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- W4220832365 abstract "During surgical treatment skin undergoes extensive deformation, hence it must be able to withstand large mechanical stresses without damage. Therefore, understanding the mechanical properties of skin becomes important. A detailed investigation on the relationship between the three-dimensional deformation response of skin and its microstructure is conducted in the current study. This study also discloses the underlying science of skin viscoelasticity. Deformation response of skin is captured using digital image correlation, whereas micro-CT, scanning electron microscopy and atomic force microscopy are used for microstructure analysis. Skin shows a large lateral contraction and expansion (auxeticity) when stretched parallel and perpendicular to the skin tension lines, respectively. Large lateral contraction is a result of fluid exudation from the tissue, while large rotation of the stiff collagen fibres in the loading direction explains the skin auxeticity. During stress relaxation, lateral contraction and fluid effluxion from skin reveal that tissue volume loss is the intrinsic science of skin viscoelasticity. Furthermore, the results obtained from in vivo study on human skin show the relevance of the ex vivo study to physiological conditions and stretching of the skin during its treatments." @default.
- W4220832365 created "2022-04-03" @default.
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- W4220832365 date "2022-03-01" @default.
- W4220832365 modified "2023-10-06" @default.
- W4220832365 title "Effect of collagen fibre orientation on the Poisson's ratio and stress relaxation of skin: an <i>ex vivo</i> and <i>in vivo</i> study" @default.
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- W4220832365 doi "https://doi.org/10.1098/rsos.211301" @default.
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