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• W4220859348 abstract "Abstract This study focuses on the synthesis and preliminary bio-evaluation of [ 99m Tc]-technetium tricarbonyl procainamide ([ 99m Tc]-technetium tricarbony PA) as a viable cardiac imaging agent. The compound, [ 99m Tc]-technetium tricarbony PA, was synthesized by labelling procainamide with a [ 99m Tc]-technetium tricarbonyl core, yielding a high radiochemical yield and radiochemical purity of 98%. Under optimal circumstances, high radiochemical yield and purity were obtained utilizing [ 99m Tc]-technetium tricarbonyl core within 30 min of incubation at pH 9, 200 µg substrate concentration, and 100 °C reaction temperature. The heart showed a high absorption of 32.39 ± 0.88% of the injected dose/g organ (ID/g), confirming the suitability of [ 99m Tc]-technetium tricarbonyl PA as a viable complex for heart imaging." @default.
• W4220859348 created "2022-04-03" @default.
• W4220859348 creator A5000785486 @default.
• W4220859348 creator A5029444707 @default.
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• W4220859348 creator A5051305337 @default.
• W4220859348 creator A5056942973 @default.
• W4220859348 creator A5073200432 @default.
• W4220859348 date "2022-01-31" @default.
• W4220859348 modified "2023-09-27" @default.
• W4220859348 title "Preparation, biological evaluation and radiolabeling of [^99mTc]-technetium tricarbonyl procainamide as a tracer for heart imaging in mice" @default.
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