Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220806549> ?p ?o ?g. }
- W4220806549 endingPage "3266" @default.
- W4220806549 startingPage "3266" @default.
- W4220806549 abstract "Under metabolic stress conditions, there is a higher demand for nutrients which needs to be met. This is to reduce the risk of delay in wound healing which could lead to chronic wound.This is a systematic review of the effect of Centella asiatica on wound healing. C. asiatica is a traditional medicinal plant used due to its antimicrobial, antioxidant, anti-inflammatory, neuroprotective, and wound healing properties.PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines were followed for the systematic review and four electronic databases were used.Four clinical trials met the inclusion criteria. The following distinct areas were identified under C. asiatica: wound contraction and granulation; healing/bleeding time and re-epithelialization; VAS (visual analogue scale) scores; skin erythema and wound appearance.C. asiatica might enhance wound healing resulting from improved angiogenesis. This might occur due to its stimulating effect on collagen I, Fibroblast Growth Factor (FGF) and Vascular Endothelial Growth Factor (VEGF) production. Besides, C. asiatica has shown an anti-inflammatory effect observed by the reduction in Interleukin-1β (IL-1β), Interleukin-6 (IL-6) and Tumour Necrosis Factor α (TNFα), prostaglandin E2 (PGE2), cyclooxygenase-2 (COX-2), and lipoxygenase (LOX) activity. Delivery systems such as nanoencapsulation could be used to increase C. asiatica bioavailability. Nevertheless, more studies are needed in order to perform a meta-analysis and ascertain the effects of C. asiatica on wound healing and its different parameters." @default.
- W4220806549 created "2022-04-03" @default.
- W4220806549 creator A5022093260 @default.
- W4220806549 creator A5024963282 @default.
- W4220806549 creator A5028520116 @default.
- W4220806549 creator A5054341672 @default.
- W4220806549 creator A5056939779 @default.
- W4220806549 date "2022-03-10" @default.
- W4220806549 modified "2023-10-05" @default.
- W4220806549 title "A Systematic Review of the Effect of Centella asiatica on Wound Healing" @default.
- W4220806549 cites W134442714 @default.
- W4220806549 cites W1537904705 @default.
- W4220806549 cites W1598910025 @default.
- W4220806549 cites W177296155 @default.
- W4220806549 cites W1796374197 @default.
- W4220806549 cites W1952455177 @default.
- W4220806549 cites W1965225492 @default.
- W4220806549 cites W1975367425 @default.
- W4220806549 cites W1976505302 @default.
- W4220806549 cites W1982102893 @default.
- W4220806549 cites W1989354404 @default.
- W4220806549 cites W1992396801 @default.
- W4220806549 cites W1996838400 @default.
- W4220806549 cites W2007187686 @default.
- W4220806549 cites W2007584755 @default.
- W4220806549 cites W2013284753 @default.
- W4220806549 cites W2015045330 @default.
- W4220806549 cites W2016039768 @default.
- W4220806549 cites W2025138472 @default.
- W4220806549 cites W2030281917 @default.
- W4220806549 cites W2033327918 @default.
- W4220806549 cites W2041000069 @default.
- W4220806549 cites W2046643614 @default.
- W4220806549 cites W2051827697 @default.
- W4220806549 cites W2054894799 @default.
- W4220806549 cites W2060547700 @default.
- W4220806549 cites W2063509394 @default.
- W4220806549 cites W2066886841 @default.
- W4220806549 cites W2070854535 @default.
- W4220806549 cites W2071030426 @default.
- W4220806549 cites W2074570728 @default.
- W4220806549 cites W2081168487 @default.
- W4220806549 cites W2081206066 @default.
- W4220806549 cites W2091900972 @default.
- W4220806549 cites W2105698780 @default.
- W4220806549 cites W2117677679 @default.
- W4220806549 cites W2124211842 @default.
- W4220806549 cites W2129935236 @default.
- W4220806549 cites W2135004329 @default.
- W4220806549 cites W2143088276 @default.
- W4220806549 cites W2144885000 @default.
- W4220806549 cites W2146567239 @default.
- W4220806549 cites W2158627298 @default.
- W4220806549 cites W2161374186 @default.
- W4220806549 cites W2229330024 @default.
- W4220806549 cites W2257112832 @default.
- W4220806549 cites W2271141756 @default.
- W4220806549 cites W2319578554 @default.
- W4220806549 cites W2325727928 @default.
- W4220806549 cites W2414183004 @default.
- W4220806549 cites W2416654538 @default.
- W4220806549 cites W2419329333 @default.
- W4220806549 cites W2548516545 @default.
- W4220806549 cites W2564121620 @default.
- W4220806549 cites W2593644476 @default.
- W4220806549 cites W2757842045 @default.
- W4220806549 cites W2761666761 @default.
- W4220806549 cites W2780153520 @default.
- W4220806549 cites W2810688187 @default.
- W4220806549 cites W2901135781 @default.
- W4220806549 cites W2902282736 @default.
- W4220806549 cites W2910936075 @default.
- W4220806549 cites W2913930991 @default.
- W4220806549 cites W2923001015 @default.
- W4220806549 cites W2967186907 @default.
- W4220806549 cites W2978795816 @default.
- W4220806549 cites W2982354660 @default.
- W4220806549 cites W2996456637 @default.
- W4220806549 cites W3003302043 @default.
- W4220806549 cites W3006578543 @default.
- W4220806549 cites W3016590679 @default.
- W4220806549 cites W3131411982 @default.
- W4220806549 cites W3143240125 @default.
- W4220806549 cites W3184400565 @default.
- W4220806549 cites W3199798879 @default.
- W4220806549 cites W3200144739 @default.
- W4220806549 cites W341595330 @default.
- W4220806549 cites W4231083159 @default.
- W4220806549 cites W4234878332 @default.
- W4220806549 cites W4235608700 @default.
- W4220806549 cites W2462389059 @default.
- W4220806549 cites W3198970443 @default.
- W4220806549 doi "https://doi.org/10.3390/ijerph19063266" @default.
- W4220806549 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35328954" @default.
- W4220806549 hasPublicationYear "2022" @default.
- W4220806549 type Work @default.
- W4220806549 citedByCount "17" @default.
- W4220806549 countsByYear W42208065492022 @default.