Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220807548> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W4220807548 endingPage "525" @default.
- W4220807548 startingPage "525" @default.
- W4220807548 abstract "A unique case of multiple metastatic melanoma skin nodules regression in a heavily pretreated, 72-year-old Caucasian female, after administering the second dose of the SARS-CoV-2 mRNA Pfizer-BioNTech vaccine, is presented. Two days after vaccination, all her melanoma skin nodules became painful and were significantly reduced in size. Physical examination and ultrasound imaging confirmed the patient's observation. The effect was sustained, and further reduction of the nodules occurred after the third vaccine dose. One of the reduced nodules was removed, histologically examined, and its histopathology was compared to that of another such nodule removed and examined earlier. Distinct differences were observed between the two histopathologies, with the most notable the unexpected finding of the absence of infiltrating lymphocytes in the reducer nodule's melanoma tissue. Based on this observation, the possible immunological mechanism(s) leading to the vaccine's effect are speculated. More possible is the vaccine's antitumor and apoptotic activity via stimulation of the Tol Like Receptors 3, 7, and 8, and (downstream) the nuclear factor kappa-light-chain-enhancer of the activated B cells pathway of the non-lymphocytic immune effector cells." @default.
- W4220807548 created "2022-04-03" @default.
- W4220807548 creator A5010312876 @default.
- W4220807548 creator A5018787724 @default.
- W4220807548 creator A5042908077 @default.
- W4220807548 creator A5055382737 @default.
- W4220807548 creator A5063879180 @default.
- W4220807548 creator A5070211460 @default.
- W4220807548 creator A5077026001 @default.
- W4220807548 date "2022-03-28" @default.
- W4220807548 modified "2023-10-18" @default.
- W4220807548 title "Therapeutic Effect of mRNA SARS-CoV-2 Vaccine on Melanoma Skin Metastases" @default.
- W4220807548 cites W2532791459 @default.
- W4220807548 cites W2536529113 @default.
- W4220807548 cites W2618081269 @default.
- W4220807548 cites W2965873243 @default.
- W4220807548 cites W2978554061 @default.
- W4220807548 cites W3006719485 @default.
- W4220807548 cites W3130729977 @default.
- W4220807548 cites W3133745688 @default.
- W4220807548 cites W3139530191 @default.
- W4220807548 cites W3140979803 @default.
- W4220807548 cites W3156114568 @default.
- W4220807548 cites W3172878008 @default.
- W4220807548 doi "https://doi.org/10.3390/vaccines10040525" @default.
- W4220807548 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35455274" @default.
- W4220807548 hasPublicationYear "2022" @default.
- W4220807548 type Work @default.
- W4220807548 citedByCount "0" @default.
- W4220807548 crossrefType "journal-article" @default.
- W4220807548 hasAuthorship W4220807548A5010312876 @default.
- W4220807548 hasAuthorship W4220807548A5018787724 @default.
- W4220807548 hasAuthorship W4220807548A5042908077 @default.
- W4220807548 hasAuthorship W4220807548A5055382737 @default.
- W4220807548 hasAuthorship W4220807548A5063879180 @default.
- W4220807548 hasAuthorship W4220807548A5070211460 @default.
- W4220807548 hasAuthorship W4220807548A5077026001 @default.
- W4220807548 hasBestOaLocation W42208075481 @default.
- W4220807548 hasConcept C142724271 @default.
- W4220807548 hasConcept C151730666 @default.
- W4220807548 hasConcept C203014093 @default.
- W4220807548 hasConcept C2776731575 @default.
- W4220807548 hasConcept C2777658100 @default.
- W4220807548 hasConcept C2777701055 @default.
- W4220807548 hasConcept C502942594 @default.
- W4220807548 hasConcept C544855455 @default.
- W4220807548 hasConcept C71924100 @default.
- W4220807548 hasConcept C86803240 @default.
- W4220807548 hasConcept C8891405 @default.
- W4220807548 hasConceptScore W4220807548C142724271 @default.
- W4220807548 hasConceptScore W4220807548C151730666 @default.
- W4220807548 hasConceptScore W4220807548C203014093 @default.
- W4220807548 hasConceptScore W4220807548C2776731575 @default.
- W4220807548 hasConceptScore W4220807548C2777658100 @default.
- W4220807548 hasConceptScore W4220807548C2777701055 @default.
- W4220807548 hasConceptScore W4220807548C502942594 @default.
- W4220807548 hasConceptScore W4220807548C544855455 @default.
- W4220807548 hasConceptScore W4220807548C71924100 @default.
- W4220807548 hasConceptScore W4220807548C86803240 @default.
- W4220807548 hasConceptScore W4220807548C8891405 @default.
- W4220807548 hasIssue "4" @default.
- W4220807548 hasLocation W42208075481 @default.
- W4220807548 hasLocation W42208075482 @default.
- W4220807548 hasLocation W42208075483 @default.
- W4220807548 hasLocation W42208075484 @default.
- W4220807548 hasOpenAccess W4220807548 @default.
- W4220807548 hasPrimaryLocation W42208075481 @default.
- W4220807548 hasRelatedWork W1513981329 @default.
- W4220807548 hasRelatedWork W2021968456 @default.
- W4220807548 hasRelatedWork W2068861579 @default.
- W4220807548 hasRelatedWork W2156639344 @default.
- W4220807548 hasRelatedWork W2399975507 @default.
- W4220807548 hasRelatedWork W2404659387 @default.
- W4220807548 hasRelatedWork W2412245334 @default.
- W4220807548 hasRelatedWork W2921749183 @default.
- W4220807548 hasRelatedWork W2981372661 @default.
- W4220807548 hasRelatedWork W4378799413 @default.
- W4220807548 hasVolume "10" @default.
- W4220807548 isParatext "false" @default.
- W4220807548 isRetracted "false" @default.
- W4220807548 workType "article" @default.