FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220841296> ?p ?o ?g. }

• W4220841296 endingPage "98" @default.
• W4220841296 startingPage "89" @default.
• W4220841296 abstract "Accumulating evidence supports the findings of an altered gut microbiota in patients with autoimmune disease. However, existing studies on the role of the gut microbiota in patients with psoriasis have demonstrated conflicting results and have mainly been based on 16s rRNA gene sequencing analysis.To examine whether the gut microbiota of patients with psoriasis was altered in composition and functional potentials compared with healthy controls, and as a second approach compared with healthy cohabitant partners. A further aim was to investigate relationships to disease severity, and seasonal impact on the gut microbiota.In a case-control study, 126 faecal samples were collected from a sample of 53 systemically untreated patients with plaque psoriasis; 52 healthy controls matched for age, sex and body mass index; and 21 cohabitant partners. A subpopulation of 18 patients with psoriasis and 19 healthy controls continued in a longitudinal study, where four to six faecal samples were collected over 9-12 months. The gut microbiota was characterized using shotgun metagenomic sequencing analysis.A significantly lower richness (P = 0·007) and difference in community composition (P = 0·01) of metagenomic species was seen in patients with psoriasis compared with healthy controls, and patients with psoriasis had a lower microbial diversity than their partners (P = 0·04). Additionally, the functional richness was decreased in patients with psoriasis compared with healthy controls (P = 0·01) and partners (P = 0·05). Increased disease severity was correlated with alterations in taxonomy and function, with a slight tendency towards a lower richness of metagenomic species, albeit not significant (P = 0·08). The seasonal analysis showed no shifts in community composition in healthy controls or in patients with psoriasis.The findings of a different gut microbiota in composition and functional potentials between patients with psoriasis and healthy controls support a linkage between the gut microbiota and psoriasis. These findings need to be validated in larger studies, and a potential causal relationship between the gut microbiota and psoriasis still needs to be shown." @default.
• W4220841296 created "2022-04-03" @default.
• W4220841296 creator A5009079207 @default.
• W4220841296 creator A5009118689 @default.
• W4220841296 creator A5021742801 @default.
• W4220841296 creator A5057711245 @default.
• W4220841296 creator A5066665434 @default.
• W4220841296 creator A5077648441 @default.
• W4220841296 date "2022-05-03" @default.
• W4220841296 modified "2023-10-03" @default.
• W4220841296 title "Patients with psoriasis have a dysbiotic taxonomic and functional gut microbiota*" @default.
• W4220841296 cites W1917207513 @default.
• W4220841296 cites W1993399595 @default.
• W4220841296 cites W2008969891 @default.
• W4220841296 cites W2041888440 @default.
• W4220841296 cites W2051166847 @default.
• W4220841296 cites W2053801811 @default.
• W4220841296 cites W2158341557 @default.
• W4220841296 cites W2159381854 @default.
• W4220841296 cites W2171129594 @default.
• W4220841296 cites W2468194934 @default.
• W4220841296 cites W2492950949 @default.
• W4220841296 cites W2563720483 @default.
• W4220841296 cites W2588997555 @default.
• W4220841296 cites W2610471903 @default.
• W4220841296 cites W2623224403 @default.
• W4220841296 cites W2754579667 @default.
• W4220841296 cites W2767249733 @default.
• W4220841296 cites W2787309163 @default.
• W4220841296 cites W2787902098 @default.
• W4220841296 cites W2792605372 @default.
• W4220841296 cites W2890500666 @default.
• W4220841296 cites W2898729889 @default.
• W4220841296 cites W2913282890 @default.
• W4220841296 cites W2916609909 @default.
• W4220841296 cites W2935560613 @default.
• W4220841296 cites W2947211422 @default.
• W4220841296 cites W2978655339 @default.
• W4220841296 cites W2993930062 @default.
• W4220841296 cites W3004540576 @default.
• W4220841296 cites W3022258762 @default.
• W4220841296 cites W3035563103 @default.
• W4220841296 cites W3039592853 @default.
• W4220841296 cites W3045914500 @default.
• W4220841296 cites W3083241614 @default.
• W4220841296 cites W3144590093 @default.
• W4220841296 cites W3168620798 @default.
• W4220841296 cites W4206739528 @default.
• W4220841296 doi "https://doi.org/10.1111/bjd.21245" @default.
• W4220841296 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35289939" @default.
• W4220841296 hasPublicationYear "2022" @default.
• W4220841296 type Work @default.
• W4220841296 citedByCount "11" @default.
• W4220841296 countsByYear W42208412962022 @default.
• W4220841296 countsByYear W42208412962023 @default.
• W4220841296 crossrefType "journal-article" @default.
• W4220841296 hasAuthorship W4220841296A5009079207 @default.
• W4220841296 hasAuthorship W4220841296A5009118689 @default.
• W4220841296 hasAuthorship W4220841296A5021742801 @default.
• W4220841296 hasAuthorship W4220841296A5057711245 @default.
• W4220841296 hasAuthorship W4220841296A5066665434 @default.
• W4220841296 hasAuthorship W4220841296A5077648441 @default.
• W4220841296 hasBestOaLocation W42208412961 @default.
• W4220841296 hasConcept C101985253 @default.
• W4220841296 hasConcept C104317684 @default.
• W4220841296 hasConcept C126322002 @default.
• W4220841296 hasConcept C143121216 @default.
• W4220841296 hasConcept C15151743 @default.
• W4220841296 hasConcept C18903297 @default.
• W4220841296 hasConcept C203014093 @default.
• W4220841296 hasConcept C2777011040 @default.
• W4220841296 hasConcept C2779134260 @default.
• W4220841296 hasConcept C2780564577 @default.
• W4220841296 hasConcept C42407357 @default.
• W4220841296 hasConcept C51679486 @default.
• W4220841296 hasConcept C53565203 @default.
• W4220841296 hasConcept C539455810 @default.
• W4220841296 hasConcept C54355233 @default.
• W4220841296 hasConcept C60644358 @default.
• W4220841296 hasConcept C71924100 @default.
• W4220841296 hasConcept C86803240 @default.
• W4220841296 hasConceptScore W4220841296C101985253 @default.
• W4220841296 hasConceptScore W4220841296C104317684 @default.
• W4220841296 hasConceptScore W4220841296C126322002 @default.
• W4220841296 hasConceptScore W4220841296C143121216 @default.
• W4220841296 hasConceptScore W4220841296C15151743 @default.
• W4220841296 hasConceptScore W4220841296C18903297 @default.
• W4220841296 hasConceptScore W4220841296C203014093 @default.
• W4220841296 hasConceptScore W4220841296C2777011040 @default.
• W4220841296 hasConceptScore W4220841296C2779134260 @default.
• W4220841296 hasConceptScore W4220841296C2780564577 @default.
• W4220841296 hasConceptScore W4220841296C42407357 @default.
• W4220841296 hasConceptScore W4220841296C51679486 @default.
• W4220841296 hasConceptScore W4220841296C53565203 @default.
• W4220841296 hasConceptScore W4220841296C539455810 @default.
• W4220841296 hasConceptScore W4220841296C54355233 @default.
• W4220841296 hasConceptScore W4220841296C60644358 @default.
• W4220841296 hasConceptScore W4220841296C71924100 @default.

• next