1970842038 @default.
• W4220804737 cites W1973907181 @default.
• W4220804737 cites W2029638099 @default.
• W4220804737 cites W2049823525 @default.
• W4220804737 cites W2057765075 @default.
• W4220804737 cites W2067003762 @default.
• W4220804737 cites W2081268901 @default.
• W4220804737 cites W2102729801 @default.
• W4220804737 cites W2104764481 @default.
• W4220804737 cites W2106585690 @default.
• W4220804737 cites W2112675961 @default.
• W4220804737 cites W2136381651 @default.
• W4220804737 cites W2139906402 @default.
• W4220804737 cites W2140599670 @default.
• W4220804737 cites W2155675678 @default.
• W4220804737 cites W2160226180 @default.
• W4220804737 cites W2163671213 @default.
• W4220804737 cites W2168122879 @default.
• W4220804737 cites W2313055258 @default.
• W4220804737 cites W2397760225 @default.
• W4220804737 cites W2475026798 @default.
• W4220804737 cites W2507763988 @default.
• W4220804737 cites W2522663397 @default.
• W4220804737 cites W2566154985 @default.
• W4220804737 cites W2580035316 @default.
• W4220804737 cites W2598520882 @default.
• W4220804737 cites W2789826689 @default.
• W4220804737 cites W2791040794 @default.
• W4220804737 cites W2801421710 @default.
• W4220804737 cites W2802822211 @default.
• W4220804737 cites W2883601524 @default.
• W4220804737 cites W2904545488 @default.
• W4220804737 cites W2921324754 @default.
• W4220804737 cites W2946498074 @default.
• W4220804737 cites W2959393635 @default.
• W4220804737 cites W3011844773 @default.
• W4220804737 cites W3014593787 @default.
• W4220804737 cites W3015186627 @default.
• W4220804737 cites W3029055343 @default.
• W4220804737 cites W3037747983 @default.
• W4220804737 cites W3045891726 @default.
• W4220804737 cites W3081661825 @default.
• W4220804737 cites W3102831288 @default.
• W4220804737 cites W310903783 @default.
• W4220804737 cites W3111675991 @default.
• W4220804737 cites W3122858766 @default.
• W4220804737 doi "https://doi.org/10.1038/s41598-022-08919-1" @default.
• W4220804737 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35318383" @default.
• W4220804737 hasPublicationYear "2022" @default.
• W4220804737 type Work @default.
• W4220804737 citedByCount "1" @default.
• W4220804737 countsByYear W42208047372023 @default.
• W4220804737 crossrefType "journal-article" @default.
• W4220804737 hasAuthorship W4220804737A5022127687 @default.
• W4220804737 hasAuthorship W4220804737A5034104351 @default.
• W4220804737 hasAuthorship W4220804737A5071981247 @default.
• W4220804737 hasBestOaLocation W42208047371 @default.
• W4220804737 hasConcept C105795698 @default.
• W4220804737 hasConcept C107673813 @default.
• W4220804737 hasConcept C121332964 @default.
• W4220804737 hasConcept C126322002 @default.
• W4220804737 hasConcept C14036430 @default.
• W4220804737 hasConcept C151730666 @default.
• W4220804737 hasConcept C154945302 @default.
• W4220804737 hasConcept C160234255 @default.
• W4220804737 hasConcept C163276114 @default.
• W4220804737 hasConcept C191413810 @default.
• W4220804737 hasConcept C2776608160 @default.
• W4220804737 hasConcept C2779134260 @default.
• W4220804737 hasConcept C33923547 @default.
• W4220804737 hasConcept C41008148 @default.
• W4220804737 hasConcept C61797465 @default.
• W4220804737 hasConcept C62520636 @default.
• W4220804737 hasConcept C71924100 @default.
• W4220804737 hasConcept C78458016 @default.
• W4220804737 hasConcept C86803240 @default.
• W4220804737 hasConceptScore W4220804737C105795698 @default.
• W4220804737 hasConceptScore W4220804737C107673813 @default.
• W4220804737 hasConceptScore W4220804737C121332964 @default.
• W4220804737 hasConceptScore W4220804737C126322002 @default.
• W4220804737 hasConceptScore W4220804737C14036430 @default.
• W4220804737 hasConceptScore W4220804737C151730666 @default.
• W4220804737 hasConceptScore W4220804737C154945302 @default.
• W4220804737 hasConceptScore W4220804737C160234255 @default.
• W4220804737 hasConceptScore W4220804737C163276114 @default.
• W4220804737 hasConceptScore W4220804737C191413810 @default.
• W4220804737 hasConceptScore W4220804737C2776608160 @default.
• W4220804737 hasConceptScore W4220804737C2779134260 @default.

• next