FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220855506> ?p ?o ?g. }

• W4220855506 endingPage "359" @default.
• W4220855506 startingPage "351" @default.
• W4220855506 abstract "Background: Aging in people with HIV is associated with increased risk of developing synergistic conditions such as neurocognitive impairment, polypharmacy, and falls. We assessed associations between polypharmacy (use of 5 or more non-ART medications), use of neurocognitive adverse effects (NCAE) medications, and odds of falls in women with HIV (WWH) and without HIV (HIV−). Methods: Self-reported falls and medication use data were contributed semiannually by 1872 (1315 WWH and 557 HIV-) Women's Interagency HIV Study participants between 2014 and 2016. Polypharmacy and NCAE medication use were evaluated separately and jointly in multivariable models to assess their independent contributions to single and multiple falls risk. Results: The proportion of women who reported any fall was similar by HIV status (19%). WWH reported both greater polypharmacy (51% vs. 41%; P < 0.001) and NCAE medication use (44% vs. 37%; P = 0.01) than HIV- women. Polypharmacy conferred elevated odds of single fall [adjusted odds ratio (aOR) 1.67, 95% CI: 1.36 to 2.06; P < 0.001] and multiple falls (aOR 2.31, 95% CI: 1.83 to 2.93; P < 0.001); the results for NCAE medications and falls were similar. Both polypharmacy and number of NCAE medications remained strongly and independently associated with falls in multivariable models adjusted for HIV serostatus, study site, sociodemographics, clinical characteristics, and substance use. Conclusions: Polypharmacy and NCAE medication use were greater among WWH compared with HIV-, and both were independently and incrementally related to falls. Deprescribing and avoidance of medications with NCAEs may be an important consideration for reducing fall risk among WWH and sociodemographically similar women without HIV." @default.
• W4220855506 created "2022-04-03" @default.
• W4220855506 creator A5002438645 @default.
• W4220855506 creator A5007571350 @default.
• W4220855506 creator A5010371161 @default.
• W4220855506 creator A5015714125 @default.
• W4220855506 creator A5018847170 @default.
• W4220855506 creator A5022877697 @default.
• W4220855506 creator A5040237971 @default.
• W4220855506 creator A5044948238 @default.
• W4220855506 creator A5045130073 @default.
• W4220855506 creator A5049374899 @default.
• W4220855506 creator A5050254856 @default.
• W4220855506 creator A5053810340 @default.
• W4220855506 creator A5056403325 @default.
• W4220855506 creator A5057100062 @default.
• W4220855506 creator A5060056613 @default.
• W4220855506 creator A5062716689 @default.
• W4220855506 creator A5064935269 @default.
• W4220855506 creator A5068211949 @default.
• W4220855506 date "2022-07-01" @default.
• W4220855506 modified "2023-09-29" @default.
• W4220855506 title "Polypharmacy Is Associated With Falls in Women With and Without HIV" @default.
• W4220855506 cites W1412982871 @default.
• W4220855506 cites W1958056332 @default.
• W4220855506 cites W1963867953 @default.
• W4220855506 cites W1964444070 @default.
• W4220855506 cites W1965515292 @default.
• W4220855506 cites W1971311909 @default.
• W4220855506 cites W1974281422 @default.
• W4220855506 cites W1981473511 @default.
• W4220855506 cites W1982063891 @default.
• W4220855506 cites W1994481430 @default.
• W4220855506 cites W1998800328 @default.
• W4220855506 cites W2010098948 @default.
• W4220855506 cites W2014171916 @default.
• W4220855506 cites W2019178697 @default.
• W4220855506 cites W2037324843 @default.
• W4220855506 cites W2045598786 @default.
• W4220855506 cites W2055864845 @default.
• W4220855506 cites W2073089263 @default.
• W4220855506 cites W2076579763 @default.
• W4220855506 cites W2092037586 @default.
• W4220855506 cites W2107346787 @default.
• W4220855506 cites W2112778345 @default.
• W4220855506 cites W2126892490 @default.
• W4220855506 cites W2135397849 @default.
• W4220855506 cites W2137321682 @default.
• W4220855506 cites W2141876271 @default.
• W4220855506 cites W2147703536 @default.
• W4220855506 cites W2155478022 @default.
• W4220855506 cites W2158177387 @default.
• W4220855506 cites W2158298030 @default.
• W4220855506 cites W2159571011 @default.
• W4220855506 cites W2161014456 @default.
• W4220855506 cites W2164059021 @default.
• W4220855506 cites W2166487292 @default.
• W4220855506 cites W2171789127 @default.
• W4220855506 cites W2326073726 @default.
• W4220855506 cites W2341496784 @default.
• W4220855506 cites W2472278904 @default.
• W4220855506 cites W2503900576 @default.
• W4220855506 cites W2528509113 @default.
• W4220855506 cites W2542043731 @default.
• W4220855506 cites W2595723182 @default.
• W4220855506 cites W2610359815 @default.
• W4220855506 cites W2623588871 @default.
• W4220855506 cites W2755684038 @default.
• W4220855506 cites W2759881772 @default.
• W4220855506 cites W2766771589 @default.
• W4220855506 cites W2790246287 @default.
• W4220855506 cites W2791013669 @default.
• W4220855506 cites W2792170752 @default.
• W4220855506 cites W2803251184 @default.
• W4220855506 cites W2804279735 @default.
• W4220855506 cites W2891673104 @default.
• W4220855506 cites W2897937392 @default.
• W4220855506 cites W2910688596 @default.
• W4220855506 cites W2913313399 @default.
• W4220855506 cites W2944021445 @default.
• W4220855506 cites W2964133288 @default.
• W4220855506 cites W2995429182 @default.
• W4220855506 cites W3000737134 @default.
• W4220855506 cites W3207530515 @default.
• W4220855506 doi "https://doi.org/10.1097/qai.0000000000002955" @default.
• W4220855506 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35333216" @default.
• W4220855506 hasPublicationYear "2022" @default.
• W4220855506 type Work @default.
• W4220855506 citedByCount "3" @default.
• W4220855506 countsByYear W42208555062023 @default.
• W4220855506 crossrefType "journal-article" @default.
• W4220855506 hasAuthorship W4220855506A5002438645 @default.
• W4220855506 hasAuthorship W4220855506A5007571350 @default.
• W4220855506 hasAuthorship W4220855506A5010371161 @default.
• W4220855506 hasAuthorship W4220855506A5015714125 @default.
• W4220855506 hasAuthorship W4220855506A5018847170 @default.
• W4220855506 hasAuthorship W4220855506A5022877697 @default.
• W4220855506 hasAuthorship W4220855506A5040237971 @default.

• next