Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220804853> ?p ?o ?g. }
- W4220804853 endingPage "114225" @default.
- W4220804853 startingPage "114225" @default.
- W4220804853 abstract "Gastrointestinal fistula, a complication of gastrointestinal cancer surgery, has a high mortality rate. Detection of both C-reactive protein (CRP) and prealbumin (PAB) is advantageous in the auxiliary diagnosis of postoperative complications. However, traditional detection methods are not capable of on-site rapid detection. In an attempt to overcome these challenges, a multifunctional origami-paper-based device (ePADs) was developed to simultaneously detect CRP and PAB in whole blood. After integration, functionalization, and modification, the electrochemical dual-parameter device was capable of separating blood cells and detecting target analytes. The plasma separation performance revealed a sample diffusion time of 75 s for a whole blood sample volume of 73.3 μL. The efficiency of the device in separating blood cells was 99.91%. Electrochemical results showed that the multifunctional device exhibited linearity between 5 pg mL-1 and 1 μg mL-1 for CRP (R2 = 0.990), and between 10 pg mL-1 and 1 μg mL-1 for PAB (R2 = 0.998). The limits of detection for CRP and PAB were 5 and 10 pg mL-1, respectively (S/N = 3). We also successfully evaluated the accuracy of the dual-parameter device with clinical whole blood samples. Based on these results, the multifunctional device can facilitate clinical detection and provide a new platform for domestic point-of-care testing." @default.
- W4220804853 created "2022-04-03" @default.
- W4220804853 creator A5009771110 @default.
- W4220804853 creator A5010934355 @default.
- W4220804853 creator A5022242648 @default.
- W4220804853 creator A5032539204 @default.
- W4220804853 creator A5035726040 @default.
- W4220804853 creator A5038288893 @default.
- W4220804853 creator A5042591538 @default.
- W4220804853 creator A5043616119 @default.
- W4220804853 creator A5047268788 @default.
- W4220804853 creator A5055363528 @default.
- W4220804853 creator A5059799647 @default.
- W4220804853 creator A5085701664 @default.
- W4220804853 date "2022-07-01" @default.
- W4220804853 modified "2023-10-13" @default.
- W4220804853 title "Multifunctional self-driven origami paper-based integrated microfluidic chip to detect CRP and PAB in whole blood" @default.
- W4220804853 cites W1852242903 @default.
- W4220804853 cites W1965365753 @default.
- W4220804853 cites W1970275997 @default.
- W4220804853 cites W1971690592 @default.
- W4220804853 cites W1974074647 @default.
- W4220804853 cites W1984642274 @default.
- W4220804853 cites W1986039194 @default.
- W4220804853 cites W1990221095 @default.
- W4220804853 cites W2005344302 @default.
- W4220804853 cites W2010780711 @default.
- W4220804853 cites W2012717558 @default.
- W4220804853 cites W2019397264 @default.
- W4220804853 cites W2024035178 @default.
- W4220804853 cites W2025491055 @default.
- W4220804853 cites W2030102157 @default.
- W4220804853 cites W2038336578 @default.
- W4220804853 cites W2038907514 @default.
- W4220804853 cites W2052287876 @default.
- W4220804853 cites W2066978845 @default.
- W4220804853 cites W2072295131 @default.
- W4220804853 cites W2075296706 @default.
- W4220804853 cites W2095052940 @default.
- W4220804853 cites W2125448535 @default.
- W4220804853 cites W2160727579 @default.
- W4220804853 cites W2160738932 @default.
- W4220804853 cites W2170393995 @default.
- W4220804853 cites W2177699277 @default.
- W4220804853 cites W2606250977 @default.
- W4220804853 cites W2808328829 @default.
- W4220804853 cites W2954980818 @default.
- W4220804853 cites W2999592980 @default.
- W4220804853 cites W3124034163 @default.
- W4220804853 cites W4212902526 @default.
- W4220804853 doi "https://doi.org/10.1016/j.bios.2022.114225" @default.
- W4220804853 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35358776" @default.
- W4220804853 hasPublicationYear "2022" @default.
- W4220804853 type Work @default.
- W4220804853 citedByCount "15" @default.
- W4220804853 countsByYear W42208048532022 @default.
- W4220804853 countsByYear W42208048532023 @default.
- W4220804853 crossrefType "journal-article" @default.
- W4220804853 hasAuthorship W4220804853A5009771110 @default.
- W4220804853 hasAuthorship W4220804853A5010934355 @default.
- W4220804853 hasAuthorship W4220804853A5022242648 @default.
- W4220804853 hasAuthorship W4220804853A5032539204 @default.
- W4220804853 hasAuthorship W4220804853A5035726040 @default.
- W4220804853 hasAuthorship W4220804853A5038288893 @default.
- W4220804853 hasAuthorship W4220804853A5042591538 @default.
- W4220804853 hasAuthorship W4220804853A5043616119 @default.
- W4220804853 hasAuthorship W4220804853A5047268788 @default.
- W4220804853 hasAuthorship W4220804853A5055363528 @default.
- W4220804853 hasAuthorship W4220804853A5059799647 @default.
- W4220804853 hasAuthorship W4220804853A5085701664 @default.
- W4220804853 hasConcept C10390740 @default.
- W4220804853 hasConcept C119128265 @default.
- W4220804853 hasConcept C136229726 @default.
- W4220804853 hasConcept C138942068 @default.
- W4220804853 hasConcept C141071460 @default.
- W4220804853 hasConcept C142724271 @default.
- W4220804853 hasConcept C1621761 @default.
- W4220804853 hasConcept C171250308 @default.
- W4220804853 hasConcept C185592680 @default.
- W4220804853 hasConcept C192562407 @default.
- W4220804853 hasConcept C43617362 @default.
- W4220804853 hasConcept C51915194 @default.
- W4220804853 hasConcept C71924100 @default.
- W4220804853 hasConcept C8673954 @default.
- W4220804853 hasConceptScore W4220804853C10390740 @default.
- W4220804853 hasConceptScore W4220804853C119128265 @default.
- W4220804853 hasConceptScore W4220804853C136229726 @default.
- W4220804853 hasConceptScore W4220804853C138942068 @default.
- W4220804853 hasConceptScore W4220804853C141071460 @default.
- W4220804853 hasConceptScore W4220804853C142724271 @default.
- W4220804853 hasConceptScore W4220804853C1621761 @default.
- W4220804853 hasConceptScore W4220804853C171250308 @default.
- W4220804853 hasConceptScore W4220804853C185592680 @default.
- W4220804853 hasConceptScore W4220804853C192562407 @default.
- W4220804853 hasConceptScore W4220804853C43617362 @default.
- W4220804853 hasConceptScore W4220804853C51915194 @default.
- W4220804853 hasConceptScore W4220804853C71924100 @default.
- W4220804853 hasConceptScore W4220804853C8673954 @default.