Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220817852> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W4220817852 endingPage "100994" @default.
- W4220817852 startingPage "100994" @default.
- W4220817852 abstract "The impact of anemia on the safety and efficacy of anticoagulants in elderly patients with atrial fibrillation (AF) has not been elucidated.The J-ELD AF Registry is a large-scale, multicenter prospective observational study, of the one-year outcomes after administration of on-label doses of apixaban in Japanese patients with non-valvular AF aged ≥ 75 years. The entire cohort (3,015 patients from 110 institutions) was divided into three subgroups according to the WHO classification of anemia: normal (hemoglobin ≥ 13.0 g/dL in men and ≥ 12.0 g/dL in women, n = 1733, 57.5%), mild anemia (11.0 ≤ hemoglobin < 13.0 g/dL in men and 11.0 ≤ hemoglobin < 12.0 g/dL in women, n = 839, 27.8%), and moderate-severe anemia (<11.0 g/dL in both men and women, n = 443, 14.7%). The event rates (/100 person-years) for the normal, mild anemia, and moderate-severe anemia groups were 1.36, 1.81, and 1.99 for strokes or systemic embolisms (log-rank p = 0.556), 1.74, 1.16, and 4.02 for bleeding requiring hospitalization (log-rank p = 0.007), 2.03, 3.72, and 6.44 for total death (log-rank p < 0.001), and 0.86, 1.03, and 1.24 for cardiovascular death (log-rank p = 0.770), respectively. After adjusting for the confounders, moderate-severe anemia was an independent risk of total death (hazard ratio [95% confidence interval]; 2.21 [1.28-3.81], P = 0.004), but not for strokes or systemic embolisms and bleeding.In AF patients aged ≥ 75 years taking an on-label dose of apixaban, moderate-severe anemia was not an independent risk of a stroke or systemic embolism and bleeding requiring hospitalization." @default.
- W4220817852 created "2022-04-03" @default.
- W4220817852 creator A5003552543 @default.
- W4220817852 creator A5005886945 @default.
- W4220817852 creator A5013562188 @default.
- W4220817852 creator A5022030714 @default.
- W4220817852 creator A5027412987 @default.
- W4220817852 creator A5049340312 @default.
- W4220817852 creator A5055983723 @default.
- W4220817852 creator A5072977591 @default.
- W4220817852 date "2022-06-01" @default.
- W4220817852 modified "2023-10-01" @default.
- W4220817852 title "Impact of anemia on the clinical outcomes in elderly patients with atrial fibrillation receiving apixaban: J-ELD AF registry subanalysis" @default.
- W4220817852 cites W1829866114 @default.
- W4220817852 cites W1984553148 @default.
- W4220817852 cites W2029045834 @default.
- W4220817852 cites W2063064549 @default.
- W4220817852 cites W2073063260 @default.
- W4220817852 cites W2096246254 @default.
- W4220817852 cites W2097854437 @default.
- W4220817852 cites W2106809715 @default.
- W4220817852 cites W2136489990 @default.
- W4220817852 cites W2162508946 @default.
- W4220817852 cites W2162586165 @default.
- W4220817852 cites W2567468616 @default.
- W4220817852 cites W2768169449 @default.
- W4220817852 cites W2913217706 @default.
- W4220817852 cites W2921813015 @default.
- W4220817852 cites W2983069756 @default.
- W4220817852 cites W2991651199 @default.
- W4220817852 cites W3004467131 @default.
- W4220817852 cites W3017342315 @default.
- W4220817852 cites W3032455792 @default.
- W4220817852 cites W3049214946 @default.
- W4220817852 cites W3124410225 @default.
- W4220817852 cites W3203099168 @default.
- W4220817852 cites W4230970026 @default.
- W4220817852 cites W4300771061 @default.
- W4220817852 doi "https://doi.org/10.1016/j.ijcha.2022.100994" @default.
- W4220817852 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35342786" @default.
- W4220817852 hasPublicationYear "2022" @default.
- W4220817852 type Work @default.
- W4220817852 citedByCount "3" @default.
- W4220817852 countsByYear W42208178522022 @default.
- W4220817852 countsByYear W42208178522023 @default.
- W4220817852 crossrefType "journal-article" @default.
- W4220817852 hasAuthorship W4220817852A5003552543 @default.
- W4220817852 hasAuthorship W4220817852A5005886945 @default.
- W4220817852 hasAuthorship W4220817852A5013562188 @default.
- W4220817852 hasAuthorship W4220817852A5022030714 @default.
- W4220817852 hasAuthorship W4220817852A5027412987 @default.
- W4220817852 hasAuthorship W4220817852A5049340312 @default.
- W4220817852 hasAuthorship W4220817852A5055983723 @default.
- W4220817852 hasAuthorship W4220817852A5072977591 @default.
- W4220817852 hasBestOaLocation W42208178521 @default.
- W4220817852 hasConcept C126322002 @default.
- W4220817852 hasConcept C164705383 @default.
- W4220817852 hasConcept C201903717 @default.
- W4220817852 hasConcept C207103383 @default.
- W4220817852 hasConcept C2776301958 @default.
- W4220817852 hasConcept C2778248108 @default.
- W4220817852 hasConcept C2778661090 @default.
- W4220817852 hasConcept C2779161974 @default.
- W4220817852 hasConcept C2780638905 @default.
- W4220817852 hasConcept C44249647 @default.
- W4220817852 hasConcept C71924100 @default.
- W4220817852 hasConcept C77350462 @default.
- W4220817852 hasConceptScore W4220817852C126322002 @default.
- W4220817852 hasConceptScore W4220817852C164705383 @default.
- W4220817852 hasConceptScore W4220817852C201903717 @default.
- W4220817852 hasConceptScore W4220817852C207103383 @default.
- W4220817852 hasConceptScore W4220817852C2776301958 @default.
- W4220817852 hasConceptScore W4220817852C2778248108 @default.
- W4220817852 hasConceptScore W4220817852C2778661090 @default.
- W4220817852 hasConceptScore W4220817852C2779161974 @default.
- W4220817852 hasConceptScore W4220817852C2780638905 @default.
- W4220817852 hasConceptScore W4220817852C44249647 @default.
- W4220817852 hasConceptScore W4220817852C71924100 @default.
- W4220817852 hasConceptScore W4220817852C77350462 @default.
- W4220817852 hasLocation W42208178521 @default.
- W4220817852 hasLocation W42208178522 @default.
- W4220817852 hasLocation W42208178523 @default.
- W4220817852 hasOpenAccess W4220817852 @default.
- W4220817852 hasPrimaryLocation W42208178521 @default.
- W4220817852 hasRelatedWork W1156521740 @default.
- W4220817852 hasRelatedWork W1995982834 @default.
- W4220817852 hasRelatedWork W2023570989 @default.
- W4220817852 hasRelatedWork W2071306276 @default.
- W4220817852 hasRelatedWork W2079433673 @default.
- W4220817852 hasRelatedWork W2098571791 @default.
- W4220817852 hasRelatedWork W2144546373 @default.
- W4220817852 hasRelatedWork W2174666533 @default.
- W4220817852 hasRelatedWork W2442149795 @default.
- W4220817852 hasRelatedWork W4310596618 @default.
- W4220817852 hasVolume "40" @default.
- W4220817852 isParatext "false" @default.
- W4220817852 isRetracted "false" @default.
- W4220817852 workType "article" @default.